Novel treatment for congenital FXIII deficiency

Blood

Volumn 119, Issue 22, 2012, Pages 5060-5061

  Kohler, Hans P ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8 ANTIBODY; BLOOD CLOTTING FACTOR 8 CONCENTRATE; BLOOD CLOTTING FACTOR 8A; BLOOD CLOTTING FACTOR 8B; RECOMBINANT BLOOD CLOTTING FACTOR 8; UNCLASSIFIED DRUG;

ANTIBODY TITER; AUTOSOMAL RECESSIVE DISORDER; BLEEDING TENDENCY; BLOOD CLOTTING TEST; BLOOD TRANSFUSION; CLINICAL FEATURE; DIAGNOSTIC ACCURACY; DRUG EFFICACY; DRUG SAFETY; HEMOPHILIA A; HUMAN; NOTE; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ASSEMBLY; PROTHROMBIN TIME; THROMBIN TIME; TREATMENT OUTCOME;

EID: 84861824336     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-04-422493     Document Type: Note

References (10)

1. Inbal A, Oldenburg J, Carcao M, Rosholm A, Tehranchi R, Nugent D. Recombinant factor XIII: a safe and novel treatment for congenital factor XIII deficiency. Blood. 2012; 119(22):5111-5117.
2. Duckert F, June E, Shmerling DH. A hitherto undescribed congenital hemorrhagic diathesis probably due to fibrin stabilizing factor deficiency. Thromb Diath Haemorrh. 1960;5:179-186.
3. Laki K, Lorand L. On the solubility of fibrin clots. Science. 1948;108(2802):280.
4. Schroeder V, Meili E, Cung T, Schmutz P, Kohler HP. Characterisation of six novel A-subunit mutations leading to congenital factor XIII deficiency and molecular analysis of the first diagnosed patient with this rare bleeding disorder. Thromb Haemost. 2006;95(1):77-84.
5. Kohler HP, Ichinose A, Seitz R et al. Diagnosis and classification of factor XIII deficiencies. J Thromb Haemost. 2011;9(7):1404-1406.
6. Hsieh L, Nugent D. Factor XIII deficiency. Haemophilia. 2008;14(6):1190-1200.
7. MuszbekL, Bereczky Z, Bagoly Z, Komaromi I, Katona E. Factor XIII: a coagulation factor with multiple plasmatic and cellular functions. Physiol Rev. 2011;91(3):931-972.
8. 2 administration in patients with congenital factor XIII deficiency. Blood. 2006;108(1):57-62.
9. Hayat M, Ariens RA, Moayyedi P, Grant PJ, O'Mahony S. Coagulation factor XIII and markers of thrombin generation and fibrinolysis in patients with inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2002;14(3):249-256. (Pubitemid 34259273)
10. Pihusch R, Salat C, Göhring P, et al. Factor XIII activity levels in patients with allogeneic haematopoietic stem cell transplantation and acute graft-versus-host disease of the gut. Br J Haematol. 2002;117(2):469-476. (Pubitemid 34451166)