Acute and chronic toxicity of Moringa oleifera Linn leaves extracts

Thai Journal of Veterinary Medicine

Volumn 41, Issue 4, 2011, Pages 417-424

  Chivapat, Songpol ^a   Sincharoenpokai, Pornchai ^a   Saktiyasuthorn, Nalinphat ^a   Shuaprom, Aussavachai ^a   thongsrirak, Pratom ^a   Sakpetch, Apirak ^a   Rungsipipat, Anudep ^b  

^a Medicinal Plant Research Institute   (Thailand)

^b CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Acute; Chronic toxicity; M. Oleifera leaves extract; Mice; Rat

Indexed keywords

ANIMALIA; MORINGA OLEIFERA; MUS; RATTUS; RATTUS NORVEGICUS;

EID: 84861893930     PISSN: 01256491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Charoensin, S. and Wongpoomchai, R. 2010. Mutagenic and antimutagenic activities of aqueous extract of Moringa oleifera leaves. Thai J Toxicol. 25(2): 96-103.
2. Dahot, M.U. 1998. Antimicrobial activity of small protein of Moringa oleifera leaves. J Islamic Aca Sci. 11(1): 27-32.
3. Fahey, J.W. 2005. Moringa oleifera: A review of the medical evidence for its nutritional, therapeutic, and prophylactic properties. Part1. Trees for Life J. 1(5) [Online]. Available: http://www.tfljournal.org/article.php/20051201124931586.
4. Faizi, S., Siddiqui, B.S., Saleem, R., Siddiqui, S., Aftab, K. and Gilani, A.H. 1995. Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. Phytochemistry. 38(4): 957-963.
5. Gad, S.C. 1992. The Rat In: Animal Model in Toxicology. S.C. Gad and C.P. Chengelis (eds). New York: Marcel Dekker: 78-95.
6. Ghasi, S., Nwobodo, E. and Ofili, J.O. 2000. Hypocholesterolemic effects of crude extract of leaf of Moringa oleifera Lam in high-fat diet fed Wistar rats. J Ethnopharmacol. 69: 21-25.
7. Gilani, A.H., Aftab, K., Suria, A., Siddiqui, S., Salem, R., Siddiqui, B.S. and Faizi, S. 1994. Pharmacological studies on hypotensive and spasmolytic activities of pure compounds from Moringa oleifera. Phytotherapy Res. 8: 87-91.
8. Jaiswal, D., Rai, P.K., Kumar, A., Mehta, S. and Watal, G. 2009. Effect of Moringa oleifera Lam. leaves aqueous extract therapy. J Ethnopharmacol. 123: 392-396.
9. Mishra, G., Singh, P., Verma, R., Kumar, S., Srivastav, S., Jha, K.K. and Khosa, R.L. 2011. Traditional uses, phytochemistry and pharmacological properties of Moringa oleifera plant: An overview. Der Phamacia Lettre. 3(2): 141-164.
10. Pal, S.K., Mukherjee, P.K. and Saha, B.P. 1995. Studies on the antiulcer activity of Moringa oleifera Leaf extract on gastric ulcer models in rats. Phytotherapy Res. 9: 463-465.
11. Peckham, J.C. Animal histopathology. In: CRC Handbook of Toxicology. M.J. Derelanko and M.A. Hollinger (eds.) New York: CRC Press: 485-514.
12. Pimainog, Y., Yothinarak, A. and Jornrakate, P. 2003. Reference ranges for hematological and clinical chemistry values in Wistar rats. Bull. Dept. Med. Sci. 45(1): 27-36.
13. Sabale, V., Patel, V., Paranjape, A., Arya, C., Sakarkar, S.N. and Sabale, P.M. 2008. Moringa oleifera (Drumstick): An Overveiw. Phcog Rev. 2(4): 7-13.
14. Wutythamawech, W. 1997. Encyclopedia of Thai Herbs. Bangkok: OS Printing. 365 pp (in Thai).