Fifty years of Weibel-Palade bodies: The discovery and early history of an enigmatic organelle of endothelial cells

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 6, 2012, Pages 979-984

  Weibel, E R ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Endothelial cells; Von Willebrand factor; Weibel Palade bodies

Indexed keywords

VON WILLEBRAND FACTOR;

ARTERY ENDOTHELIUM; BLOOD CLOTTING; CELL FUNCTION; CELL MEMBRANE; CELL SHAPE; CELLULAR DISTRIBUTION; CYTOPLASM; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; HUMAN; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PULMONARY ARTERY; RESEARCH; REVIEW; UMBILICAL VEIN; WEIBEL PALADE BODY;

ANIMALS; BIOLOGICAL MARKERS; BLOOD COAGULATION; ENDOTHELIAL CELLS; HEMATOLOGY; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; VON WILLEBRAND FACTOR; WEIBEL-PALADE BODIES;

EID: 84861690050     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04718.x     Document Type: Review

References (35)

1. Weibel ER, Palade GE. New cytoplasmic components in arterial endothelia. J Cell Biol 1964; 23: 101-12.
2. Valentijn KM, Sadler JE, Valentijn JA, Voorberg J, Eikenboom J. Functional architecture of Weibel-Palade bodies. Blood 2011; 117: 5033-43.
3. Nightingale TD, White IJ, Doyle EL, Turmaine M, Harrison-Lavoie KJ, Webb KF, Cramer LP, Cutler DF. Actomyosin II contractility expels von Willebrand factor from Weibel-Palade bodies during exocytosis. J Cell Biol 2011; 194: 613-29.
4. Weibel ER, Knight BW. A morphometric study on the thickness of the pulmonary air-blood barrier. J Cell Biol 1964; 21: 367-84.
5. Palade GE. An electron microscope study of the mitochondrial structure. J Histochem Cytochem 1953; 1: 188-211.
6. Palade GE. A small particulate component of the cytoplasm. J Biophys Biochem Cytol 1955; 1: 59-68.
7. Weibel ER, Gomez DM. Architecture of the human lung. Science 1962; 137: 577-85.
8. Fuchs A, Weibel ER. Morphometrische Untersuchung der Verteilung einer spezifischen cytoplasmatischen Organelle in Endothelzellen der Ratte. Zschr Zellforsch 1966; 73: 1-9.
9. Steinsiepe KF, Weibel ER. Elektronenmikroskopische Untersuchungen an spezifischen Organellen von Endothelzellen des Frosches (Rana temporaria). Zschr Zellforsch 1970; 108: l05-26.
10. Lemeunier A, Burri PH, Weibel ER. Absence of acid phosphatase activity in specific endothelial organelles. Histochemie 1969; 20: 143-9.
11. Shimamoto T, Ishioka T. Release of a thromboplastic substance from arterial walls by epinephrine. Circ Res 1963; 12: 138-44.
12. Burri PH, Weibel ER. Beeinflussung einer spezifischen cytoplasmatischen Organelle von Endothelzellen durch Adrenalin. Zschr Zellforsch 1968; 88: 426-40.
13. Weibel ER. Morphological basis of alveolar-capillary gas exchange. Physiol Rev 1973; 53: 419-95.
14. Weibel ER, Kistler GS, Scherle WF. Practical stereological methods for morphometric cytology. J Cell Biol 1966; 30: 23-38.
15. Weibel ER, Stäubli W, Gnägi HR, Hess FA. Correlated morphometric and biochemical studies on the liver cell. I. Morphometric model, stereologic methods and normal morphometric data for rat liver. J Cell Biol 1969; 42: 68-91.
16. Hoppeler H, Lüthi P, Claassen H, Weibel ER, Howald H. The ultrastructure of the normal human skeletal muscle. A morphometric analysis on untrained men, women, and well-trained orienteers. Pfluegers Arch 1973; 344: 217-32.
17. Sengel A, Stoebner P. Golgi origin of tubular inclusions in endothelial cells. J Cell Biol 1970; 44: 223-6.
18. Parry EW, Abramovic DR. The ultrastructure of human umbilical vessel endothelium from early pregnancy to full term. J Anat 1972; 111: 29-42.
19. Jaffe EA, Nachman RL, Becker CG, Minick CR. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 1973; 52: 2745-56.
20. Gimbrone MA, Cotran RS, Folkman J. Human vascular endothelial cells in culture. J Cell Biol 1974; 60: 673-84.
21. Weibel ER, Taylor CR, Hoppeler H. The concept of symmorphosis: a testable hypothesis of structure-function relationship. Proc Natl Acad Sci USA 1991; 88: 10357-61.
22. Wagner DD, Olmsted JB, Marder VJ. Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells. J Cell Biol 1982; 95: 355-60.
23. Jaffe EA, Hoyer LW, Nachman RL. Synthesis of antihemophilic factor antigen by cultured human endothelial cells. J Clin Invest 1973; 52: 2745-56.
24. Metcalf DJ, Nightingale TD, Zenner HL, Lui-Roberts WW, Cutler DF. Formation and function of Weibel-Palade bodies. J Cell Sci 2007; 121: 19-27.
25. Wagner DD, Frenette PS. The vessel wall and its interactions. Blood 2008; 111: 5271-81.
26. Huang RH, Wang Y, Roth R, Yu X, Purvis AR, Heuser JE, Egelman EH, Sadler JE. Assembly of Weibel-Palade body-like tubules from N-terminal domains of von Willebrand factor. Proc Natl Acad Sci USA 2008; 105: 482-7.
27. Zenner HL, Collinson LM, Michaux G, Cutler DF. High-pressure freezing provides insights into Weibel-Palade body biogenesis. J Cell Sci 2007; 120: 2117-25.
28. Valentijn KM, Valentijn JA, Jansen KA, Koster AJ. A new look at Weibel-Palade body structure in endothelial cells using electron tomography. J Struct Biol 2008; 161: 447-58.
29. Michaux G, Abbitt KB, Collinson LM, Haberichter SL, Norman KE, Cutler DF. The physiological function of von Willebrand's factor depends on ist tubular shape in endothelial Weibel-Palade bodies. Dev Cell 2006; 10: 223-32.
30. Cutler DF. Fishing for platelets. Editorial. Blood 2009; 113: 1397-8.
31. Romani de Wit T, Rondaij MG, Hordijk PL, Voorberg J, van Mourik JA. Real-time imaging of the dynamics and secretory behavior of Weibel-Palade bodies. Arterioscler Thromb Vasc Biol 2003; 23: 755-61.
32. Rondaij MG, Bierings R, Kragt A, van Mourik JA, Voorberg J. Dynamics and plasticity of Weibel-Palade bodies in endothelial cells. Arterioscler Thromb Vasc Biol 2006; 26: 1002-7.
33. Andre P, Denis CV, Ware J, Saffaripour S, Hynes RO, Ruggeri ZM, Wagner DD. Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood 2000; 96: 3322-8.
34. Bonfanti R, Furie BC, Furie B, Wagner DD. PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells. Blood 1989; 73: 1109-12.
35. McEver RP, Beckstead JH, Moore KL, Marshall-Carlson L, Bainton DF. GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest 1989; 84: 92-9.