Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?

Experimental Eye Research

Volumn 99, Issue 1, 2012, Pages 48-54

  Truscott, Roger J W ^a,f   Mizdrak, Jasminka ^a   Friedrich, Michael G ^a   Hooi, Michelle Y ^a   Lyons, Brian ^a   Jamie, Joanne F ^b   Davies, Michael J ^c,d   Wilmarth, Phillip A ^e   David, Larry L ^e  

^a UNIVERSITY OF SYDNEY   (Australia)

^b MACQUARIE UNIVERSITY   (Australia)

^c HEART RESEARCH INSTITUTE   (Australia)

^d University of Sydney   (Australia)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f UNIVERSITY OF WOLLONGONG   (Australia)

Author keywords

Age; Lens protein; Methylation; Post translational modification

Indexed keywords

CRYSTALLIN; CYSTEINE; HISTIDINE; LENS PROTEIN; S ADENOSYLMETHIONINE; TRYPSIN;

ADOLESCENT; ADULT; AGED; ALKYLATION; ARTICLE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LENS; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN METHYLATION; PROTEIN MODIFICATION;

ADOLESCENT; ADULT; AGED; AGING; BETA-CRYSTALLIN A CHAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; HISTIDINE; HUMANS; LENS, CRYSTALLINE; MASS SPECTROMETRY; METHYLATION; MIDDLE AGED; PROTEIN METHYLTRANSFERASES; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; S-ADENOSYLMETHIONINE; TISSUE DONORS; YOUNG ADULT;

EID: 84861660221     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2012.04.002     Document Type: Article

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