A cytotoxic triterpenoid saponin from under-ground parts of Gypsophila pilulifera Boiss.& Heldr.

Fitoterapia

Volumn 83, Issue 4, 2012, Pages 699-703

  Arslan, Idris ^a   Celik, Ali ^a   Chol, Jang Hak ^b  

^a PAMUKKALE UNIVERSITY   (Turkey)

^b Institute of Clinical Chemistry   (North Korea)

Author keywords

A549; Cytotoxicity; Gypsophila pilulifera; HPLC; NMR; Saponin

Indexed keywords

3 O BETA DEXTRO GALACTOPYRANOSYL(1-2)[BETA DEXTRO XYLOPYRANOSYL(1-3)] BETA DEXTRO GLUCOPYRANOSYL QUILLAIC ACID 28 O BETA DEXTRO GLUCOPYRANOSYL(1-3)[BETA DEXTRO XYLOPYRANOSYL(1-4)] ALPHA LEVO RHAMNOPYRANOSYL(1-2) BETA DEXTRO FUCOPYRANOSYL ESTER; CYTOTOXIC AGENT; SAPONIN DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CARYOPHYLLACEAE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; GYPSOPHILA PILULIFERA; IC 50; PLANT ROOT; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

CARYOPHYLLACEAE; GYPSOPHILA;

EID: 84861708529     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.02.005     Document Type: Article

References (13)

1. K. Hostettmann, and A. Marston Saponins J.D. Phillipon, D.C. Ayres, H. Baxter, Chemistry and pharmacology of natural products 1995 Cambridge University Press Cambridge
2. A. Weng, K. Jenett-Siems, P. Schmieder, D. Bachran, C. Bachran, and C. Görick A convenient method for saponin isolation in tumour therapy J Chromatogr B 878 2010 713 718
3. M. Rochd, F. Fons, A. Chahlaoui, and M. Henry How to characterize three caryophyllaceous species by the mean of the ration of two glucuronide prosaponins? Acta Bot Gall 151 2004 285 292
4. J.R. Wang, H. Zhou, Z.H. Jiang, and L. Liu Two new triterpene saponins from the anti-inflammatory saponin fraction of Ilex pubescens root Chem Biodivers 5 2008 1369 1376
5. M. Rajasekaran, A.G. Nair, W.J. Hellstrom, and S.C. Sikka Spermicidal activity of an antifungal saponin obtained from the tropical herb Mollugo pentaphylla Contraception 47 1993 401 412
6. G.S. Sidhu, and D.G. Oakenfull A mechanism for the hypocholesterolaemic activity of saponins Br J Nutr 55 1986 643 649
7. M. Amoros, B. Fauconnier, and R.L. Girre In vitro antiviral activity of a saponin from Anagallis arvensis, Primulaceae, against herpes simplex virus and poliovirus Antiviral Res 8 1987 13 25
8. Marciani DJ. Triterpene saponin analogs having adjuvant and immunostimulatory activity. US Patent 1999, 5, 977,081; 11 Fevr.
9. X. Zhu, G. Wu, J. Xiang, H. Luo, S. Luo, and H. Zhu New pregnane saponins from Ecdysanthera rosea and their cytotoxicity Fitoterapia 82 2011 632 636
10. A. Ivanova, B. Mikhova, T. Batsalova, B. Dzhambazov, and I. Kostova New furostanol saponins from Smilax aspera L. and their in vitro cytotoxicity Fitoterapia 82 2011 282 287
11. N. De Tommasi, S. Piacente, F. De Simone, and C. Pizza Characterization of three new triterpenoid saponins from Ardisia japonica J Nat Prod 56 1993 1669 1675
12. Z. Jia, K. Koike, and T. Nikaido Major Triterpenoid Saponins from Saponaria officinalis J Nat Prod 61 1998 1368 1373
13. D.A. Scudiero, R.H. Shoemaker, K.D. Paull, A. Monks, S. Tierney, and T.H. Nofziger Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines Cancer Res 48 1988 4827 4833