Strain-specific neutralizing antibody responses against human cytomegalovirus envelope glycoprotein N

Clinical and Vaccine Immunology

Volumn 19, Issue 6, 2012, Pages 909-913

  Pati, Sunil K ^a   Novak, Zdenek ^a   Purser, Misty ^a   Arora, Nitin ^a   Mach, Michael ^c   Britt, William J ^a,b,d   Boppana, Suresh B ^a,b  

^a University of Alabama at Birmingham   (United States)

^b University of Alabama at Birmingham   (United States)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOMEGALOVIRUS ANTIBODY; ENVELOPE GLYCOPROTEIN H; ENVELOPE GLYCOPROTEIN N; GLYCOPROTEIN B; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VIRUS ANTIGEN; VIRUS ENVELOPE PROTEIN;

ADULT; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; FEMALE; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; REINFECTION; VIRUS NEUTRALIZATION; VIRUS RECOMBINANT; VIRUS STRAIN;

ADOLESCENT; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CYTOMEGALOVIRUS; FEMALE; GENOTYPE; HUMANS; RECOMBINATION, GENETIC; VIRAL ENVELOPE PROTEINS; YOUNG ADULT;

EID: 84861752979     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00092-12     Document Type: Article

References (29)

1. Abe Y, et al. 2004. Effect of the addition of oligosaccharides on the biological activities and antigenicity of influenza A/H3N2 virus hemagglutinin. J. Virol. 78:9605-9611. (Pubitemid 39187078)
2. Boppana SB, Rivera LB, Fowler KB, Mach M, Britt WJ. 2001. Intrauterine transmission of cytomegalovirus to infants of women with preconceptional immunity. N. Engl. J. Med. 344:1366 -1371.
3. Boppana SB, Smith RJ, Stagno S, Britt WJ. 1992. Evaluation of a microtiter plate fluorescent-antibody assay for rapid detection of human cytomegalovirus infection. J. Clin. Microbiol. 30:721-723.
4. Britt WJ, Vugler L, Butfiloski EJ, Stephens EB. 1990. Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing antibody response. J. Virol. 64:1079 -1085.
5. Burkhardt C, Himmelein S, Britt W, Winkler T, Mach M. 2009. Glycoprotein N subtypes of human cytomegalovirus induce a strain-specific antibody response during natural infection. J. Gen. Virol. 90: 1951-1961.
6. Chou SW. 1990. Differentiation of cytomegalovirus strains by restriction analysis of DNA sequences amplified from clinical specimens. J. Infect. Dis. 162:738 -742.
7. Coaquette A, et al. 2004. Mixed cytomegalovirus glycoprotein B genotypes in immunocompromised patients. Clin. Infect. Dis. 39:155-161. (Pubitemid 38971482)
8. Fries BC, Chou S, Boeckh M, Torok-Storb B. 1994. Frequency distribution of cytomegalovirus envelope glycoprotein genotypes in bone marrow transplant recipients. J. Infect. Dis. 169:769 -774.
9. Grundy JE, et al. 1988. Symptomatic cytomegalovirus infection in sero-positive kidney recipients: reinfection with donor virus rather than reactivation of recipient virus. Lancet ii:132-135.
10. Ishibashi K, et al. 2007. Association of the outcome of renal transplantation with antibody response to cytomegalovirus strain-specific glycoprotein H epitopes. Clin. Infect. Dis. 45:60-67. (Pubitemid 46984617)
11. Klein M, Schoppel K, Amvrossiadis N, Mach M. 1999. Strain-specific neutralization of human cytomegalovirus isolates by human sera. J. Virol. 73:878-886. (Pubitemid 29036738)
12. Leach CT, et al. 1994. A longitudinal study of cytomegalovirus infection in human immunodeficiency virus type 1-seropositive homosexual men: molecular epidemiology and association with disease progression. J. Infect. Dis. 170:293-298. (Pubitemid 24226354)
13. Meyer H, Sundqvist VA, Pereira L, Mach M. 1992. Glycoprotein gp116 of human cytomegalovirus contains epitopes for strain-common and strain-specific antibodies. J. Gen. Virol. 73:2375-2383.
14. Murphy E, et al. 2003. Coding potential of laboratory and clinical strains of human cytomegalovirus. Proc. Natl. Acad. Sci. U. S. A. 100:14976-14981. (Pubitemid 37518002)
15. Novak Z, et al. 2008. Cytomegalovirus strain diversity in seropositive women. J. Clin. Microbiol. 46:882- 886.
16. Novak Z, et al. 2009. Enzyme-linked immunosorbent assay method for detection of cytomegalovirus strain-specific antibody responses. Clin. Vaccine Immunol. 16:288 -290.
17. Pati SK, et al. 2011. Abstr. 36th Annu. Int. Herpesvirus Workshop, Gdansk, Poland, 24 to 28 July 2011, abstr 5.20.
18. Pignatelli S, et al. 2003. Human cytomegalovirus glycoprotein N (gpUL73-gN) genomic variants: identification of a novel subgroup, geographical distribution and evidence of positive selective pressure. J. Gen. Virol. 84:647- 655.
19. Puchhammer-Stockl E, et al. 2006. Emergence of multiple cytomegalovirus strains in blood and lung of lung transplant recipients. Transplantation 81:187-194.
20. Rasmussen L, Geissler A, Cowan C, Chase A, Winters M. 2002. The genes encoding the gCIII complex of human cytomegalovirus exist in highly diverse combinations in clinical isolates. J. Virol. 76:10841-10848. (Pubitemid 35176201)
21. Renzette N, Bhattacharjee B, Jensen JD, Gibson L, Kowalik TF. 2011. Extensive genome-wide variability of human cytomegalovirus in congenitally infected infants. PLoS Pathog. 7:e1001344. doi:10.1371/journal.ppat.1001344.
22. Ross SA, et al. 2010. Cytomegalovirus reinfections in healthy seroimmune women. J. Infect. Dis. 201:386 -389.
23. Ross SA, et al. 2011. Mixed infection and strain diversity in congenital cytomegalovirus infection. J. Infect. Dis. 204:1003-1007.
24. Shimamura M, Mach M, Britt WJ. 2006. Human cytomegalovirus infection elicits a glycoprotein M (gM)/gN-specific virus-neutralizing anti-body response. J. Virol. 80:4591- 4600.
25. Urban M, Britt W, Mach M. 1992. The dominant linear neutralizing antibody-binding site of glycoprotein gp86 of human cytomegalovirus is strain specific. J. Virol. 66:1303-1311.
26. Urban M, Klein M, Britt WJ, Hassfurther E, Mach M. 1996. Glycoprotein H of human cytomegalovirus is a major antigen for the neutralizing humoral immune response. J. Gen. Virol. 77:1537-1547. (Pubitemid 26248669)
27. Wei X, et al. 2003. Antibody neutralization and escape by HIV-1. Nature 422:307-312. (Pubitemid 36378357)
28. Yamamoto AY, et al. 2010. Human cytomegalovirus reinfection is associated with intrauterine transmission in a highly cytomegalovirus-immune maternal population. Am. J. Obstet. Gynecol. 202:297.e1-297.e8.
29. Zinkernagel RM, Hengartner H. 2006. Protective 'immunity' by pre-existent neutralizing antibody titers and preactivated T cells but not by so-called 'immunological memory.' Immunol. Rev. 211:310-319. (Pubitemid 43882982)