Cardiomegaly is a common arrhythmogenic substrate in adult sudden cardiac deaths, and is associated with obesity

Pathology

Volumn 44, Issue 3, 2012, Pages 187-191

  Tavora, Fabio ^a   Zhang, Y ^b   Zhang, M ^b   Li, L ^b   Ripple, M ^c   Fowler, D ^b   Burke, Allen ^a,b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

Cardiomyopathy; Sudden death

Indexed keywords

EID: 84861625003     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0b013e3283513f54     Document Type: Article

References (40)

1. Chugh SS, Jui J, Gunson K, et al. Current burden of sudden cardiac death: multiple source surveillance versus retrospective death certificate-based review in a large US community. J Am Coll Cardiol 2004; 44: 1268-75. (Pubitemid 39208884)
2. Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease and stroke statistics - 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009; 119: 480-6.
3. Duflou J, Virmani R, Rabin I, Burke A, Farb A, Smialek J. Sudden death as a result of heart disease in morbid obesity. Am Heart J 1995; 130: 306-13.
4. Contaldo F, Pasanisi F, Finelli C, de Simone G. Obesity, heart failure and sudden death. Nutr Metab Cardiovasc Dis 2002; 12: 190-7. (Pubitemid 135713170)
5. Gradman AH, Alfayoumi F. From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease. Prog Cardiovasc Dis 2006; 48: 326-41.
6. Hunt SA. ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure). J Am Coll Cardiol 2005; 46: e1-82.
7. Wong C, Marwick TH. Obesity cardiomyopathy: pathogenesis and patho-physiology. Nat Clin Pract Cardiovasc Med 2007; 4: 436-43.
8. Owan T, Litwin SE. Is there a cardiomyopathy of obesity? Curr Heart Fail Rep 2007; 4: 221-8.
9. Wong C, Marwick TH. Obesity cardiomyopathy: diagnosis and therapeutic implications. Nat Clin Pract Cardiovasc Med 2007; 4: 480-90. (Pubitemid 47321548)
10. Murphy NF, MacIntyre K, Stewart S, Hart CL, Hole D, McMurray JJ. Long-term cardiovascular consequences of obesity: 20-year follow-up of more than 15000 middle-aged men and women (the Renfrew-Paisley study). Eur Heart J 2006; 27: 96-106. (Pubitemid 41785938)
11. Haque AK, Gadre S, Taylor J, Haque SA, Freeman D, Duarte A. Pulmonary and cardiovascular complications of obesity: an autopsy study of 76 obese subjects. Arch Pathol Lab Med 2008; 132: 1397-404.
12. Kitzman DW, Scholz DG, Hagen PT, Ilstrup DM, Edwards WD. Age-related changes in normal human hearts during the first 10 decades of life. Part II (Maturity): A quantitative anatomic study of 765 specimens from subjects 20 to 99 years old. Mayo Clin Proc 1988; 63: 137-46. (Pubitemid 18064283)
13. Tracy R, Mercante D, Moncada A, Berenson G. Quantitation of hypertensive nephrosclerosis on an objective rational scale of measure in adults and children. Am J Clin Pathol 1986; 85: 312-8. (Pubitemid 16071217)
14. Gallagher PJ. The pathological investigation of sudden cardiac death. Curr Diagn Pathol 2007; 13: 366-74. (Pubitemid 47379547)
15. Subirana MT, Juan-Babot JO, Puig T, et al. Specific characteristics of sudden death in a mediterranean Spanish population. Am J Cardiol 2011; 107: 622-7.
16. Fornes P, Lecomte D, Nicolas G. Sudden out-of-hospital coronary death in patients with no previous cardiac history. An analysis of 221 patients studied at autopsy. J Forensic Sci 1993; 38: 1084-91. (Pubitemid 23280205)
17. Azmak AD. Sudden natural deaths in Edirne, Turkey, from 1984 to 2005. Med Sci Law 2007; 47: 147-55.
18. Basso C, Burke M, Fornes P, et al. Guidelines for autopsy investigation of sudden cardiac death. Virchows Arch 2008; 452: 11-8.
19. Basso C, Calabrese F, Corrado D, Thiene G. Postmortem diagnosis in sudden cardiac death victims: macroscopic, microscopic and molecular findings. Cardiovasc Res 2001; 50: 290-300. (Pubitemid 32382156)
20. Bowker TJ, Wood DA, Davies MJ, et al. Sudden, unexpected cardiac or unexplained death in England: a national survey. QJM 2003; 96: 269-79. (Pubitemid 36432386)
21. Burke AP, Farb A, Virmani R, Goodin J, Smialek JE. Sports-related and nonsports-related sudden cardiac death in young adults. Am Heart J 1991; 121: 568-75.
22. Eckart RE, Scoville SL, Campbell CL, et al. Sudden death in young adults: a 25-year review of autopsies in military recruits. Ann Intern Med 2004; 141: 829-34. (Pubitemid 39601175)
23. Gwynne JF. Sudden cardiac death in Otago: a review of 408 cases. N Z Med J 1983; 96: 415-7. (Pubitemid 13014465)
24. Maron BJ, Shirani J, Poliac LC, Mathenge R, Roberts WC, Mueller FO. Sudden death in young competitive athletes. Clinical, demographic, and pathological profiles. JAMA 1996; 276: 199-204. (Pubitemid 26235063)
25. Omae T, Ueda K, Hasuo Y, Tanaka K. Sudden unexpected deaths in a Japanese community - Hisayama study. Jpn Circ J 1983; 47: 554-61. (Pubitemid 13044199)
26. Penttila A. Sudden and unexpected natural deaths of adult males. An analysis of 799 forensic autopsies in 1976. Forensic Sci Int 1980; 16: 249-59. (Pubitemid 11210762)
27. Burke AP, Farb A, Liang YH, Smialek J, Virmani R. Effect of hypertension and cardiac hypertrophy on coronary artery morphology in sudden cardiac death. Circulation 1996; 94: 3138-45. (Pubitemid 26427479)
28. Arbustini E, Grasso M, Diegoli M, et al. Coronary thrombosis in non-cardiac death. Coron Artery Dis 1993; 4: 751-9. (Pubitemid 23297396)
29. Davies MJ. Anatomic features in victims of sudden coronary death. Coronary artery pathology. Circulation 1992; 85 (1 Suppl): I19-24.
30. Warnes CA, Roberts WC. Sudden coronary death: relation of amount and distribution of coronary narrowing at necropsy to previous symptoms of myocardial ischemia, left ventricular scarring and heart weight. Am J Cardiol 1984; 54: 65-73. (Pubitemid 14085351)
31. Suvarna S, Soilleux EJ. Adult sudden cardiac death: audit of 5 years of non-hypertensive, non-ischaemic causes and autopsy reports. Histopathology 2009; 54: 381-4.
32. Maron BJ, Towbin JA, Thiene G, et al. Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 2006; 113: 1807-16. (Pubitemid 43958474)
33. Felker GM, Hu W, Hare JM, Hruban RH, Baughman KL, Kasper EK. The spectrum of dilated cardiomyopathy. The Johns Hopkins experience with 1278 patients. Medicine (Baltimore) 1999; 78: 270-83. (Pubitemid 29343203)
34. Burke AP, Farb A, Pestaner J, et al. Traditional risk factors and the incidence of sudden coronary death with and without coronary thrombosis in blacks. Circulation 2002; 105: 419-24. (Pubitemid 34141696)
35. Szczepaniak LS, Victor RG, Orci L, Unger RH. Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America. Circ Res 2007; 101: 759-67. (Pubitemid 350287190)
36. Ristow B, Rabkin J, Haeusslein E. Improvement in dilated cardiomyopathy after bariatric surgery. J Card Fail 2008; 14: 198-202. (Pubitemid 351434596)
37. Burke AP, Farb A, Malcom GT, Liang Y, Smialek JE, Virmani R. Plaque rupture and sudden death related to exertion in men with coronary artery disease. JAMA 1999; 281: 921-6. (Pubitemid 29124636)
38. Ito H, Yeo KK, Wijetunga M, Seto TB, Tay K, Schatz IJ. A comparison of echocardiographic findings inyoung adults with cardiomyopathy: With and without a history of methamphetamine abuse. Clin Cardiol 2009; 32: E18-22.
39. Kouno A, Matoba R, Shikata I. A statistical study of sudden cardiac death for past five years in Osaka medical, investigated at the Osaka Medical Examiner's Office. Acta Med Leg Soc (Liege) 1989; 39: 205-15.
40. Loire R, Tabib A. Unexpected sudden cardiac death. An evaluation of 1000 autopsies. Arch Mal Coeur Vaiss 1996; 89: 13-8.