Influence of lymphatic invasion on locoregional recurrence following mastectomy: Indication for postmastectomy radiotherapy for breast cancer patients with one to three positive nodes

International Journal of Radiation Oncology Biology Physics

Volumn 83, Issue 3, 2012, Pages 845-852

  Matsunuma, Ryoichi ^a,b   Oguchi, Masahiko ^a   Fujikane, Tomoko ^a   Matsuura, Masaaki ^c   Sakai, Takehiko ^a   Kimura, Kiyomi ^a   Morizono, Hidetomo ^a   Iijima, Kotaro ^a   Izumori, Ayumi ^a   Miyagi, Yumi ^a   Nishimura, Seiichiro ^a   Makita, Masujiro ^a   Gomi, Naoya ^a   Horii, Rie ^a   Akiyama, Futoshi ^c   Iwase, Takuji ^a  

^a CANCER INSTITUTE HOSPITAL   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

Breast cancer; Lymphatic invasion; Postmastectomy radiotherapy

Indexed keywords

BREAST CANCER; LOCAL THERAPY; LOCOREGIONAL RECURRENCE; LYMPHATIC INVASION; MULTI VARIATE ANALYSIS; NODE-POSITIVE; POSITIVE LYMPH NODES; POSTMASTECTOMY RADIOTHERAPY; POSTOPERATIVE RADIOTHERAPY; RETROSPECTIVE ANALYSIS;

BODY FLUIDS; DISEASES; STATISTICAL TESTS;

RADIOTHERAPY;

ADULT; ARTICLE; BREAST CANCER; CANCER INVASION; CANCER LOCALIZATION; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; HUMAN; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MASTECTOMY; POSTMASTECTOMY RADIOTHERAPY; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

AGE FACTORS; AXILLA; BREAST NEOPLASMS; FEMALE; HUMANS; LYMPH NODES; LYMPHATIC METASTASIS; MASTECTOMY; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; POSTOPERATIVE PERIOD; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; RETROSPECTIVE STUDIES; TUMOR BURDEN;

EID: 84861620945     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.08.029     Document Type: Article

References (20)

1. B. Fisher, N.H. Slack, and P.J. Cavanaugh Postoperative radiotherapy in the treatment of breast cancer: Results of the NSABP Clinical Trial Ann Surg 172 1970 711 732
2. M. Overgaard, P.S. Hansen, and J. Overgaard Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy: Danish Breast Cancer Cooperative Group 82b Trial N Engl J Med 337 1997 949 955
3. J. Ragaz, S.M. Jackson, and N. Le Adjuvant radiotherapy and chemotherapy in node-positive women with breast cancer N Engl J Med 337 1997 956 962
4. M. Overgaard, M.B. Jensen, and J. Overgaard Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomized trial Lancet 353 1999 1641 1648
5. M. Clarke, R. Collins, and S. Darby Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomized trials Lancet 366 2005 2087 2106
6. J. Ragaz, I.A. Olivotto, and J.J. Spinelli Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial J Natl Cancer Inst 97 2005 116 126
7. Early Breast Cancer Trialists' Collaborative Group Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: An overview of the randomized trials Lancet 355 2000 1757 1770
8. T.J. Whelan, J. Julian, and J. Wright Does locoregional radiation therapy improve survival in breast cancer? A meta-analysis J Clin Oncol 18 2000 1220 1229
9. A. Recht, S.B. Edge, and L.J. Solin Postmastectomy radiotherapy: Clinical practice guidelines of the American Society of Clinical Oncology J Clin Oncol 19 2001 1539 1569
10. T.B. Bevers, B.O. Anderson, and E. Bonaccio NCCN clinical practice guidelines in oncology: breast cancer screening and diagnosis J Natl Compr Canc Netw 2009 1060 1096
11. M. Overgaard, H.M. Nielsen, and J. Overgaard Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82b and c randomized trials Radiother Oncol 82 2007 247 253
12. A. Taghian, J.-H. Jeong, and E. Mamounas Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: Results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials J Clin Oncol 22 2004 4247 4254
13. P.T. Truong, I.A. Olivotto, and T.J. Whelan Clinical practice guidelines for the care and treatment of breast cancer. 16. Locoregional post-mastectomy radiotherapy CMAJ 170 2004 1263 1273
14. L.J. Pierce The use of radiotherapy after mastectomy: A review of the literature J Clin Oncol 23 2005 1706 1717
15. K.C. Lee, R.A. DeLelis, and M.L. Silverman Prognostic significance of peritumoral lymphatic and blood vessel invasion in node-negative carcinoma of the breast J Clin Oncol 8 1990 1457 1465
16. R. Jagsi, R.A. Raad, and S. Goldberg Locoregional recurrence rates and prognostic factors for failure in node-negative patients treated with mastectomy: Implications for postmastectomy radiation Int J Radiat Oncol Biol Phys 62 2005 1035 1039
17. A. Taghian, J.-H. Jeong, and E. Mamounas Low locoregional recurrence rate among node-negative breast cancer patients with 5cm or larger treated by mastectomy, with or without adjuvant systemic therapy and without radiotherapy: Results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials J Clin Oncol 24 2006 3927 3932
18. K.L. Griem, I.C. Henderson, and R. Gelman The 5-year results of a randomized trial of adjuvant radiation therapy after chemotherapy in breast cancer patients treated with mastectomy J Clin Oncol 5 1987 1546 1555
19. A. Recht, R. Gray, and N.E. Davidson Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: Experience of the Eastern Cooperative Oncology Group J Clin Oncol 17 1999 1689 1700
20. P.P. Rosen Tumor emboli in intramammary lymphatics in breast carcinoma: Pathologic criteria for diagnosis and clinical significance. Part 2 Pathol Ann 18 1983 215 232