Analysis of glutathione peroxidase 1 gene polymorphism and Keshan disease in Heilongjiang Province, China

Genetics and Molecular Research

Volumn 10, Issue 4, 2011, Pages 2996-3001

  Wei, H L ^a   Pei, J R ^a   Jiang, C X ^a   Zhou, L W ^a   Lan, T ^a   Liu, M ^a   Wang, T ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Gene polymorphism; Glutathione peroxidase 1; Keshan disease; Selenium

Indexed keywords

GLUTATHIONE PEROXIDASE 1; SELENIUM; GLUTATHIONE PEROXIDASE;

ARTICLE; CHINESE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EXON; GENE MUTATION; GENETIC POLYMORPHISM; GLUTATHIONE PEROXIDASE 1 GENE; HUMAN; KESHAN DISEASE; MUTATION RATE; PROMOTER REGION; SELENIUM BLOOD LEVEL; BLOOD; CARDIOMYOPATHY; CASE CONTROL STUDY; CHINA; ENTEROVIRUS INFECTION; ENZYMOLOGY; FEMALE; GENETIC ASSOCIATION; GENETICS; GENOTYPE; HEART MUSCLE CELL; MALE; METABOLISM; PATHOLOGY;

CARDIOMYOPATHIES; CASE-CONTROL STUDIES; CHINA; ENTEROVIRUS INFECTIONS; EXONS; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; GLUTATHIONE PEROXIDASE; HUMANS; MALE; MUTATION RATE; MYOCYTES, CARDIAC; POLYMORPHISM, GENETIC; PROMOTER REGIONS, GENETIC; SELENIUM;

EID: 84861801720     PISSN: None     EISSN: 16765680     Source Type: Journal    
DOI: 10.4238/2011.December.2.1     Document Type: Article

References (15)

1. Chen X (1986). Selenium and cardiomyopathy (Keshan disease). Acta Pharmacol. Toxicol. 59 (Suppl 7): 325-330.
2. Group KDPaT (1976). Selenium and water-soil causality of Keshan Disease. J. Hygiene Res. 3: 259-263.
3. Hamanishi T, Furuta H, Kato H, Doi A, et al. (2004). Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients. Diabetes 53: 2455-2460.
4. He HFL and Yuan Q (2001). Cloning and sequence analysis of human glutathione peroxidase 1. Chin. Pharm. J. 36: 343-345.
5. Hu YJ and Diamond AM (2003). Role of glutathione peroxidase 1 in breast cancer: loss of heterozygosity and allelic differences in the response to selenium. Cancer Res. 63: 3347-3351.
6. Kote-Jarai Z, Durocher F, Edwards SM, Hamoudi R, et al. (2002). Association between the GCG polymorphism of the selenium dependent GPX1 gene and the risk of young onset prostate cancer. Prostate Cancer Prostatic Dis. 5: 189-192.
7. Lei C, Niu X, Wei J, Zhu J, et al. (2009). Interaction of glutathione peroxidase-1 and selenium in endemic dilated cardiomyopathy. Clin. Chim. Acta 399: 102-108.
8. Lei XG, Cheng WH and McClung JP (2007). Metabolic regulation and function of glutathione peroxidase-1. Annu. Rev. Nutr. 27: 41-61.
9. Matsuzawa D, Hashimoto K, Shimizu E, Fujisaki M, et al. (2005). Functional polymorphism of the glutathione peroxidase 1 gene is associated with personality traits in healthy subjects. Neuropsychobiology 52: 68-70.
10. Rotruck JT, Pope AL and Garther H (1973). Selenium: biochemical role as a component of glutathione peroxidase. Science 179: 588-590.
11. Venardos KM, Perkins A, Headrick J and Kaye DM (2007). Myocardial ischemia-reperfusion injury, antioxidant enzyme systems, and selenium: a review. Curr. Med. Chem. 14: 1539-1549.
12. WHO (1973). Trace elements in human nutrition. Report of a WHO expert committee. World Health Organ Tech. Rep. Ser. 532: 1-65.
13. Yang J, Wang T, Wu C and Liu C (2010). Selenium level surveillance for the year 2007 of Keshan disease in endemic areas and analysis on surveillance results between 2003 and 2007. Biol. Trace Elem. Res. 138: 53-59.
14. Yu W (1999). Review of Chinese research on Keshan Disease. Chin. J. Epidemiol. 20: 11-14.
15. Zhu LZ, Xia YM and Yang GQ (1982). Blood glutathione peroxidase activities of populations in Keshan Disease affected and non-affected areas. Acta Nutr. Sin. 4: 229-233.