The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors

Modern Pathology

Volumn 25, Issue 6, 2012, Pages 911-916

  Huth, Cathrin ^a,b   Kloor, Matthias ^a,b   Voigt, Anita Y ^a,b   Bozukova, Gergana ^a,b   Evers, Christina ^a   Gaspar, Harald ^a   Tariverdian, Mirjam ^a   Schirmacher, Peter ^a   Von Knebel Doeberitz, Magnus ^a,b   Bläker, Hendrik ^a,c  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

colorectal cancer; EPCAM TACSTD1; immunohistochemistry; Lynch syndrome; multiplex ligation dependent probe amplification (MLPA)

Indexed keywords

EPITHELIAL CELL ADHESION MOLECULE; PROTEIN MSH2;

ARTICLE; COLORECTAL ADENOMA; DNA EXTRACTION; GENE INACTIVATION; GENE MUTATION; GENE SEQUENCE; GENE SILENCING; GENETIC ANALYSIS; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HETEROZYGOTE; HUMAN; IMMUNOHISTOCHEMISTRY; MOLECULAR GENETICS; MULTIPLEX LIGATION DEPENDENT PROBE AMPLIFICATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TUMOR CELL;

ADENOMA; ADULT; ANTIGENS, NEOPLASM; CARCINOMA; CELL ADHESION MOLECULES; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GERM-LINE MUTATION; GERMANY; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MIDDLE AGED; MULTIPLEX POLYMERASE CHAIN REACTION; MUTS HOMOLOG 2 PROTEIN; PEDIGREE; PHENOTYPE; SEQUENCE DELETION; TUMOR MARKERS, BIOLOGICAL;

EID: 84861884954     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2012.30     Document Type: Article

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