Pilot investigation of a novel testing strategy for bleeding in ventricular assist device recipients

Journal of Heart and Lung Transplantation

Volumn 31, Issue 7, 2012, Pages 750-756

  Joyce, David ^a   Crow, Sheri ^b   Li, Zhuo ^b   Joyce, Lyle ^b   Milano, Carmelo ^c   Rogers, Joseph ^d   Villamizar Ortiz, Nestor ^c   Chen, Dong ^b  

^a UNIV OF MINNESOTA HOSP AND CLINIC   (United States)

^b MAYO CLINIC   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY   (United States)

Author keywords

axial flow; bleeding complications; heart failure; high molecular weight von Willebrand factor multimers; left ventricular assist device

Indexed keywords

BLOOD CLOTTING FACTOR 8; RISTOCETIN; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; AUTOMATED LATEX PARTICLE ENHANCED IMMUNOTURBIDIMETRIC VON WILLEBRAND FACTOR ACTIVITY ASSAY; BLEEDING; BLOOD SAMPLING; BRAIN HEMORRHAGE; CARDIAC PATIENT; CAUTERIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; EPISTAXIS; FOLLOW UP; GASTROINTESTINAL HEMORRHAGE; HEMATOCHEZIA; HUMAN; IMMUNOASSAY; INTERNATIONAL NORMALIZED RATIO; LEFT VENTRICULAR ASSIST DEVICE; MELENA; MULTICENTER STUDY; NOSE; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECIPIENT;

ADULT; AGED; ANTICOAGULANTS; FOLLOW-UP STUDIES; HEART FAILURE; HEART-ASSIST DEVICES; HEMORRHAGE; HUMANS; MICROSPHERES; MIDDLE AGED; NEPHELOMETRY AND TURBIDIMETRY; PILOT PROJECTS; PLATELET AGGREGATION INHIBITORS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS; VON WILLEBRAND FACTOR;

EID: 84861880734     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2012.02.032     Document Type: Article

References (19)

1. Slaughter MS, Rogers JG, Milano CA, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med 2009;361:2241-51.
2. Crow S, John R, Boyle A, et al. Gastrointestinal bleeding rates in recipients of nonpulsatile and pulsatile left ventricular assist devices. J Thorac Cardiovasc Surg 2009;137:208-15.
3. Stern DR, Kazam J, Edwards P, et al. Increased incidence of gastro-intestinal bleeding following implantation of the HeartMate II LVAD. J Card Surg 2010;25:352-6.
4. Geisen U, Heilmann C, Beyersdorf F, et al. Non-surgical bleeding in patients with ventricular assist devices could be explained by acquired von Willebrand disease. Eur J Cardiothorac Surg 2008; 33:679-84.
5. Crow S, Milano C, Joyce L, et al. Comparative analysis of von Willebrand factor profiles in pulsatile and continuous left ventricular assist device recipients. ASAIO J 2010;56:441-5.
6. Uriel N, Pak S-W, Jorde UP, et al. Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation. J Am Coll Cardiol 2010;56:1207-13.
7. Chen D, Daigh CA, Hendricksen JI, et al. A highly-sensitive plasma von Willebrand factor ristocetin cofactor (VWF:RCo) activity assay by flow cytometry. J Thromb Haemost 2008;6:323-30.
8. Popov J, Zhukov O, Ruden S, et al. Performance and clinical utility of a commercial von Willebrand factor collagen binding assay for laboratory diagnosis of von Willebrand disease. Clin Chem 2006;52: 1965-7. (Pubitemid 44470707)
9. Hubbard AR, Hamill M, Beeharry M, Bevan SA, Heath AB. Value assignment of the WHO 2nd International Standard von Willebrand factor, concentrate (09/182). J Thromb Haemost 2011; 9:1638-40.
10. Salem RO, Van Cott EM. A new automated screening assay for the diagnosis of von Willebrand disease. Am J Clin Pathol 2007;127: 730-5.
11. De Vleeschauwer A, Devreese K. Comparison of a new automated von Willebrand factor activity assay with an aggregation von Willebrand ristocetin cofactor activity assay for the diagnosis of von Willebrand disease. Blood Coagul Fibrinolysis 2006;17:353-8. (Pubitemid 43941577)
12. Chen D, Tange JI, Meyers BJ, et al. Validation of an automated latex particle-enhanced immunoturbidimetric von Willebrand factor activity assay. J Thromb Haemost 2011;9:1993-2002.
13. Chand S, McCraw A, Hutton R, Tuddenham EG, Goodall AH. A two-site, monoclonal antibody-based immunoassay for von Willebrand factor- demonstration that vWF function resides in a conformational epitope. Thromb Haemost 1986;55:318-24. (Pubitemid 16074155)
14. Murdock PJ, Woodhams BJ, Matthews KB, Pasi KJ, Goodall AH. von Willebrand factor activity detected in a monoclonal antibody-based ELISA: an alternative to the ristocetin cofactor platelet agglutination assay for diagnostic use. Thromb Haemost 1997;78:1272-7. (Pubitemid 27464598)
15. Goldstein DJ, Zucker M, Arroyo L, et al. Safety and feasibility trial of the MicroMed DeBakey ventricular assist device as a bridge to transplantation. J Am Coll Cardiol 2005;45:962-3. (Pubitemid 40342827)
16. Miller LW, Pagani FD, Russell SD, et al. Use of a continuous-flow device in patients awaiting heart transplantation. N Engl J Med 2007; 357:885-96. (Pubitemid 47347322)
17. Goldstein DJ, Beauford RB. Left ventricular assist devices and bleeding: adding insult to injury. Ann Thorac Surg 2003;75(6 Suppl):S42-47. (Pubitemid 36677189)
18. Cannegieter SC, van der Meer FJ, Briët E, Rosendaal FR. Warfarin and aspirin after heart-valve replacement. N Engl J Med 1994;330: 507-8; author reply 508-9.
19. Crow S, Chen D, Milano C, et al. Acquired von Willebrand syndrome in continuous-flow ventricular assist device recipients. Ann Thorac Surg 2010;90:1263-9; discussion 1269.