HIV-1 mother-to-child transmission and drug resistance among Brazilian pregnant women with high access to diagnosis and prophylactic measures

Journal of Clinical Virology

Volumn 54, Issue 1, 2012, Pages 15-20

  Alcântara, Keila Correia ^a   Lins, Janaína Bacelar Accioli ^b   Albuquerque, Maly ^b   Aires, Letícia Mara ^b   Cardoso, Ludimila Paula Vaz ^a   Minuzzi, Ana Lúcia ^c   Stefani, Mariane Martins Araújo ^a  

^a FEDERAL UNIVERSITY OF GOIÁS   (Brazil)

^b Anuar Auad Hospital   (Brazil)

^c Institute of Diagnoses and Prevention IDP/APAE   (Brazil)

Author keywords

Drug resistance; HIV 1; Mother to child transmission; Subtype

Indexed keywords

LAMIVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

ADOLESCENT; ADULT; ARTICLE; BIBLIOGRAPHIC DATABASE; BREAST FEEDING; CD4 LYMPHOCYTE COUNT; CLINICAL TRIAL; CONTROLLED STUDY; DELAYED DIAGNOSIS; FEMALE; HEALTH CARE ACCESS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS 2 INFECTION; INFANT; MAJOR CLINICAL STUDY; MALE; MEDICAL SOCIETY; NUCLEOTIDE SEQUENCE; PREGNANT WOMAN; PRENATAL CARE; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEROCONVERSION; SEROLOGY; VAGINAL DELIVERY; VERTICAL TRANSMISSION; VIREMIA; VIRUS DETECTION; VIRUS LOAD; VIRUS MUTATION; VIRUS RESISTANCE; VIRUS TRANSMISSION;

ADOLESCENT; ADULT; BRAZIL; CD4 LYMPHOCYTE COUNT; COHORT STUDIES; DRUG RESISTANCE, VIRAL; FEMALE; GENOTYPE; HIV INFECTIONS; HIV-1; HUMANS; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MALE; MOLECULAR SEQUENCE DATA; POL GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PROSPECTIVE STUDIES; RISK FACTORS; SEQUENCE ANALYSIS, DNA; VIRAL LOAD; YOUNG ADULT;

EID: 84861856485     PISSN: 13866532     EISSN: 18735967     Source Type: Journal    
DOI: 10.1016/j.jcv.2012.01.011     Document Type: Article

References (35)

1. Newell M.L. Current issues in the prevention of mother-to-child transmission of HIV-1 infection. Trans R Soc Trop Med Hyg 2006, 100(1):1-5. [Review].
2. Connor E.M., Sperling R.S., Gelber R., Kiselev P., Scott G., O'Sullivan M.J., et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med 1994, 331:1173-1180.
3. CDC Centers for Disease Control and Prevention. Enhanced perinatal surveillance-participating areas in the United States and dependent areas, 2000-2003. HIV/AIDS Surveillance Suppl Rep 2008, 3:1-35.
4. Henry M., Thuret I., Solas C., Genot S., Colson P., Tamalet C. Vertical transmission of multidrug-resistant Q151M human immunodeficiency virus type 1 strains. Pediatr Infect Dis J 2008, 27(3):278-280.
5. Martinson N.A., Ekouevi D.K., Dabis F., Morris L., Lupodwana P., Tonwe-Gold B., et al. Transmission rates in consecutive pregnancies exposed to single-dose nevirapine in Soweto: South Africa and Abidjan, Cote d'Ivoire. J Acquir Immune Defic Syndr 2007, 45(2):206-209.
6. Veloso V.G., Vasconcelos A.L., Grinsztejn B. Prevenção da transmissão vertical do HIV no Brasil. Bol Epidemiol Aids 1999, 12(3):16-25.
7. Brazil Ministry of Health. National Department of Departament of STD, Aids e Viral Hepatites. Boletim Epidemiológico Aids e DST-Ano VIII, n1° Brasilia; 2011.
8. Whitmore S.K., Patel-Larson A., Espinoza L., Ruffo N.M., Rao S. Missed opportunities to prevent perinatal human immunodeficiency virus transmission in 15 jurisdictions in the United States during 2005-2008. Women Health 2010, 50(5):414-425.
9. Costa Z.B., Machado G.C., Avelino M.M., Gomes F.C., do Filho J.V., Minuzzi A.L., et al. Prevalence and risk factors for Hepatitis C and HIV-1 infections among pregnant women in Central Brazil. Infect Dis 2009, 9:116.
10. Brazil Ministry of Health. National Department of STD, Aids e Viral Hepatitis. Recomendações para profilaxia da transmissão vertical do HIV e terapia antirretroviral em gestantes. Treatment guide; 2010, 46.
11. Cardoso L.P., Queiroz B.B., Stefani M.M. HIV-1 pol phylogenetic diversity and antiretroviral resistance mutations in treatment naïve patients from Central West Brazil. J Clin Virol 2009, 46(2):134-139.
12. Oliveira T., Deforche K., Cassol S., Salminen M., Paraskevis D., Seebregts C., et al. An automated genotyping system for analysis of HIV-1 and other microbial sequences. Bioinfomatics 2005, 21:3797-3800.
13. Gifford R.J., Liu T.F., Rhee S.Y., Kiuchi M., Hue S., Pillay D., et al. The calibrated population resistance tool: standardized genotypic estimation of transmitted HIV-1 drug resistance. Bioinformatics 2009, 20:1-3.
14. Clarke J.R., Braganza R., Mirza A., Stainsby C., Ait-Khaled M., Wright A., et al. Rapid development of genotypic resistance to lamivudine when combined with zidovudine in pregnancy. J Med Virol 1999, 59:364-368.
15. Mandelbrot L., Landreau-Mascaro A., Rekacewicz C., Berrebi A., Beónifla J.L., Agence Nationale de Recherches sur le SIDA (ANRS) 075 Study Group, et al. Lamivudine-zidovudine combination for prevention of maternal-infant transmission of HIV-1. JAMA 2001, 285:2083-2093.
16. Clavel F., Hance A.J. HIV drug resistance. N Engl J Med 2004, 350:1023-1035.
17. Metzner K.J., Giulieri S.G., Knoepfel S.A., Rauch P., Burgisser P., Yerly S. Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients. Clin Infect Dis 2009, 48(2):239-247.
18. Alcântara K.C., Pereira G.A., Albuquerque M., Stefani M.M. Seroreversion in children born to HIV-positive and AIDS mothers from Central West Brazil. Trans R Soc Trop Med Hyg 2009, 103(6):620-626.
19. Amaral E., Assis-Gomes F., Milanez H., Cecatti J.G., Vilela M.M., Silva J.L.P. Implementação oportuna de intervenções para reduzir a transmissão vertical do HIV: uma experiência brasileira bem-sucedida. Rev Panam Salud Publica 2007, 21(6):357-364.
20. Tornatore M., Gonçalves C.V., Mendoza-Sassi R.A., Silveira J.M., D'ávila N.E., Maas C.G., et al. HIV-1 vertical transmission in Rio Grande, Southern Brazil. Int J STD AIDS 2010, 21(5):351-355.
21. Gonçalves V.L., Troiani C., Ribeiro A.A., Spir P.R., Gushiken E.K., Vieira R.B., et al. Vertical transmission of HIV-1 in the western region of the State of São Paulo. Rev Soc Bras Med Trop 2011, 44(1):4-7.
22. Kakehasi F.M., Pinto J.A., Romanelli R.M., Carneiro M., Cardoso C.S., Tavares Mdo C., et al. Determinants and trends in perinatal human immunodeficiency virus type 1 (HIV-1) transmission in the metropolitan area of Belo Horizonte, Brazil: 1998-2005. Mem Inst Oswaldo Cruz 2008, 103(4):351-357.
23. Succi R.C.M., Brazilian Pediatric Society study group to evaluate HIV-1 mother-to-child transmission Mother-to-child transmission of HIV in Brazil during the years 2000 and 2001: results of a multi-centric study. Cad Saúde Pública 2007, 23(3):S379-S389.
24. European Collaborative Study, Boer K., England K., Godfried M.H., Thorne C Mode of delivery in HIV-infected pregnant women and prevention of mother-to-child transmission: changing practices in Western Europe. HIV Med 2010, 11(6):368-378.
25. Warszawski J., Tubiana R., Le Chenadec J., Blanche S., Teglas J.P., Dollfus C., et al. Mother-to-child HIV transmission despite antiretroviral therapy in the ANRS French Perinatal Cohort. AIDS 2008, 22(2):289-299.
26. Townsend C.L., Cortina-Borja M., Peckham C.S., de R.A., Lyall H., Tookey P.A. Low rates of mother-to-child transmission of HIV following effective pregnancy interventions in the United Kingdom and Ireland, 2000-2006. AIDS 2008, 22:973-981.
27. Tubiana R., Le Chenadec J., Rouzioux C., Mandelbrot L., Hamrene K., Dollfus C., et al. Factors associated with mother-to-child transmission of HIV-1 despite a maternal viral load <500 copies/ml at delivery: a case-control study nested in the French perinatal cohort (EPF-ANRS CO1). Clin Infect Dis 2010, 50(4):585-596.
28. D'Ippolito M., Read J.S., Korelitz J., Joao E.C., Mussi-Pinhata M., Rocha N. Missed opportunities for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Latin America and the Caribbean: the NISDI perinatal study. Pediatr Infect Dis J 2007, 26(7):649-653.
29. Turchi M.D., Duarte L.S., Martelli C.M.T. Mother-to-child transmission of HIV: risk factors and missed opportunities for prevention among pregnant women attending health services in Goiânia, Goiás State, Brazil. Cad Saúde Pública 2007, 23(S3):S390-S401.
30. Stefani M.M., Pereira G.A., Lins J.A., Alcantara K.C., Silveira A.A., Viegas A.A., et al. Molecular screening shows extensive HIV-1 genetic diversity in Central West Brazil. J Clin Virol 2007, 39(3):205-209.
31. Cardoso L.P.V., Stefani M.M.A. High level of multidrug resistance mutations in HIV Type 1 pol gene and resistance-associated mutations to enfuvirtide (T-20) among antiretroviral-experienced patients from Central Brazil. Aids Res Hum Retroviruses 2009, 25(10):943-950.
32. Stefani M.M.A., Pereira G.A., Martelli C.M., Shindo N., Galvao-Castro B. Evidence of HIV-1 genetic diversity among pregnant women with AIDS or infected with HIV-1 in Central Brazil. J Acquir Immune Defic Syndr 2000, 23:205-207.
33. Murray M.C., Embree J.E., Ramdahin S.G., Anzala A.O., Njenga S., Plummer F.A. Effect of human immunodeficiency virus (HIV) type 1 viral genotype on mother-to-child transmission of HIV-1. J Infect Dis 2000, 181(2):746-749.
34. Renjifo B., Gilbert P., Chaplin B., Msamanga G., Mwakagile D., Fawzi W., et al. Preferential in-utero transmission of HIV-1 subtype C as compared to HIV-1 subtype A or D. AIDS 2004, 18(12):1629-1636.
35. Renjifo B., Fawzi W., Mwakagile D., Hunter D., Msamanga G., Spiegelman D., et al. Differences in perinatal transmission among human immunodeficiency virus type 1 genotypes. J Hum Virol 2001, 4(1):16-25.