The role of premorbid personality and cognitive factors in awareness of illness, memory, and behavioural functioning in Alzheimer's disease

Cognitive Neuropsychiatry

Volumn 17, Issue 3, 2012, Pages 227-245

  Gilleen, J ^a   Greenwood, K ^b   Archer, N ^a   Lovestone, S ^a   David, A S ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Alzheimer's disease; Awareness; Cognition; Dementia; Insight; Personality

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; AWARENESS; BECK COGNITIVE INSIGHT SCALE; BECK DEPRESSION INVENTORY; BEHAVIOR DISORDER; BRIEF PSYCHIATRIC RATING SCALE; CAREGIVER BURDEN; CLINICAL ARTICLE; COGNITION; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMOGRAPHY; DISEASE CLASSIFICATION; DISEASE SEVERITY; EXTRAVERSION; FEMALE; HUMAN; MALE; MEMORY; MEMORY AWARENESS RATING SCALE; METHODOLOGY; MINI MENTAL STATE EXAMINATION; MOOD; NEUROSIS; NEUROTICISM-EXTROVERSION-OPENNESS FIVE-FACTOR INVENTORY; ONSET AGE; PATIENT COMPETENCY RATING SCALE; PERSONALITY; PERSONALITY TEST; PREDICTOR VARIABLE; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; SCALE FOR THE UNAWARENESS OF MENTAL DISORDER; WECHSLER INTELLIGENCE SCALE;

AFFECT; AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AWARENESS; COGNITION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MEMORY; NEUROPSYCHOLOGICAL TESTS; PERSONALITY; PERSONALITY INVENTORY; SELF CONCEPT; SEVERITY OF ILLNESS INDEX;

EID: 84861598389     PISSN: 13546805     EISSN: 14640619     Source Type: Journal    
DOI: 10.1080/13546805.2011.588007     Document Type: Article

References (47)

1. Amador, X. F., Strauss, D. H., Yale, S. A., Flaum, M. M., Endicott, J., and, Gorman, J. M. 1993. Assessment of insight in psychosis. American Journal of Psychiatry, 150 (6): 873-879. (Pubitemid 23156765)
2. Archer, N., Brown, R. G., Boothby, H., Foy, C., Nicholas, H., and, Lovestone, S. 2006. The NEO-FFI is a reliable measure of premorbid personality in patients with probable Alzheimer's disease. International Journal of Geriatric Psychiatry, 21 (5): 477-484.
3. Bach, L., and, David, A. 2006. Self-awareness after acquired and traumatic brain injury. Neuropsychological Rehabilitation, 16 (4): 397-414. (Pubitemid 44174481)
4. Beck, A. T., Baruch, E., Balter, J. M., Steer, R. A., and, Warman, D. M. 2004. A new instrument for measuring insight: The Beck Cognitive Insight Scale. Schizophrenia Research, 68 (2-3): 319-329. (Pubitemid 38526153)
5. Beck, A. T., Steer, R. A., Ball, R., and, Ranieri, W. 1996. Comparison of Beck Depression Inventories-IA and-II in psychiatric outpatients. Journal of Personal Assessment, 67 (3): 588-597. (Pubitemid 26382973)
6. Chatterjee, A., Strauss, M. E., Smyth, K. A., and, Whitehouse, P. J. 1992. Personality changes in Alzheimer's disease. Archives of Neurology, 49 (5): 486-491.
7. Clare, L., Wilson, B. A., Carter, G., Roth, I., and, Hodges, J. R. 2002. Assessing awareness in early-stage Alzheimer's disease: Development and piloting of the Memory Awareness Rating Scale. Neuropsychological Rehabilitation, 12 (4): 341-362. (Pubitemid 35006180)
8. Costa, P. T., and, McCrae, R. R. 1992. Normal personality assessment in clinical practice: The NEO Personality Inventory. Psychological Assessment, 4 (1): 5-13.
9. DeBettignies, B. H., Mahurin, R. K., and, Pirozzolo, F. J. 1990. Insight for impairment in independent living skills in Alzheimer's disease and multi-infarct dementia. Journal of Clinical and Experimental Neuropsychology, 12 (2): 355-363. (Pubitemid 20203703)
10. Derouesne, C., Thibault, S., Lagha-Pierucci, S., Baudouin-Madec, V., Ancri, D., and, Lacomblez, L. 1999. Decreased awareness of cognitive deficits in patients with mild dementia of the Alzheimer type. International Journal of Geriatric Psychiatry, 14 (12): 1019-1030. (Pubitemid 30066036)
11. Dixon, R. A. 1989. Questionnaire research on metamemory and aging: Issues of structure and function. In Everyday cognition in adulthood and late life, Edited by: Poon, L. W., Rubin, D. C. and Wilson, B. A. 394-415. Cambridge, UK: Cambridge University Press.
12. Ecklund-Johnson, E., and, Torres, I. 2005. Unawareness of deficits in Alzheimer's disease and other dementias: Operational definitions and empirical findings. Neuropsychological Review, 15 (3): 147-166. (Pubitemid 41674442)
13. Folstein, M. F., Folstein, S. E., and, McHugh, P. R. 1975. Mini-Mental State: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12 (3): 189-198.
14. Fordyce, D. J., and, Roueche, J. R. 1986. Changes in perspectives of disability among patients, staff, and relatives during rehabilitation of brain injury. Rehabilitation Psychology, 31: 217-229. (Pubitemid 17010148)
15. Gauthier, L., Dehaut, F., and, Joanette, Y. 1989. The Bells Test: A quantitative and qualitative test for visual neglect. International Journal of Clinical Neuropsychology, 11 (2): 49-54. (Pubitemid 19208934)
16. Green, J. G., Smith, M., Gardiner, M., and, Timbury, G. L. 1982. Measuring behavioral disturbance of elderly demented patients in the community and its effects on relatives: A factor analytic study. Age and Ageing, 11: 121-126. (Pubitemid 12102597)
17. Harwood, D. G., Sultzer, D. L., Feil, D., Monserratt, L., Freedman, E., and, Mandelkern, M. A. 2005. Frontal lobe hypometabolism and impaired insight in Alzheimer disease. American Journal of Geriatric Psychiatry, 13 (11): 934-941. (Pubitemid 46638659)
18. Kemp, R., and, David, A. 1997. Insight and compliance. In Treatment compliance and the therapeutic alliance, Edited by: Blackwell, B. 61-84. Amsterdam, The Netherlands: Harwood Academic Publishers.
19. Koltai, D. C., Welsh-Bohmer, K. A., and, Schmechel, D. E. 2001. Influence of anosognosia on treatment outcome among dementia patients. Neuropsychological Rehabilitation, 11 (3): 455-475. (Pubitemid 32662028)
20. Lopez, O. L., Becker, J. T., Somsak, D., Dew, M. A., and, DeKosky, S. T. 1994. Awareness of cognitive deficits and anosognosia in probable Alzheimer's disease. European Neurology, 34 (5): 277-282. (Pubitemid 24265499)
21. Lukoff, D., Nuechterlein, K. H., and, Ventura, J. 1986. Manual for the Expanded Brief Psychiatric Rating Scale. Schizophrenia Bulletin, 12: 594-602.
22. Mangone, C. A., Hier, D. B., Gorelick, P. B., Ganellen, R. J., Langenberg, P., Boarman, R., and, Dollear, W. C. 1991. Impaired insight in Alzheimer's disease. Journal of Geriatric Psychiatry and Neurology, 4 (4): 189-193.
23. Markova, I. S. 2005. Insight in psychiatry, Cambridge, UK: Cambridge University Press.
24. McGlynn, S. M., and, Schacter, D. L. 1989. Unawareness of deficits in neuropsychological syndromes. Journal of Clinical and Experimental Neuropsychology, 11 (2): 143-205.
25. McKhann, G. 1984. Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology, 34 (7): 939-944. (Pubitemid 14076461)
26. Michon, A., Deweer, B., Pillon, B., Agid, Y., and, Dubois, B. 1994. Relation of anosognosia to frontal lobe dysfunction in Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry, 57 (7): 805-809. (Pubitemid 24214960)
27. Nelson, H. E., and, Willison, J. 1991. National Adult Reading Test (NART): Test manual, 2nd ed., Windsor, UK: NFER Nelson.
28. Psychological Corporation. 1999. Wechsler Abbreviated Scale of Intelligence (WASI) manual. San Antonio, TX: Psychological Corporation.
29. Rankin, K. P., Baldwin, E., Pace-Savitsky, C., Kramer, J. H., and, Miller, B. L. 2005. Self awareness and personality change in dementia. Journal of Neurology, Neurosurgery and Psychiatry, 76 (5): 632-639. (Pubitemid 40569671)
30. Reed, B. R., Jagust, W. J., and, Coulter, L. 1993. Anosognosia in Alzheimer's disease: Relationships to depression, cognitive function, and cerebral perfusion. Journal of Clinical and Experimental Neuropsychology, 15 (2): 231-244. (Pubitemid 23156209)
31. Reitan, R. M., and, Wolfson, D. 1985. The Halstead-Reitan Neuropsychological Test Battery: Theory and clinical interpretation, Tucson, AZ: Neuropsychology Press.
32. Seiffer, A., Clare, L., and, Harvey, R. 2005. The role of personality and coping style in relation to awareness of current functioning in early-stage dementia. Aging and Mental Health, 9 (6): 535-541. (Pubitemid 41546051)
33. Seltzer, B., Vasterling, J. J., Mathias, C. W., and, Brennan, A. 2001. Clinical and neuropsychological correlates of impaired awareness of deficits in Alzheimer disease and Parkinson disease: A comparative study. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 14 (2): 122-129. (Pubitemid 32549937)
34. Seltzer, B., Vasterling, J. J., Yoder, J. A., and, Thompson, K. A. 1997. Awareness of deficit in Alzheimer's disease: Relation to caregiver burden. The Gerontologist, 37 (1): 20-24. (Pubitemid 27083813)
35. Sevush, S., and, Leve, N. 1993. Denial of memory deficit in Alzheimer's disease. American Journal of Psychiatry, 150 (5): 748-751. (Pubitemid 23137680)
36. Siegler, I. C., Dawson, D. V., and, Welsh, K. A. 1994. Caregiver ratings of personality change in Alzheimer's disease patients: A replication. Psychology and Aging, 9 (3): 464-466. (Pubitemid 24301679)
37. Siegler, I. C., Welsh, K. A., Dawson, D. V., Fillenbaum, G. G., Earl, N. L., and, Kaplan, E. B. 1991. Ratings of personality change in patients being evaluated for memory deficits. Alzheimer Disease & Associated Disorders, 5: 240-250.
38. Spreen, O., and, Benton, A. L. 1977. Neurosensory Center Comprehensive Examination for Aphasia (NCCEA), Victoria, Canada: University of Victoria Neuropsychology Laboratory.
39. Strauss, M. E., Pasupathi, M., and, Chatterjee, A. 1993. Concordance between observers in descriptions of personality change in Alzheimer's disease. Psychology and Aging, 8 (4): 475-480.
40. Talassi, E., Cipriani, G., Bianchetti, A., and, Trabucchi, M. 2007. Personality changes in Alzheimer's disease. Aging and Mental Health, 11 (5): 526-531. (Pubitemid 47450795)
41. Vasterling, J. J., Seltzer, B., Foss, J. W., and, Vanderbrook, V. 1995. Unawareness of deficit in Alzheimer's disease: Domain-specific differences and disease correlates. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 8 (1): 26-32.
42. Verhey, F. R. J., Rozendaal, N., Ponds, R., and, Jolles, J. 1993. Dementia, awareness and depression. International Journal of Geriatric Psychiatry, 8 (10): 851-856. (Pubitemid 23297364)
43. Weinstein, E. A., Friedland, R. P., and, Wagner, E. E. 1994. Denial/unawareness of impairment and symbolic behavior in Alzheimer's disease. Neuropsychiatry, Neuropsychology and Behavioral Neurology, 7 (3): 176-184. (Pubitemid 24268941)
44. Weinstein, E. A., and, Kahn, R. L. 1953. Personality factors in denial of illness. Archives of Neurology and Psychiatry, 69 (3): 355-367.
45. Welleford, E. A., Harkins, S. W., and, Taylor, J. R. 1995. Personality change in dementia of the Alzheimer's type: Relations to caregiver personality and burden. Experimental Aging Research, 21 (3): 295-314.
46. Wilson, B., Cockburn, J., and, Baddeley, A. 1985. The Rivermead Behavioural Memory Test (RBMT), Reading, UK: Thames Valley Test Co.
47. Wilson, B. A., &, Thames Valley Test Company. 1996. BADS: Behavioural Assessment of the Dysexecutive Syndrome. Reading, UK: Thames Valley Test Co.