Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: A case study on venous thrombosis

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Germain, Marine ^a   Saut, Noémie ^a   Oudot Mellakh, Tiphaine ^a   Letenneur, Luc ^a   Dupuy, Anne Marie ^b   Bertrand, Marion ^a   Alessi, Marie Christine ^a   Lambert, Jean Charles ^c   Zelenika, Diana ^d   Emmerich, Joseph ^a   Tiret, Laurence ^a   Cambien, Francois ^a   Lathrop, Mark ^d   Amouyel, Philippe ^c,e   Morange, Pierre Emmanuel ^a   Trégouët, David Alexandre ^a  

^a INSERM   (France)

^b Montpellier 1 University   (France)

^c UNIV LILLE   (France)

^d CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PROTHROMBIN;

ARTICLE; CASE CONTROL STUDY; CHROMOSOME 11P; CONTROLLED STUDY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE LOCUS; GENE MUTATION; GENETIC ASSOCIATION; GENETIC DISTANCE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; IMPUTATION ANALYSIS; MAJOR CLINICAL STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL ANALYSIS; VEIN THROMBOSIS; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; HUMAN GENOME; MUTATION; RISK FACTOR; STATISTICS;

CASE-CONTROL STUDIES; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GENOME-WIDE ASSOCIATION STUDY; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; STATISTICS AS TOPIC; VENOUS THROMBOSIS;

EID: 84861873825     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038538     Document Type: Article

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