Sex differences in social interaction behaviors in rats are mediated by extracellular signal-regulated kinase 2 expression in the medial prefrontal cortex

Neuroscience

Volumn 212, Issue , 2012, Pages 86-92

  Carrier, N ^a   Kabbaj, M ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Anxiety; ERK2; Prefrontal cortex; Sex differences; Social interaction

Indexed keywords

GREEN FLUORESCENT PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BEHAVIOR CONTROL; DIESTRUS; EPIFLUORESCENCE MICROSCOPY; FEMALE; HERPES SIMPLEX VIRUS; MALE; MEDIAL PREFRONTAL CORTEX; NONHUMAN; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROESTRUS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SOCIAL INTERACTION; SOCIAL PHOBIA; WESTERN BLOTTING;

ANIMALS; ANXIETY DISORDERS; BEHAVIOR, ANIMAL; FEMALE; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; SEX CHARACTERISTICS; SOCIAL BEHAVIOR;

EID: 84861660387     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2012.03.041     Document Type: Article

References (36)

1. Alboni S., Benatti C., Capone G., Corsini D., Caggia F., Tascedda F., Mendlewicz J., Brunello N. Time-dependent effects of escitalopram on brain derived neurotrophic factor (BDNF) and neuroplasticity related targets in the central nervous system of rats. Eur J Pharmacol 2010, 643:180-187.
2. Angst J. The Zurich study. V: Anxiety and phobia in young adults. Eur Arch Psychiatry Neurol Sci 1985, 235:171-178.
3. Barabas K., Szego E.M., Kaszas A., Nagy G.M., Juhasz G.D., Abraham I.M. Sex differences in oestrogen-induced p44/42 MAPK phosphorylation in the mouse brain in vivo. J Neuroendocrinol 2006, 18:621-628.
4. Barrash J., Tranel D., Anderson S.W. Acquired personality disturbances associated with bilateral damage to the ventromedial prefrontal region. Dev Neuropsychol 2000, 18:355-381.
5. Bechara A., Damasio H., Damasio A.R., Lee G.P. Different contributions of the human amygdala and ventromedial prefrontal cortex to decision-making. J Neurosci 1999, 19:5473-5481.
6. Bruce S.E., Yonkers K.A., Otto M.W., Eisen J.L., Weisberg R.B., Pagano M., Shea M.T., Keller M.B. Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: a 12-year prospective study. Am J Psychiatry 2005, 162:1179-1187.
7. Carlezon W.A., Thome J., Olson V.G., Lane-Ladd S.B., Brodkin E.S., Hiroi N., Duman R.S., Neve R.L., Nestler E.J. Regulation of cocaine reward by CREB. Science 1998, 282:2272-2275.
8. Carrier N., Kabbaj M. Erk2 signaling in the hippocampus mediates the antidepressant effects of testosterone. Biol Psychiatry 2012.
9. Cheng J., Watkins S.C., Walker W.H. Testosterone activates mitogen-activated protein kinase via Src kinase and the epidermal growth factor receptor in sertoli cells. Endocrinology 2007, 148:2066-2074.
10. Cuffe J.S., Dickinson H., Simmons D.G., Moritz K.M. Sex specific changes in placental growth and MAPK following short term maternal dexamethasone exposure in the mouse. Placenta 2011, 32:981-989.
11. Duman C.H., Schlesinger L., Kodama M., Russell D.S., Duman R.S. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatry 2007, 61:661-670.
12. English J.D., Sweatt J.D. A requirement for the mitogen-activated protein kinase cascade in hippocampal long term potentiation. J Biol Chem 1997, 272:19103-19106.
13. File S.E., Hyde J.R. Can social interaction be used to measure anxiety?. Br J Pharmacol 1978, 62:19-24.
14. Guzowski J.F., Lyford G.L., Stevenson G.D., Houston F.P., McGaugh J.L., Worley P.F., Barnes C.A. Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 2000, 20:3993-4001.
15. Hollis F., Duclot F., Gunjan A., Kabbaj M. Individual differences in the effect of social defeat on anhedonia and histone acetylation in the rat hippocampus. Horm Behav 2010, 59:331-337.
16. Johnston A.L., File S.E. Sodium phenobarbitone reverses the anxiogenic effects of compounds acting at three different central sites. Neuropharmacology 1989, 28:83-88.
17. Johnston A.L., File S.E. Sex differences in animal tests of anxiety. Physiol Behav 1991, 49:245-250.
18. Kessler R.C., Chiu W.T., Demler O., Merikangas K.R., Walters E.E. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005, 62:617-627.
19. Kessler R.C., McGonagle K.A., Zhao S., Nelson C.B., Hughes M., Eshleman S., Wittchen H.U. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry 1994, 51:8-19.
20. Khachigian L.M. Inducible expression of Egr-1-dependent genes. A paradigm of transcriptional activation in vascular endothelium. Circ Res 1997, 81:457-461.
21. Krishnan V., Han M.H., Graham D.L., Berton O., Renthal W., Russo S.J., Laplant Q., Graham A., Lutter M., Lagace D.C., Ghose S., Reister R., Tannous P., Green T.A., Neve R.L., Chakravarty S., Kumar A., Eisch A.J., Self D.W., Lee F.S., Tamminga C.A., Cooper D.C., Gershenfeld H.K., Nestler E.J. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell 2007, 131:391-404.
22. Meller E., Shen C., Nikolao T.A., Jensen C., Tsimberg Y., Chen J., Gruen R.J. Region-specific effects of acute and repeated restraint stress on the phosphorylation of mitogen-activated protein kinases. Brain Res 2003, 979:57-64.
23. Migliaccio A., Castoria G., Di Domenico M., de Falco A., Bilancio A., Lombardi M., Barone M.V., Ametrano D., Zannini M.S., Abbondanza C., Auricchio F. Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation. EMBO J 2000, 19:5406-5417.
24. Osawa M., Itoh S., Ohta S., Huang Q., Berk B.C., Marmarosh N.L., Che W., Ding B., Yan C., Abe J. ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation. J Biol Chem 2004, 279:29691-29699.
25. Paxinos G.W.C. The rat brain in stereotaxic coordinates 1998, Academic Press, San Diego.
26. Pereira A., Sugiharto-Winarno A., Zhang B., Malcolm P., Fink G., Sundram S. Clozapine induction of ERK1/2 cell signalling via the EGF receptor in mouse prefrontal cortex and striatum is distinct from other antipsychotic drugs. Int J Neuropsychopharmacol 2011, 1-12.
27. Qi X., Lin W., Li J., Li H., Wang W., Wang D., Sun M. Fluoxetine increases the activity of the ERK-CREB signal system and alleviates the depressive-like behavior in rats exposed to chronic forced swim stress. Neurobiol Dis 2008, 31:278-285.
28. Qi X., Lin W., Li J., Pan Y., Wang W. The depressive-like behaviors are correlated with decreased phosphorylation of mitogen-activated protein kinases in rat brain following chronic forced swim stress. Behav Brain Res 2006, 175:233-240.
29. Regier D.A., Narrow W.E., Rae D.S. The epidemiology of anxiety disorders: the epidemiologic catchment area (ECA) experience. J Psychiatr Res 1990, 24(Suppl. 2):3-14.
30. Russo S.J., Bolanos C.A., Theobald D.E., DeCarolis N.A., Renthal W., Kumar A., Winstanley C.A., Renthal N.E., Wiley M.D., Self D.W., Russell D.S., Neve R.L., Eisch A.J., Nestler E.J. IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates. Nat Neurosci 2007, 10:93-99.
31. Shen C.P., Tsimberg Y., Salvadore C., Meller E. Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions. BMC Neurosci. 2004, 5:36.
32. Silverman E.S., Collins T. Pathways of Egr-1-mediated gene transcription in vascular biology. Am J Pathol 1999, 154:665-670.
33. Slamberova R., Mikulecka A., Pometlova M., Schutova B., Hruba L., Deykun K. Sex differences in social interaction of methamphetamine-treated rats. Behav Pharmacol 2011, 22:617-623.
34. Stack A., Carrier N., Dietz D., Hollis F., Sorenson J., Kabbaj M. Sex differences in social interaction in rats: role of the immediate-early gene zif268. Neuropsychopharmacology 2010, 35:570-580.
35. Sweatt J.D. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 2001, 76:1-10.
36. Xia Z., Dudek H., Miranti C.K., Greenberg M.E. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 1996, 16:5425-5436.