Comparison of RP-HPLC columns used for determination of nucleoside metabolic patterns in urine of cancer patients

Bioanalysis

Volumn 4, Issue 10, 2012, Pages 1185-1194

  Waszczuk Jankowska, Małgorzata ^a   Markuszewski, Michał J ^a   Markuszewski, Marcin ^a   Kaliszan, Roman ^a  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLADENOSINE; 3 METHYLCYTOSINE; 5 METHYLURIDINE; 5' METHYLTHIOADENOSINE; 6 N METHYLADENOSINE; 7 METHYLGUANOSINE; ADENOSINE; CYTIDINE; GUANOSINE; INOSINE; N2,N2 DIMETHYLGUANOSINE; N4 ACETYLCYTIDINE; NUCLEOSIDE; PSEUDOURIDINE; UNCLASSIFIED DRUG; XANTHOSINE;

ADULT; AGED; ARTICLE; CANCER PATIENT; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELUTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; RANK SUM TEST; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; STATISTICAL SIGNIFICANCE; URINALYSIS; UROGENITAL TRACT CANCER;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; CREATININE; FEMALE; HUMANS; MALE; METABOLOME; METABOLOMICS; MIDDLE AGED; NUCLEOSIDES; STATISTICS, NONPARAMETRIC; TUMOR MARKERS, BIOLOGICAL; UROGENITAL NEOPLASMS;

EID: 84861895786     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.12.89     Document Type: Article

References (15)

1. Wishart DS, Tzur D, Knox C et al. HMDB: The Human Metabolome Database. Nucl. Acid Res. 35, D521-D526 (2007
2. Shulaev V. Metabolomics technology and bioinformatics. Brief Bioinform. 7(2), 128-39 (2006
3. Lindon JC, Holmes E, Bollard ME, Stanley EG, Nicholson JK. Metabonomics technologies and their applications in physiological monitoring, and drug safety assessment and disease diagnosis. Biomarkers 9(1), 1-31 (2004
4. Van QV, Veenstra TD. How close is the bench to the bedside? Metabolic profiling in cancer research. Gen. Med. 5, 1-6 (2009
5. Nicholson JK, Wilson ID, Lindon JC. Pharmacometabonomics as an effector for personalized medicine. Pharmacogenomics 12(1), 103-111 (2011
6. Lenz EM, Wilson ID. Analytical strategies in metabonomics. J. Proteome Res. 6(2), 443-458 (2007
7. Issaq HJ, Abbott E, Veenstra TD. Utility of separation science in metabolomic studies. J. Sep. Sci. 31, 1936-1947 (2008
8. Dunn WB, Bailey NJC, Johnson HE. Measuring the metabolome: current analytical technologies. Analyst 130(5), 606-625 (2005
9. Lindon JC, Holmes E, Nicholson JK. Metabonomics in pharmaceutical R & D. FEBS J. 274(5), 1140-1151 (2007
10. Theodoridis G, Gika HG, Wilson ID. Mass spectrometry-based holistic analytical approaches for metabolite profiling in systems biology studies. Mass Spectr Rev. 30, 884-906 (2011
11. Markuszewski MJ, Struck W, Waszczuk- Jankowska M, Kaliszan R. Metabolomic approach for determination of urinary nucleosides as potential tumor markers using electromigration techniques. Electrophoresis 31, 2300-2310 (2010
12. Struck W, Waszczuk-Jankowska M, Kaliszan R, Markuszewski MJ. The state-of-the-art determination of urinary nucleosides using chromatographic techniques 'hyphenated' with advanced bioinformatic methods. Anal. Bioanal. Chem. 401, 2039-2050 (2011
13. Szymanska E, Markuszewski MJ, Bodzioch K, Kaliszan R. Development and validation of urinary nucleosides and creatinine assay by capillary electrophoresis with solid phase extraction. J. Pharm. Biomed. Anal. 44, 1118-1126 (2007
14. International Conference on Harmonization of Technical Requirements for the Registration of Pharmaceuticals for Human Use (ICH) Guideline Q2(R1) - Validation of Analytical Procedures: Text and Methodology. ICH Secretariat c/o IFPMA Geneva 1-13 (2005).
15. Szymanska E, Markuszewski MJ, Markuszewski M, Kaliszan R. Altered levels of nucleoside metabolite profiles in urogenital tract cancer measured by capillary electrophoresis. J. Pharm. Biomed. Anal. 53, 1305-1312 (2010