Integrin alphavbeta6 is involved in measles protein-induced airway immune suppression

Cytokine

Volumn 59, Issue 1, 2012, Pages 59-64

  Wu, Xing Mao ^a   Liao, Yu Wei ^a   Wang, Hai Yuan ^a   Ji, Kai Qiang ^a   Li, Guo Fu ^a   Zang, Bin ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Dendritic cell; Immune suppression; Lung; Measles; Regulatory T cell

Indexed keywords

ALPHAVBETA6 INTEGRIN; GAMMA INTERFERON; INTERLEUKIN 4; MEASLES VIRUS C PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AIRWAY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DENDRITIC CELL; FLOW CYTOMETRY; IMMUNE DEFICIENCY; IMMUNOCOMPETENT CELL; LUNG ALVEOLUS EPITHELIUM; LUNG PARENCHYMA; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTIGENS, NEOPLASM; DENDRITIC CELLS; EPITHELIAL CELLS; IMMUNE TOLERANCE; INTEGRINS; LUNG; MALE; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES, REGULATORY; VIRAL PROTEINS;

EID: 84861703951     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.04.005     Document Type: Article

References (19)

1. Goh A.Y., Sekaran D., Roziah M. Corticosteroid rescue in late paediatric acute respiratory distress syndrome. Respirology 1999, 4:295-297.
2. Griffin D.E. Measles virus-induced suppression of immune responses. Immunol Rev 2010, 236:176-189.
3. Billiau A., Matthys P. Interferon-[gamma]: a historical perspective. Cytokine Growth Factor Rev 2009, 20:97-113.
4. Yu X.L., Cheng Y.M., Shi B.S., Qian F.X., Wang F.B., Liu X.N., et al. Measles virus infection in adults induces production of IL-10 and is associated with increased CD4+ CD25+ regulatory T cells. J Immunol 2008, 181:7356-7366.
5. Sakaguchi S., Miyara M., Costantino C.M., Hafler D.A. FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol 2010, 10:490-500.
6. Bettini M., Vignali D.A. Regulatory T cells and inhibitory cytokines in autoimmunity. Curr Opin Immunol 2009, 21:612-618.
7. Moutasim K.A., Jenei V., Sapienza K., Marsh D., Weinreb P.H., Violette S.M., et al. Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis. J Pathol 2011, 223:366-377.
8. Tabata T., Kawakatsu H., Maidji E., Sakai T., Sakai K., Fang-Hoover J., et al. Induction of an epithelial integrin [alpha]v[beta]6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-[beta]1 and increased collagen production. Am J Pathol 2008, 172:1127-1140.
9. Reutter G.L., Cortese-Grogan C., Wilson J., Moyer S.A. Mutations in the measles virus C protein that up regulate viral RNA synthesis. Virology 2001, 285:100-109.
10. Aluwihare P., Munger J.S. What the lung has taught us about latent TGF-{beta} activation. Am J Respir Cell Mol Biol 2008, 39:499-a.
11. Coombes J.L., Siddiqui K.R.R., Arancibia-Cárcamo C.V., Hall J., Sun C.M., Belkaid Y., et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGFbeta and retinoic acid-dependent mechanism. J Exp Med 2007, 204:1757-1764.
12. Guilliams M., Crozat K., Henri S., Tamoutounour S., Grenot P., Devilard E., et al. Skin-draining lymph nodes contain dermis-derived CD103-dendritic cells that constitutively produce retinoic acid and induce Foxp3+ regulatory T cells. Blood 2010, 115:1958-1968.
13. Chen X., Song C.H., Feng B.S., Li T.L., Li P., Zheng P.Y., et al. Intestinal epithelial cell-derived integrin alphavbeta6 plays an important role in the induction of regulatory T cells and inhibits an antigen-specific Th2 response. J Leukoc Biol 2011.
14. Vinante F., Krampera M., Morosato L., Rigo A., Romagnani S., Pizzolo G. Peripheral T lymphocyte cytokine profile (IFNgamma, IL-2, IL-4) and CD30 expression/release during measles infection. Haematologica 1999, 84:683-689.
15. Flavell R.A., Sanjabi S., Wrzesinski S.H., Licona-Limón P. The polarization of immune cells in the tumour environment by TGFbeta. Nat Rev Immunol 2010, 10:554-567.
16. Huang H., Dawicki W., Zhang X., Town J., Gordon J.R. Tolerogenic dendritic cells induce CD4+CD25hiFoxp3+ regulatory T cell differentiation from CD4+CD25-Foxp3+ effector T Cells. J Immunol 2010, 185:5003-5010.
17. Hanabuchi S., Ito T., Park W.R., Watanabe N., Shaw J.L., Roman E., et al. Thymic stromal lymphopoietin-activated plasmacytoid dendritic cells induce the generation of FOXP3+ regulatory T cells in human thymus. J Immunol 2010, 184:2999-3007.
18. Kwon H.K., Lee C.G., So J.S., Chae C.S., Hwang J.S., Sahoo A., et al. Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders. Proc Natl Acad Sci USA 2010, 107:2159-2164.
19. Sakaguchi S., Ono M., Setoguchi R., Yagi H., Hori S., Fehervari Z., et al. Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006, 212:8-27.