Sequence-specific recognition of a PxLPxI/L motif by an ankyrin repeat tumbler lock

Science Signaling

Volumn 5, Issue 226, 2012, Pages

  Xu, Chao ^a   Jin, Jing ^b   Bian, Chuanbing ^a   Lam, Robert ^a,g   Tian, Ruijun ^b   Weist, Ryan ^c,d   You, Linya ^c,d   Nie, Jianyun ^c,e   Bochkarev, Alexey ^a   Tempel, Wolfram ^a   Tan, Chris S ^b   Wasney, Gregory A ^a   Vedadi, Masoud ^a   Gish, Gerald D ^b   Arrowsmith, Cheryl H ^a,f   Pawson, Tony ^b,f   Yang, Xiang Jiao ^c,d   Min, Jinrong ^a,f  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^e KUNMING MEDICAL UNIVERSITY   (China)

^f UNIVERSITY OF TORONTO   (Canada)

^g PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANKYRIN; ANKYRIN REPEAT FAMILY A PROTEIN 2; BINDING PROTEIN; HISTONE DEACETYLASE 4; HISTONE DEACETYLASE 5; HISTONE DEACETYLASE 9; MEGALIN; MEMBRANE RECEPTOR; PROTEIN 14 3 3; PROTEOME; REGULATORY FACTOR X ASSOCIATED ANKYRIN CONTAINING PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; ANKRA2 PROTEIN, HUMAN; DNA BINDING PROTEIN; HDAC4 PROTEIN, HUMAN; HDAC5 PROTEIN, HUMAN; HDAC9 PROTEIN, HUMAN; HISTONE DEACETYLASE; REPRESSOR PROTEIN; RFX5 PROTEIN, HUMAN;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ESCHERICHIA COLI; EUKARYOTE; ISOTHERMAL TITRATION CALORIMETRY; MASS SPECTROMETRY; NONHUMAN; PEPTIDE ANALYSIS; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; STRUCTURE ANALYSIS; CELL STRAIN HEK293; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY; PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

14-3-3 PROTEINS; ANKYRIN REPEAT; ANKYRINS; DNA-BINDING PROTEINS; HEK293 CELLS; HISTONE DEACETYLASES; HUMANS; MUTATION; PROTEIN BINDING; REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84861730836     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2002979     Document Type: Article

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