Increased matrix metalloproteinase-9 activity and mRNA expression in lung injury following cardiopulmonary bypass

Laboratory Investigation

Volumn 92, Issue 6, 2012, Pages 910-916

  Wang, Changtian ^a   Li, Demin ^a   Qian, Yajun ^a   Wang, Jun ^a   Jing, Hua ^a  

^a MEDICAL SCHOOL OF NANJING UNIVERSITY   (China)

Author keywords

acute lung injury; cardiopulmonary bypass; doxycycline; matrix metalloproteinases 9; protective effect; rat model; tissue inhibitor of metalloproteinase 1

Indexed keywords

GELATINASE B; MESSENGER RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANNULATION; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; HEPARINIZATION; HISTOLOGY; LUNG EDEMA; LUNG LAVAGE; LUNG STRUCTURE; MALE; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; WESTERN BLOTTING;

ACUTE LUNG INJURY; ANIMALS; ANTI-BACTERIAL AGENTS; BRONCHOALVEOLAR LAVAGE FLUID; CARDIOPULMONARY BYPASS; DISEASE MODELS, ANIMAL; DOXYCYCLINE; DRUG ADMINISTRATION SCHEDULE; GENE EXPRESSION REGULATION; LEUKOCYTE COUNT; MALE; MATRIX METALLOPROTEINASE 9; NEUTROPHILS; PULMONARY EDEMA; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASE-1;

EID: 84861592247     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2012.50     Document Type: Article

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