메뉴 건너뛰기




Volumn 27, Issue 6, 2012, Pages 2182-2190

ENOS gene delivery prevents hypertension and reduces renal failure and injury in rats with reduced renal mass

Author keywords

Adenovirus; Endothelin 1; eNOS; Hypertension; Renal failure

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; CREATININE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; NITRATE; NITRIC OXIDE; NITRITE;

EID: 84861838891     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr641     Document Type: Article
Times cited : (21)

References (53)
  • 1
    • 0035723348 scopus 로고    scopus 로고
    • Impaired endothelial function in isolated human uremic resistance arteries
    • Morris ST, McMurray JJ, Spiers A et al. Impaired endothelial function in isolated human uremic resistance arteries. Kidney Int 2001; 60: 1077-1082
    • (2001) Kidney Int , vol.60 , pp. 1077-1082
    • Morris, S.T.1    McMurray, J.J.2    Spiers, A.3
  • 2
    • 0026602536 scopus 로고
    • Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction
    • Lerman A, Sandok EK, Hilderbrand FL et al. Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction. Circulation 1992; 85: 1894-1898
    • (1992) Circulation , vol.85 , pp. 1894-1898
    • Lerman, A.1    Sandok, E.K.2    Hilderbrand, F.L.3
  • 3
    • 0033430948 scopus 로고    scopus 로고
    • Interaction between nitric oxide and endogenous vasoconstrictors in control of renal blood flow
    • Berthod H, Just A, Kirchhein H et al. Interaction between nitric oxide and endogenous vasoconstrictors in control of renal blood flow. Hypertension 1999; 34: 1254-1258
    • (1999) Hypertension , vol.34 , pp. 1254-1258
    • Berthod, H.1    Just, A.2    Kirchhein, H.3
  • 4
    • 0028391520 scopus 로고
    • Dietary supplementation with Larginine ameliorates glomerular hypertension in rats with subtotal nephrectomy
    • Katoh T, Takahashi K, Klahr S et al. Dietary supplementation with Larginine ameliorates glomerular hypertension in rats with subtotal nephrectomy. J Am Soc Nephrol 1994; 4: 1690-1694
    • (1994) J Am Soc Nephrol , vol.4 , pp. 1690-1694
    • Katoh, T.1    Takahashi, K.2    Klahr, S.3
  • 5
    • 0029021148 scopus 로고
    • Hypertension in mice lacking the gene for endothelial nitric oxide synthase
    • Huang PL,Huang Z,MashimoHet al. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995; 377: 239-242
    • (1995) Nature , vol.377 , pp. 239-242
    • Huang, P.L.1    Huang, Z.2    Mashimo, H.3
  • 6
    • 0026782496 scopus 로고
    • Chronic inhibition of nitric oxide synthesis: A new model of arterial hypertension
    • Ribeiro MO, Antunes E, De Nucci G et al. Chronic inhibition of nitric oxide synthesis: a new model of arterial hypertension. Hypertension 1992; 20: 298-303
    • (1992) Hypertension , vol.20 , pp. 298-303
    • Ribeiro, M.O.1    Antunes, E.2    De Nucci, G.3
  • 7
    • 0026667091 scopus 로고
    • Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage
    • Baylis C, Mitruka B, Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest 1992; 90: 278-281
    • (1992) J Clin Invest , vol.90 , pp. 278-281
    • Baylis, C.1    Mitruka, B.2    Deng, A.3
  • 8
    • 62549120730 scopus 로고    scopus 로고
    • Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat
    • Therrien F, Lemieux P, Belanger S et al. Protective effects of angiotensin AT1 receptor blockade in malignant hypertension in the rat. Eur J Pharmacol 2009; 607: 126-134
    • (2009) Eur J Pharmacol , vol.607 , pp. 126-134
    • Therrien, F.1    Lemieux, P.2    Belanger, S.3
  • 9
    • 38349048006 scopus 로고    scopus 로고
    • Nitric oxide deficiency in chronic kidney disease
    • Baylis C. Nitric oxide deficiency in chronic kidney disease. Am J Physiol Renal Physiol 2008; 294: F1-F9
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Baylis, C.1
  • 10
    • 0035079471 scopus 로고    scopus 로고
    • Supplementation with a low dose of L-arginine reduces blood pressure and endothelin-1 production in hypertensive uraemic rats
    • Dumont Y, D'Amours M, Lebel M et al. Supplementation with a low dose of L-arginine reduces blood pressure and endothelin-1 production in hypertensive uraemic rats. Nephrol Dial Transplant 2001; 16: 746-754
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 746-754
    • Dumont, Y.1    D'Amours, M.2    Lebel, M.3
  • 11
    • 0029117554 scopus 로고
    • Agmatine: A novel endogenous vasodilator substance
    • Gao Y, Gumusel B, Koves G et al. Agmatine: a novel endogenous vasodilator substance. Life Sci 1995; 57: 83-86
    • (1995) Life Sci , vol.57 , pp. 83-86
    • Gao, Y.1    Gumusel, B.2    Koves, G.3
  • 12
    • 0037871863 scopus 로고    scopus 로고
    • Effect of tetrahydrobiopterin on blood pressure in rats after subtotal nephrectomy
    • Podjarny E, Benchetrit S, Rathaus M et al. Effect of tetrahydrobiopterin on blood pressure in rats after subtotal nephrectomy. Nephron Physiol 2003; 94: 6-9
    • (2003) Nephron Physiol , vol.94 , pp. 6-9
    • Podjarny, E.1    Benchetrit, S.2    Rathaus, M.3
  • 13
    • 0036154076 scopus 로고    scopus 로고
    • Endothelial dysfunction and hypertension in 5/6 nephrectomized rats are mediated by vascular superoxide
    • Hasdan G, Benchetrit S, Rashid G et al. Endothelial dysfunction and hypertension in 5/6 nephrectomized rats are mediated by vascular superoxide. Kidney Int 2002; 61: 586-590
    • (2002) Kidney Int , vol.61 , pp. 586-590
    • Hasdan, G.1    Benchetrit, S.2    Rashid, G.3
  • 14
    • 0031749824 scopus 로고    scopus 로고
    • Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension
    • Vaziri ND, Oveisi F, Ding Y. Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension. Kidney Int 1998; 53: 1748-1754
    • (1998) Kidney Int , vol.53 , pp. 1748-1754
    • Vaziri, N.D.1    Oveisi, F.2    Ding, Y.3
  • 15
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P, Leone A, Calver A et al. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 1992; 339: 572-575
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3
  • 16
    • 0031968667 scopus 로고    scopus 로고
    • Downregulation of nitric oxide synthase in chronic renal insufficiency: Role of excess PTH
    • Vaziri ND, Ni Z, Wang X et al. Downregulation of nitric oxide synthase in chronic renal insufficiency: role of excess PTH. Am J Physiol 1998; 274: F642-F649
    • (1998) Am J Physiol , vol.274
    • Vaziri, N.D.1    Ni, Z.2    Wang, X.3
  • 17
    • 0033023619 scopus 로고    scopus 로고
    • Dowregulation of neuronal nitric oxide in the rat remnant kidney
    • Roczniak A, Frayer J, Levine D et al. Dowregulation of neuronal nitric oxide in the rat remnant kidney. J Am Soc Nephrol 1999; 10: 704-713
    • (1999) J Am Soc Nephrol , vol.10 , pp. 704-713
    • Roczniak, A.1    Frayer, J.2    Levine, D.3
  • 18
    • 8544221845 scopus 로고    scopus 로고
    • Renal and systemic nitric oxide synthesis in ratswith renalmass reduction
    • Aiello S, Noris M, Todeschini M et al. Renal and systemic nitric oxide synthesis in ratswith renalmass reduction. Kidney Int 1997; 52: 171-181
    • (1997) Kidney Int , vol.52 , pp. 171-181
    • Aiello, S.1    Noris, M.2    Todeschini, M.3
  • 19
    • 0037013179 scopus 로고    scopus 로고
    • Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion
    • ScotlandRS,Morales-RuizM,ChenYet al. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res 2002; 90: 904-910
    • (2002) Circ Res , vol.90 , pp. 904-910
    • Scotland, R.S.1    Morales-Ruiz, M.2    Chen, Y.3
  • 20
    • 0027517744 scopus 로고
    • In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries
    • Lee S, Trapnell B, Rade J et al. In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries. Circ Res 1993; 73: 797-807
    • (1993) Circ Res , vol.73 , pp. 797-807
    • Lee, S.1    Trapnell, B.2    Rade, J.3
  • 21
    • 29244453607 scopus 로고    scopus 로고
    • Neutralization of transforming growth factor-b attenuates hypertension and prevents renal injury in uremic rats
    • Lavoie P, Robitaille G, Agharazii M et al. Neutralization of transforming growth factor-b attenuates hypertension and prevents renal injury in uremic rats. J Hypertens 2005; 23: 1895-1903
    • (2005) J Hypertens , vol.23 , pp. 1895-1903
    • Lavoie, P.1    Robitaille, G.2    Agharazii, M.3
  • 22
    • 1642273893 scopus 로고    scopus 로고
    • Dual constrictor and dilator actions of ET(B) receptors in the rat renal microcirculation: Interactions with ET(A) receptors
    • Just A, Olson AJ, Arendshorst WJ. Dual constrictor and dilator actions of ET(B) receptors in the rat renal microcirculation: interactions with ET(A) receptors. Am J Physiol Renal Physiol 2004; 286: F660-F668
    • (2004) Am J Physiol Renal Physiol , vol.286
    • Just, A.1    Olson, A.J.2    Arendshorst, W.J.3
  • 23
    • 0029095454 scopus 로고
    • Endothelium-specific in vivo gene transfer
    • Schulick AH, Dong G, Newman K et al. Endothelium-specific in vivo gene transfer. Circ Res 1995; 77: 475-485
    • (1995) Circ Res , vol.77 , pp. 475-485
    • Schulick, A.H.1    Dong, G.2    Newman, K.3
  • 24
    • 54049087474 scopus 로고    scopus 로고
    • Endothelial and vascular dysfunction and insulin resistance in rats fed a high-fat, high-sucrose diet
    • Bourgoin F, Bachelard H, Badeau M et al. Endothelial and vascular dysfunction and insulin resistance in rats fed a high-fat, high-sucrose diet. Am J Physiol Heart Circ Physiol 2008; 295: H1044-H1055
    • (2008) Am J Physiol Heart Circ Physiol , vol.295
    • Bourgoin, F.1    Bachelard, H.2    Badeau, M.3
  • 25
    • 77149158486 scopus 로고    scopus 로고
    • Increased ET-1 and reduced ETB receptor expression in uremic hypertensive rats
    • D'Amours M, Chbinou N, Beaudoin J et al. Increased ET-1 and reduced ETB receptor expression in uremic hypertensive rats. Clin Exp Hypertens 2009; 32: 61-69
    • (2009) Clin Exp Hypertens , vol.32 , pp. 61-69
    • D'Amours, M.1    Chbinou, N.2    Beaudoin, J.3
  • 26
    • 0031466011 scopus 로고    scopus 로고
    • Increased immunoreactive endothelin-1 levels in blood vessels and glomeruli of rats with reduced renal mass
    • Larivière R, D'Amours M, Lebel M et al. Increased immunoreactive endothelin-1 levels in blood vessels and glomeruli of rats with reduced renal mass. Kidney Blood Press Res 1997; 20: 372-380
    • (1997) Kidney Blood Press Res , vol.20 , pp. 372-380
    • Larivière, R.1    D'Amours, M.2    Lebel, M.3
  • 27
    • 0344111148 scopus 로고    scopus 로고
    • Effects of losartan and captopril on endothelin-1 production in blood vessels and glomeruli of rats with reduced renal mass
    • Larivière R, Lebel M, Kingma I et al. Effects of losartan and captopril on endothelin-1 production in blood vessels and glomeruli of rats with reduced renal mass. Am J Hypertens 1998; 11: 989-997
    • (1998) Am J Hypertens , vol.11 , pp. 989-997
    • Larivière, R.1    Lebel, M.2    Kingma, I.3
  • 28
    • 0033865622 scopus 로고    scopus 로고
    • Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure
    • Wolf WC, Yoshida H, Agata J et al. Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure. Kidney Int 2000; 58: 730-739
    • (2000) Kidney Int , vol.58 , pp. 730-739
    • Wolf, W.C.1    Yoshida, H.2    Agata, J.3
  • 29
    • 24044503752 scopus 로고    scopus 로고
    • Human eNOS gene delivery attenuates coldinduced elevation of blood pressure in rats
    • Wang X, Cade R, Sun Z. Human eNOS gene delivery attenuates coldinduced elevation of blood pressure in rats. Am J Physiol Heart Circ Physiol 2005; 289: H1161-H1168
    • (2005) Am J Physiol Heart Circ Physiol , vol.289
    • Wang, X.1    Cade, R.2    Sun, Z.3
  • 30
    • 14844309367 scopus 로고    scopus 로고
    • Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction
    • Smith RS Jr, Agata J, Xia CF et al. Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction. Life Sci 2005; 76: 2457-2471
    • (2005) Life Sci , vol.76 , pp. 2457-2471
    • Smith Jr., R.S.1    Agata, J.2    Xia, C.F.3
  • 31
    • 46749102818 scopus 로고    scopus 로고
    • Overexpression of eNOS prevents the development of renovascular hypertension in mice
    • Gava AL, Peotta VA, Cabral AM et al. Overexpression of eNOS prevents the development of renovascular hypertension in mice. Can J Physiol Pharmacol 2008; 86: 458-464
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 458-464
    • Gava, A.L.1    Peotta, V.A.2    Cabral, A.M.3
  • 32
    • 33845348921 scopus 로고    scopus 로고
    • AgharaziiMet al. Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin
    • Lebel M, Rodrigue ME, AgharaziiMet al. Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin. Am J Hypertens 2006; 19: 1286-1292
    • (2006) Am J Hypertens , vol.19 , pp. 1286-1292
    • Lebel, M.1    Rodrigue, M.E.2
  • 33
    • 0027369360 scopus 로고
    • Efficient and selective adenovirus-mediated gene transfer into vascular neointima
    • Guzman R, Lemarchand P, Crystal R et al. Efficient and selective adenovirus-mediated gene transfer into vascular neointima. Circulation 1993; 88: 2838-2848
    • (1993) Circulation , vol.88 , pp. 2838-2848
    • Guzman, R.1    Lemarchand, P.2    Crystal, R.3
  • 34
    • 0345286868 scopus 로고    scopus 로고
    • Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model
    • Alexander MY, Brosnan MJ, Hamilton CA et al. Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model. Cardiovasc Res 1999; 43: 798-807
    • (1999) Cardiovasc Res , vol.43 , pp. 798-807
    • Alexander, M.Y.1    Brosnan, M.J.2    Hamilton, C.A.3
  • 35
    • 0033977864 scopus 로고    scopus 로고
    • Gene transfer of endothelial nitric oxide synthase reduces angiotensin II-induced endothelial dysfunction
    • Nakane H, Miller FJ Jr., Faraci FM et al. Gene transfer of endothelial nitric oxide synthase reduces angiotensin II-induced endothelial dysfunction. Hypertension 2000; 35: 595-601
    • (2000) Hypertension , vol.35 , pp. 595-601
    • Nakane, H.1    Miller Jr., F.J.2    Faraci, F.M.3
  • 36
    • 0032879970 scopus 로고    scopus 로고
    • Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice
    • Lake-Bruse KD, Faraci FM, Shesely EG et al. Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice. Am J Physiol 1999; 277: H770-H7706
    • (1999) Am J Physiol , vol.277
    • Lake-Bruse, K.D.1    Faraci, F.M.2    Shesely, E.G.3
  • 37
    • 0032796241 scopus 로고    scopus 로고
    • Endothelin ETA receptor blockade prevents the progression of renal failure and hypertension in uremic rats
    • Brochu E, Lacasse MS, Moreau C et al. Endothelin ETA receptor blockade prevents the progression of renal failure and hypertension in uremic rats. Nephrol Dial Transplant 1999; 14: 1881-1888
    • (1999) Nephrol Dial Transplant , vol.14 , pp. 1881-1888
    • Brochu, E.1    Lacasse, M.S.2    Moreau, C.3
  • 38
    • 0034910285 scopus 로고    scopus 로고
    • Blood pressure-independent effects of angiotensin AT1 receptor blockade on renal endothelin-1 production in hypertensive uremic rats
    • Dumont Y, D'Amours M, Lebel M et al. Blood pressure-independent effects of angiotensin AT1 receptor blockade on renal endothelin-1 production in hypertensive uremic rats. J Hypertens 2001; 19: 1479-1487
    • (2001) J Hypertens , vol.19 , pp. 1479-1487
    • Dumont, Y.1    D'Amours, M.2    Lebel, M.3
  • 39
    • 3142540898 scopus 로고    scopus 로고
    • Nitric oxide, angiotensin II, and hypertension
    • Zhou MS, Schulman IH, Raij L. Nitric oxide, angiotensin II, and hypertension. Semin Nephrol 2004; 24: 366-378
    • (2004) Semin Nephrol , vol.24 , pp. 366-378
    • Zhou, M.S.1    Schulman, I.H.2    Raij, L.3
  • 40
    • 0004559340 scopus 로고
    • Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endotheliumderived relaxing factor
    • De Nucci G, Thomas R, D'Orléans-Juste P et al. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endotheliumderived relaxing factor. Proc Natl Acad Sci USA 1988; 85: 9797-9800
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9797-9800
    • De Nucci, G.1    Thomas, R.2    D'Orléans-Juste, P.3
  • 41
    • 0030710211 scopus 로고    scopus 로고
    • Role of increased glomerular protein traffic in the progression of renal failure
    • Bruzzi I, Benigni A, Remuzzi G. Role of increased glomerular protein traffic in the progression of renal failure. Kidney Int 1997; 62: S29-S31
    • (1997) Kidney Int , vol.62
    • Bruzzi, I.1    Benigni, A.2    Remuzzi, G.3
  • 42
    • 0027091616 scopus 로고
    • Control of renal hemodynamics during intrarenal and systemic blockade of nitric oxide synthesis in conscious dogs
    • Granger JP, Alberola AM, Salazar FJ et al. Control of renal hemodynamics during intrarenal and systemic blockade of nitric oxide synthesis in conscious dogs. J Cardiovasc Pharmacol 1992; 20: S160-S162
    • (1992) J Cardiovasc Pharmacol , vol.20
    • Granger, J.P.1    Alberola, A.M.2    Salazar, F.J.3
  • 43
    • 0026322262 scopus 로고
    • Effects of NG-nitro-L-arginine methyl ester on renal function and blood pressure
    • Lahera V, Salon MG, Miranda-Guardiola F et al. Effects of NG-nitro-L-arginine methyl ester on renal function and blood pressure. Am J Physiol 1991; 261: F1033-F1037
    • (1991) Am J Physiol , vol.261
    • Lahera, V.1    Salon, M.G.2    Miranda-Guardiola, F.3
  • 45
    • 0027462550 scopus 로고
    • Locally produced EDRF control preglomerular resistance and ultrafiltration coefficient
    • Deng A, Baylis C. Locally produced EDRF control preglomerular resistance and ultrafiltration coefficient. Am J Physiol 1993; 264: F212-F215
    • (1993) Am J Physiol , vol.264
    • Deng, A.1    Baylis, C.2
  • 46
    • 0025897548 scopus 로고
    • Modulation of angiotensin II-induced vasoconstriction by endothelium-derived relaxing factor in the isolated microperfused rabbit afferent arteriole
    • Ito S, Johnson CS, Carretero OA. Modulation of angiotensin II-induced vasoconstriction by endothelium-derived relaxing factor in the isolated microperfused rabbit afferent arteriole. J Clin Invest 1991; 87: 1656-1663
    • (1991) J Clin Invest , vol.87 , pp. 1656-1663
    • Ito, S.1    Johnson, C.S.2    Carretero, O.A.3
  • 47
    • 0026007186 scopus 로고
    • Endothelium-derived relaxing factor modulates endothelin action in afferent arterioles
    • Ito S, Juncos LA, Nushiro N et al. Endothelium-derived relaxing factor modulates endothelin action in afferent arterioles. Hypertension 1991; 17: 1052-1056
    • (1991) Hypertension , vol.17 , pp. 1052-1056
    • Ito, S.1    Juncos, L.A.2    Nushiro, N.3
  • 48
    • 0026602775 scopus 로고
    • Role of nitric oxide in renal papillary blood flow and sodium excretion
    • Mattson DL, Roman RJ, Cowley AWJ. Role of nitric oxide in renal papillary blood flow and sodium excretion. Hypertension 1992; 19: 766-769
    • (1992) Hypertension , vol.19 , pp. 766-769
    • Mattson, D.L.1    Roman, R.J.2    Cowley, A.W.J.3
  • 49
    • 0025100874 scopus 로고
    • Release of endothelin from the porcine aorta: Inhibition by endothelium-derived nitric oxide
    • Boulanger C, Lüscher TF. Release of endothelin from the porcine aorta: inhibition by endothelium-derived nitric oxide. J Clin Invest 1990; 85: 587-590
    • (1990) J Clin Invest , vol.85 , pp. 587-590
    • Boulanger, C.1    Lüscher, T.F.2
  • 50
    • 0028914674 scopus 로고
    • L-arginine supplementation antagonizes the effects of angiotensin II and endothelin 1 on mesangial cell proliferation
    • Mattana J, Singhal PC. L-arginine supplementation antagonizes the effects of angiotensin II and endothelin 1 on mesangial cell proliferation. Cell Physiol Biochem 1995; 5: 176-192
    • (1995) Cell Physiol Biochem , vol.5 , pp. 176-192
    • Mattana, J.1    Singhal, P.C.2
  • 51
    • 0028966014 scopus 로고
    • Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells
    • Trachtman H, Futterweit S, Singhal P. Nitric oxide modulates the synthesis of extracellular matrix proteins in cultured rat mesangial cells. Biochem Biophys Res Commun 1995; 207: 120-125
    • (1995) Biochem Biophys Res Commun , vol.207 , pp. 120-125
    • Trachtman, H.1    Futterweit, S.2    Singhal, P.3
  • 52
    • 0034979237 scopus 로고    scopus 로고
    • Tetrahydrobiopterin: A critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction?
    • Tiefenbacher CP. Tetrahydrobiopterin: a critical cofactor for eNOS and a strategy in the treatment of endothelial dysfunction? Am J Physiol Heart Circ Physiol 2001; 280: H2484-H2488
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Tiefenbacher, C.P.1
  • 53
    • 0034677947 scopus 로고    scopus 로고
    • NAD(P)H oxidase: Role in cardiovascular biology and disease
    • Griendling K, Sorescu D, Ushio-Fukai M. NAD(P)H oxidase: role in cardiovascular biology and disease. Circ Res 2000; 86: 494-501
    • (2000) Circ Res , vol.86 , pp. 494-501
    • Griendling, K.1    Sorescu, D.2    Ushio-Fukai, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.