Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: Correlation between the CALUX bioassay and GC-HRMS

Chemosphere

Volumn 88, Issue 7, 2012, Pages 881-887

  Croes, K ^a,d   Vandermarken, T ^a   Van Langenhove, K ^a   Elskens, M ^a   Desmedt, M ^b   Roekens, E ^b   Denison, M S ^c   Van Larebeke, N ^d   Baeyens, W ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b Vlaamse Milieumaatschappij   (Belgium)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Atmospheric depositions; CALUX; Correlation; Dioxin like PCBs; GC HRMS; PCDD Fs

Indexed keywords

ATMOSPHERIC CHEMISTRY; CORRELATION METHODS; DEPOSITION; GENE EXPRESSION; METEOROLOGICAL PROBLEMS; POLYCHLORINATED BIPHENYLS;

ATMOSPHERIC DEPOSITIONS; CALUX; DIOXIN-LIKE PCBS; GC-HRMS; PCDD/FS;

ORGANIC POLLUTANTS;

DIOXIN LIKE POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL; POLYCHLORINATED DIBENZODIOXIN; POLYCHLORINATED DIBENZOFURAN; UNCLASSIFIED DRUG;

ATMOSPHERIC DEPOSITION; BIOASSAY; CORRELATION; FRACTIONATION; MEASUREMENT METHOD; PCB; PCDD;

ARTICLE; ATMOSPHERIC DEPOSITION; BELGIUM; BIOASSAY; CHEMICALLY ACTIVATED LUCIFERASE GENE EXPRESSION BIOASSAY; FLEMISH MEASUREMENT NETWORK; MASS FRAGMENTOGRAPHY; MAXIMUM ALLOWABLE CONCENTRATION; MEASUREMENT; RESIDENTIAL AREA; RURAL AREA;

BELGIUM; FLANDERS;

EID: 84861714770     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2012.03.097     Document Type: Article

References (24)

1. Baeyens W., Leermakers M., Elskens M., Van Larebeke N., De Bont R., Vanderperren H., Fontaine A., Degroodt J.-M., Goeyens L., Hanot V., Windal I. PCBs and PCDD/FS in fish and fish products and their impact on the human body burden in Belgium. Arch. Environ. Contam. Toxicol. 2007, 52:563-571.
2. Croes K., Van Langenhove K., Den Hond E., Bruckers L., Colles A., Koppen G., Loots I., Nelen V., Schoeters G., Nawrot T., Van Larebeke N., Denison M.S., Vandermarken T., Elskens M., Baeyens W. Quantification of PCDD/Fs and dioxin-like PCBs in small amounts of human serum using the sensitive H1L7.5c1 mouse hepatoma cell line: optimization and analysis of human serum samples from adolescents of the Flemish human biomonitoring program FLEHS II. Talanta 2011, 85:2484-2491.
3. Croes K., Van Langenhove K., Elskens M., Desmedt M., Roekens E., Kotz A., Denison M.S., Baeyens W. Analysis of PCDD/Fs and dioxin-like PCBs in atmospheric deposition samples from the Flemish measurement network: optimization and validation of a new CALUX bioassay method. Chemosphere 2011, 82:718-724.
4. Denison M.S., He G., Baston D.S., Tsutsumi T. Third generation CALUX luciferase reporter vectors - amplification of dioxin responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Organohalogen Compd. 2008, 70:772-775.
5. Desmedt M., Roekens E. New policy in Flanders to link environmental levels of PCDD/F and dioxin-like PCBS to health. Organohalogen Compd. 2011, 73:2042-2045.
6. Elskens M., Baston D.S., Stumpf C., Haedrich J., Keupers I., Croes K., Denison M.S., Baeyens W., Goeyens L. CALUX measurements: statistical inferences for the dose response curve. Talanta 2011, 85:1966-1973.
7. He G., Tsutsumi T., Zhao B., Baston B.S., Zhao J., Heath-Pagliuso S., Denison M.S. Third generation ah receptor-responsive luciferase reporter plasmids: amplification of dioxin responsive elements dramatically increases CALUX bioassay sensitivity and responsiveness. Toxicol. Sci. 2011, 10.1093/toxsci/kfr189.
8. Kakimoto H., Oka H., Yumiko H., Ushijima S., Toriba A., Kizu R., Hayakawa K. Comparison of compositions of polychlorinated dibenzo-p-dioxines (PCDDs) and dibenzofurans (PCDFs) in air and soil samples collected in Ishikawa. J. Health Sci. 2004, 50(1):58-65.
9. Man R., Pingan P., Sukun Z., Liping Y., Bixian M., Guoying S., Jiamo F. Determination of dioxins in atmospheric deposition by HRGC/HRMS. Chin. J. Anal. Chem. 2006, 34(1):16-20.
10. Moon H.-B., Lee S.-J., Choi H.-G., Ok G. Atmospheric deposition of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in urban and suburban areas of Korea. Chemosphere 2005, 58:1525-1534.
11. Nakamura T., Nakai K., Matsumura T., Suzuki S., Saito Y., Satoh H. Determination of dioxins and polychlorinated biphenyls in breast milk, maternal blood and cord blood from residents of Tohoku, Japan. Sci. Total Environ. 2008, 394:39-51.
12. Nizzetto L., Cassani C., Di Guardo A. Deposition of PCBs in mountains: the forest filter effect of different forest ecosystem types. Ecotoxicol. Environ. Saf. 2006, 63:75-83.
13. Oka H., Kakimoto H., Miyata Y., Yonezawa Y., Niikawa A., Kyudoh H., Kizu R. Atmospheric deposition of polychorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in Kanazawam, Japan. J. Health Sci. 2006, 52(3):300-307.
14. Sanctorum H., Windal I., Hanot V., Goeyens L., Baeyens W. Arch. Environ. Contam. Toxicol. 2007, 52:317-325.
15. Tsutsumi T., Amakura T., Nakamura M., Brown D.J., Clark G.C., Sasaki K., Toyoda M., Maitani T. Validation of the CALUX bioassay for the screening of PCDD/Fs and dioxin-like PCBs in retail fish. Analyst 2003, 128:486-492.
16. Van den Berg M., Birnbaum L., Bosveld A., Brunström B., Cook P., Feeley M., Giesy J.P., Hanberg A., Hasegawa R., Kennedy S.W. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ. Health Perspect. 1998, 106:775.
17. Van Langenhove K., Croes K., Denison M.S., Baeyens W., Elskens M. The CALUX bio-assay: analytical comparison between mouse hepatoma cell lines with a low (H1L6.1c3) and high (H1L7.5c1) number of dioxin response elements. Talanta 2011, 85:2039-2046.
18. Van Overmeire I., Carbonnelle S., Schoeters G., Van Cleuvenbergen R., Windal I., Van Wouwe N., Goeyens L. Control of bovine milk samples by CALUX bioassay and GC-HRMS analysis. Organohalogen Compd. 2003, 60:243-246.
19. Van Wouwe N., Windal I., Vanderperren H., Eppe G., Xhrouet C., Massart A.-C., Debacker N., Sasse A., Baeyens W., De Pauw E., Sartor F., Van Oyen H., Goeyens L. Validation of the CALUX bioassay for PCDD/F analyses in human blood plasma and comparison with GC-HRMS. Talanta 2004, 63:1157-1167.
20. Vandermarken T., Van Langenhove K., Elskens M., Desmedt M., Roekens E., Denison M., Baeyens W., Croes K. Implementation of the CALUX bioassay for the analysis of PCDD/F's and dioxin-like PCB's in atmospheric deposition samples from the Flemish Monitoring Network. Organohalogen Compd. 2011, 73:1924-1927.
21. VDI 2090/1 guidelines. (22.09.11). http://www.vdi.de/401.0.html.
22. Vmm reports PCDD/Fs and PCB 126 in deposition samples (Dutch). (22.09.11). http://www.vmm.be/lucht/meetresultaten/dioxines-en-pcbs-resultaten.
23. Wevers M., De Fré R., Desmedt M. Effect of backyard burning on dioxin deposition and air concentrations. Chemosphere 2004, 54:1351-1356.
24. Wittsiepe J., Fürst P., Schrey P., Lemm F., Kraft M., Eberwein G., Winneke G., Wilhelm G. PCDD/F and dioxin-like PCB in human blood and milk from German mothers. Chemosphere 2007, 67:S286-S294.