ARD1 binding to RIP1 mediates doxorubicin-induced NF-κB activation

Biochemical and Biophysical Research Communications

Volumn 422, Issue 2, 2012, Pages 291-297

  Park, Jonggyu ^a   Kanayama, Atsuhiro ^a   Yamamoto, Kazuo ^a   Miyamoto, Yusei ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Acetylation; ARD1; Doxorubicin; HA; HEK; MEF; Myc; NF B; NLS; RIP1; TNF

Indexed keywords

ACYLTRANSFERASE; ACYLTRANSFERASE INHIBITOR; DOXORUBICIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RECEPTOR INTERACTING PROTEIN 1; RECEPTOR PROTEIN; SMALL INTERFERING RNA; TRICHOSTATIN A; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CELL STRESS; DNA DAMAGE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MUTANT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN;

ACETYLTRANSFERASES; CELL NUCLEUS; DNA DAMAGE; DOXORUBICIN; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; NF-KAPPA B; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN STRUCTURE, TERTIARY; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS; STRESS, PHYSIOLOGICAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84861694221     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.04.150     Document Type: Article

References (20)

1. Karl S., Pritschow Y., Volcic M., Häcker S., Baumann B., Wiesmüller L., Debatin K.M., Fulda S. Identification of a novel pro-apopotic function of NF-kappa B in the DNA damage response. J. Cell Mol. Med. 2009, 10:4239-4256.
2. Hayden M.S., Ghosh S. Shared principles in NF-kappaB signaling. Cell 2008, 132:344-362.
3. Kelliher M.A., Grimm S., Ishida Y., Kuo F., Stanger B.Z., Leder P. The death domain kinase RIP mediates the TNF-induced NF-kappaB signal. Immunity 1998, 3:297-303.
4. Hur G.M., Lewis J., Yang Q., Lin Y., Nakano H., Nedospasov S., Liu Z.G. The death domain kinase RIP has an essential role in DNA damage-induced NF-kappa B activation. Genes Dev. 2003, 17:873-882.
5. Kanayama A., Seth R.B., Sun L., Ea C.K., Hong M., Shaito A., Chiu Y.H., Deng L., Chen Z.J. TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains. Mol. Cell 2004, 15:535-548.
6. Ea C.K., Deng L., Xia Z.P., Pineda G., Chen Z.J. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol. Cell 2006, 22:245-257.
7. Janssens S., Tinel A., Lippens S., Tschopp J. PIDD mediates NF-kappaB activation in response to DNA damage. Cell 2005, 123:1079-1092.
8. Huang T.T., Wuerzberger-Davis S.M., Wu Z.H., Miyamoto S. Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress. Cell 2003, 115:565-576.
9. Mabb A.M., Wuerzberger-Davis S.M., Miyamoto S. PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress. Nat. Cell Biol. 2006, 9:986-993.
10. Jin H.-S., Lee D.-H., Kim D.-H., Chung J.-H., Lee S.-J., Lee T.H. cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-κB activation. Cancer Res. 2009, 69:1782-1791.
11. Whiteway M., Szostak J.W. The ARD1 gene of yeast functions in the switch between the mitotic cell cycle and alternative developmental pathways. Cell 1985, 43:483-492.
12. Caron C., Boyault C., Khochbin S. Regulatory cross-talk between lysine acetylation and ubiquitination: role in the control of protein stability. Bioessays 2005, 4:408-415.
13. Jeong J.W., Bae M.K., Ahn M.Y., Kim S.H., Sohn T.K., Bae M.H., Yoo M.A., Song E.J., Lee K.J., Kim K.W. Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation. Cell 2002, 111:709-720.
14. Kuo H.P., Lee D.F., Chen C.T., Liu M., Chou C.K., Lee H.J., Du Y., Xie X., Wei Y., Xia W., Weihua Z., Weihua J.Y., Yang Y.J., Yen C.J., Huang T.H., Tan M., Xing G., Zhao Y., Lin C.H., Tsai S.F., Fidler I.J., Hung M.C. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Sci. Signal. 2010, 3:ra9.
15. Arnesen T., Anderson D., Baldersheim C., Lanotte M., Varhaug J.E., Lillehaug J.R. Identification and characterization of the human ARD1-NATH protein acetyltransferase complex. Biochem. J. 2005, 386:433-443.
16. Yi C.H., Sogah D.K., Boyce M., Degterev A., Christofferson D.E., Yuan J. A genome-wide RNAi screen reveals multiple regulators of caspase activation. J. Cell Biol. 2007, 179:619-626.
17. Tergaonkar V., Bottero V., Ikawa M., Li Q., Verma I.M. IkappaB kinase-independent IkappaBalpha degradation pathway: functional NF-kappaB activity and implications for cancer therapy. Mol. Cell Biol. 2003, 23:8070-8083.
18. Meylan E., Tschopp J. The RIP kinases: crucial integrators of cellular stress. Trends Biochem. Sci. 2005, 30:151-159.
19. Hsu H., Huang J., Shu H.B., Baichwal V., Goeddel D.V. TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 1996, 4:387-396.
20. Biton S., Ashkenazi A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNFα feedforward signaling. Cell 2011, 145:92-103.