Inwardly rectifying potassium channel Kir4.1 is localized at the calyx endings of vestibular afferents

Neuroscience

Volumn 215, Issue , 2012, Pages 209-216

  Udagawa, T ^a   Tatsumi, N ^a   Tachibana, T ^a   Negishi, Y ^a   Saijo, H ^a   Kobayashi, T ^a   Yaguchi, Y ^a   Kojima, H ^a   Moriyama, H ^a   Okabe, M ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Calyx ending; Inner ear; Inwardly rectifying potassium channel; Kir4.1; Sensation of balance; Synapse

Indexed keywords

INWARDLY RECTIFYING POTASSIUM CHANNEL; KIR4.1 PROTEIN; MESSENGER RNA; POTASSIUM ION; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MATURATION; CHANNEL GATING; EMBRYO; GENE; GENE EXPRESSION; GENE LOCATION; GLIA CELL; HAIR CELL; KIR4.1 GENE; MOUSE; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SATELLITE CELL; VESTIBULAR NERVE;

ANIMALS; ANIMALS, NEWBORN; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INTERMEDIATE FILAMENT PROTEINS; KCNQ POTASSIUM CHANNELS; MICE; MICE, INBRED C57BL; MICROSCOPY, IMMUNOELECTRON; NERVE TISSUE PROTEINS; NEUROGLIA; NEURONS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RNA, MESSENGER; SATELLITE CELLS, PERINEURONAL; TUBULIN; VESTIBULE, LABYRINTH;

EID: 84861826253     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.04.037     Document Type: Article

References (23)

1. Bockenhauer D., Feather S., Stanescu H.C., Bandulik S., Zdebik A.A., Reichold M., Tobin J., Lieberer E., Sterner C., Landoure G., Arora R., Sirimanna T., Thompson D., Cross J.H., van't Hoff W., Al Masri O., Tullus K., Yeung S., Anikster Y., Klootwijk E., Hubank M., Dillon M.J., Heitzmann D., Arcos-Burgos M., Knepper M.A., Dobbie A., Gahl W.A., Warth R., Sheridan E., Kleta R. Epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations. N Engl J Med 2009, 360:1960-1970.
2. Breuskin I., Bodson M., Thelen N., Thiry M., Borgs L., Nguyen L., Stolt C., Wegner M., Lefebvre P.P., Malgrange B. Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10. J Neurochem 2010, 114:1827-1839.
3. Eatock R.A., Rusch A., Lysakowski A., Saeki M. Hair cells in mammalian utricles. Otolaryngol Head Neck Surg 1998, 119:172-181.
4. Eatock R.A., Xue J., Kalluri R. Ion channels in mammalian vestibular afferents may set regularity of firing. J Exp Biol 2008, 211:1764-1774.
5. Goldberg J.M. Theoretical analysis of intercellular communication between the vestibular type I hair cell and its calyx ending. J Neurophysiol 1996, 76:1942-1957.
6. + circulation in the mammalian inner ear. Physiology (Bethesda) 2006, 21:336-345.
7. Hibino H., Horio Y., Inanobe A., Doi K., Ito M., Yamada M., Gotow T., Uchiyama Y., Kawamura M., Kubo T., Kurachi Y. An ATP-dependent inwardly rectifying potassium channel , KAB-2 (Kir4. 1) in cochlear stria vascularis of inner ear its specific subcellular localization and correlation with the formation of endocochlear potential. J Neurosci 1997, 17:4711-4721.
8. Hibino H., Horio Y., Fujita A., Inanobe A., Doi K., Gotow T., Uchiyama Y., Kubo T., Kurachi Y. Expression of an inwardly rectifying K(+) channel, Kir4.1, in satellite cells of rat cochlear ganglia. Am J Physiol 1999, 277:C638-C644.
9. Hibino H., Inanobe A., Furutani K., Murakami S., Findlay I., Kurachi Y. Inwardly rectifying potassium channels: their structure, function, and physiological roles. Physiol Rev 2010, 90:291-366.
10. Higashi K., Fujita A., Inanobe A., Tanemoto M., Doi K., Kubo T., Kurachi Y. An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain. Am J Physiol Cell Physiol 2001, 281:C922-C931.
11. Holt J.C., Chatlani S., Lysakowski A., Goldberg J.M. Quantal and nonquantal transmission in calyx-bearing fibers of the turtle posterior crista. J Neurophysiol 2007, 98:1083-1101.
12. + currents in type I hair cells and calyx afferent endings of the developing rat utricle. J Neurosci 2006, 26:10253-10269.
13. + channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses. Am J Physiol Cell Physiol 2002, 282:C1396-C1403.
14. Ishii M., Horio Y., Tada Y., Hibino H., Inanobe A., Ito M., Yamada M., Gotow T., Uchiyama Y., Kurachi Y. Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Muller cell membrane: their regulation by insulin and laminin signals. J Neurosci 1997, 17:7725-7735.
15. + channel mutated in a form of dominant deafness, is expressed in the inner ear and the central auditory pathway. Proc Natl Acad Sci U S A 2000, 97:4333-4338.
16. Lim R., Kindig A.E., Donne S.W., Callister R.J., Brichta A.M. Potassium accumulation between type I hair cells and calyx terminals in mouse crista. Exp Brain Res 2011, 210:607-621.
17. Lysakowski A., Gaboyard-Niay S., Calin-Jageman I., Chatlani S., Price S.D., Eatock R.A. Molecular microdomains in a sensory terminal, the vestibular calyx ending. J Neurosci 2011, 31:10101-10114.
18. Neusch C., Rozengurt N., Jacobs R.E., Lester H.A., Kofuji P. Kir4.1 potassium channel subunit is crucial for oligodendrocyte development and in vivo myelination. J Neurosci 2001, 21:5429-5438.
19. Riddle R.D., Johnson R.L., Laufer E., Tabin C. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 1993, 75:1401-1416.
20. Rozengurt N., Lopez I., Chiu C.-S., Kofuji P., Lester H.A., Neusch C. Time course of inner ear degeneration and deafness in mice lacking the Kir4.1 potassium channel subunit. Hear Res 2003, 177:71-80.
21. Shen W., Tian X., Day M., Ulrich S., Tkatch T., Nathanson N.M., Surmeier D.J. Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons. Nat Neurosci 2007, 10:1458-1466.
22. Soto E., Vega R., Budelli R. The receptor potential in type I and type II vestibular system hair cells: a model analysis. Hear Res 2002, 165:35-47.
23. Sousa A.D., Andrade L.R., Salles F.T., Pillai A.M., Buttermore E.D., Bhat M.A., Kachar B. The septate junction protein caspr is required for structural support and retention of KCNQ4 at calyceal synapses of vestibular hair cells. J Neurosci 2009, 29:3103-3108.