Real-time PCR-based analysis of BRAF V600E mutation in low and intermediate grade lymphomas confirms frequent occurrence in hairy cell leukaemia

Hematological Oncology

Volumn 30, Issue 4, 2012, Pages 190-193

  Ewalt, Mark ^a   Nandula, Subhadra ^a   Phillips, Adrienne ^a   Alobeid, Bachir ^a   Murty, Vundavalli V ^a   Mansukhani, Mahesh M ^a   Bhagat, Govind ^a  

^a NewYork Presbyterian Hospital   (United States)

Author keywords

BRAF V600E; Hairy cell leukaemia; Non Hodgkin lymphoma

Indexed keywords

B RAF KINASE; CLADRIBINE; PENTOSTATIN; RITUXIMAB;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER SIZE; CLINICAL ARTICLE; FEMALE; GENE MUTATION; HAIRY CELL LEUKEMIA; HUMAN; LARGE CELL LYMPHOMA; MALE; MICROSATELLITE INSTABILITY; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION;

ADULT; AGED; FEMALE; HUMANS; LEUKEMIA, HAIRY CELL; LYMPHOMA, B-CELL; LYMPHOMA, NON-HODGKIN; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; POINT MUTATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS B-RAF; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; YOUNG ADULT;

EID: 84861739190     PISSN: 02780232     EISSN: 10991069     Source Type: Journal    
DOI: 10.1002/hon.1023     Document Type: Article

References (13)

1. Tiacci E, Trifonov V, Schiavoni G, et al. BRAF mutations in hairy-cell leukemia. N Engl J Med 2011; 364(24): 2305-2315.
2. Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417(6892): 949-954.
3. Lee JW, Yoo NJ, Soung YH, et al. BRAF mutations in non-Hodgkin's lymphoma. Br J Cancer 2003; 89(10): 1958-1960.
4. Chapman MA, Lawrence MS, Keats JJ, et al. Initial genome sequencing and analysis of multiple myeloma. Nature 2011; 471(7339): 467-472.
5. Boyd EM, Bench AJ, van 't Veer MB, et al. High resolution melting analysis for detection of BRAF exon 15 mutations in hairy cell leukaemia and other lymphoid malignancies. Br J Haematol 2011; 155(5): 609-612.
6. Foucar K, Falini B, Catovsky D, Stein H. Hairy cell leukaemia. In WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, (4th ed). Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, et al (eds.). International Agency for Research on Cancer: Lyon, France, 2008; 188-190.
7. Amorim MR, Vargas FR, Llerena JC Jr, Pombo-de-Oliveira MS. DNA extraction from fixed cytogenetic cell suspensions. Genet Mol Res 2007; 6(3): 500-503.
8. Benlloch S, Paya A, Alenda C, et al. Detection of BRAF V600E mutation in colorectal cancer: comparison of automatic sequencing and real-time chemistry methodology. J Mol Diagn 2006; 8(5): 540-543.
9. Domingo E, Espin E, Armengol M, et al. Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation. Genes Chromosomes Cancer 2004; 39(2): 138-142.
10. Borie C, Colas C, Dartigues P, et al. The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms. Int J Cancer 2009; 125(10): 2360-2366.
11. Cawley J. The biology of hairy cell leukemia. Leuk Lymphoma 2009; 50(Suppl 1): 8-11.
12. Cawley JC, Hawkins SF. The biology of hairy-cell leukaemia. Curr Opin Hematol 2010; 17(4): 341-349.
13. Tiacci E, Liso A, Piris M, Falini B. Evolving concepts in the pathogenesis of hairy-cell leukaemia. Nat Rev Cancer 2006; 6(6): 437-448.