New allele-specific real-time PCR system for warfarin dose genotyping equipped with an automatic interpretative function that allows rapid, accurate, and user-friendly reporting in clinical laboratories

Thrombosis Research

Volumn 130, Issue 1, 2012, Pages 104-109

  Kim, Sollip ^a   Lee, Hye Won ^b   Lee, Woochang ^b   Um, Tae Hyun ^a   Cho, Chong Rae ^a   Chun, Sail ^b   Min, Won Ki ^b  

^a Inje University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Automatic interpretation; Dosing; Genotyping; Real time PCR; Warfarin

Indexed keywords

WARFARIN;

ACCURACY; ALGORITHM; ALLELE; ANTICOAGULANT THERAPY; ARTICLE; CLINICAL LABORATORY; CLINICAL PRACTICE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; GENE AMPLIFICATION; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MOLECULAR PROBE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROCESS DEVELOPMENT; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; TIME; VALIDATION STUDY;

ALGORITHMS; ALLELES; ANTICOAGULANTS; ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; DRUG DOSAGE CALCULATIONS; GENOTYPE; HUMANS; MIXED FUNCTION OXYGENASES; POLYMORPHISM, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SOFTWARE; TIME FACTORS; WARFARIN;

EID: 84861812036     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2011.08.021     Document Type: Article

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