-
1
-
-
0031854558
-
The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review)
-
To CT, Tsao MS,. The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review). Oncol Rep 1998; 5: 1013-24.
-
(1998)
Oncol Rep
, vol.5
, pp. 1013-1024
-
-
To, C.T.1
Tsao, M.S.2
-
2
-
-
0027830892
-
Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells
-
Gherardi E, Sharpe M, Lane K, Sirulnik A, Stoker M,. Hepatocyte growth factor/scatter factor (HGF/SF), the c-met receptor and the behaviour of epithelial cells. Symp Soc Exp Biol 1993; 47: 163-81.
-
(1993)
Symp Soc Exp Biol
, vol.47
, pp. 163-181
-
-
Gherardi, E.1
Sharpe, M.2
Lane, K.3
Sirulnik, A.4
Stoker, M.5
-
3
-
-
0022472582
-
Mechanism of met oncogene activation
-
Park M, Dean M, Cooper CS, Schmidt M, O'Brien SJ, Blair DG, Vande Woude GF,. Mechanism of met oncogene activation. Cell 1986; 45: 895-904.
-
(1986)
Cell
, vol.45
, pp. 895-904
-
-
Park, M.1
Dean, M.2
Cooper, C.S.3
Schmidt, M.4
O'Brien, S.J.5
Blair, D.G.6
Vande Woude, G.F.7
-
4
-
-
13944276728
-
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer
-
Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, Richards W, Sugarbaker D, et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res 2005; 65: 1479-88.
-
(2005)
Cancer Res
, vol.65
, pp. 1479-1488
-
-
Ma, P.C.1
Jagadeeswaran, R.2
Jagadeesh, S.3
Tretiakova, M.S.4
Nallasura, V.5
Fox, E.A.6
Hansen, M.7
Schaefer, E.8
Naoki, K.9
Lader, A.10
Richards, W.11
Sugarbaker, D.12
-
5
-
-
33745697763
-
Targeting the c-Met signaling pathway in cancer
-
Peruzzi B, Bottaro DP,. Targeting the c-Met signaling pathway in cancer. Clin Cancer Res 2006; 12: 3657-60.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3657-3660
-
-
Peruzzi, B.1
Bottaro, D.P.2
-
6
-
-
0034693753
-
Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
-
Furge KA, Zhang YW, Vande Woude GF,. Met receptor tyrosine kinase: enhanced signaling through adapter proteins. Oncogene 2000; 19: 5582-89.
-
(2000)
Oncogene
, vol.19
, pp. 5582-5589
-
-
Furge, K.A.1
Zhang, Y.W.2
Vande Woude, G.F.3
-
7
-
-
34547558390
-
Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: Implications for tumour invasion
-
Ma PC, Tretiakova MS, Nallasura V, Jagadeeswaran R, Husain AN, Salgia R,. Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion. Br J Cancer 2007; 97: 368-77.
-
(2007)
Br J Cancer
, vol.97
, pp. 368-377
-
-
Ma, P.C.1
Tretiakova, M.S.2
Nallasura, V.3
Jagadeeswaran, R.4
Husain, A.N.5
Salgia, R.6
-
8
-
-
34247465448
-
C-Met is a potentially new therapeutic target for treatment of human melanoma
-
Puri N, Ahmed S, Janamanchi V, Tretiakova M, Zumba O, Krausz T, Jagadeeswaran R, Salgia R,. c-Met is a potentially new therapeutic target for treatment of human melanoma. Clin Cancer Res 2007; 13: 2246-53.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2246-2253
-
-
Puri, N.1
Ahmed, S.2
Janamanchi, V.3
Tretiakova, M.4
Zumba, O.5
Krausz, T.6
Jagadeeswaran, R.7
Salgia, R.8
-
9
-
-
0026448347
-
Met and hepatocyte growth factor/scatter factor signal transduction in normal melanocytes and melanoma cells
-
Halaban R, Rubin JS, Funasaka Y, Cobb M, Boulton T, Faletto D, Rosen E, Chan A, Yoko K, White W, et al. Met and hepatocyte growth factor/scatter factor signal transduction in normal melanocytes and melanoma cells. Oncogene 1992; 7: 2195-206.
-
(1992)
Oncogene
, vol.7
, pp. 2195-2206
-
-
Halaban, R.1
Rubin, J.S.2
Funasaka, Y.3
Cobb, M.4
Boulton, T.5
Faletto, D.6
Rosen, E.7
Chan, A.8
Yoko, K.9
White, W.10
-
10
-
-
0037633747
-
Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas
-
Cruz J, Reis-Filho JS, Silva P, Lopes JM,. Expression of c-met tyrosine kinase receptor is biologically and prognostically relevant for primary cutaneous malignant melanomas. Oncology 2003; 65: 72-82.
-
(2003)
Oncology
, vol.65
, pp. 72-82
-
-
Cruz, J.1
Reis-Filho, J.S.2
Silva, P.3
Lopes, J.M.4
-
11
-
-
0027997656
-
Detection of the c-met proto-oncogene product in normal skin and tumours of melanocytic origin
-
Saitoh K, Takahashi H, Sawada N, Parsons PG,. Detection of the c-met proto-oncogene product in normal skin and tumours of melanocytic origin. J Pathol 1994; 174: 191-9.
-
(1994)
J Pathol
, vol.174
, pp. 191-199
-
-
Saitoh, K.1
Takahashi, H.2
Sawada, N.3
Parsons, P.G.4
-
12
-
-
49649103221
-
The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis
-
Riker AI, Enkemann SA, Fodstad O, Liu S, Ren S, Morris C, Xi Y, Howell P, Metge B, Samant RS, Shevde LA, Li W, et al. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis. BMC Med Genomics 2008; 1: 13.
-
(2008)
BMC Med Genomics
, vol.1
, pp. 13
-
-
Riker, A.I.1
Enkemann, S.A.2
Fodstad, O.3
Liu, S.4
Ren, S.5
Morris, C.6
Xi, Y.7
Howell, P.8
Metge, B.9
Samant, R.S.10
Shevde, L.A.11
Li, W.12
-
13
-
-
0032533495
-
C-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype
-
Otsuka T, Takayama H, Sharp R, Celli G, LaRochelle WJ, Bottaro DP, Ellmore N, Vieira W, Owens JW, Anver M, Merlino G,. c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype. Cancer Res 1998; 58: 5157-67.
-
(1998)
Cancer Res
, vol.58
, pp. 5157-5167
-
-
Otsuka, T.1
Takayama, H.2
Sharp, R.3
Celli, G.4
Larochelle, W.J.5
Bottaro, D.P.6
Ellmore, N.7
Vieira, W.8
Owens, J.W.9
Anver, M.10
Merlino, G.11
-
14
-
-
14544268965
-
Detection of B-RAF and N-RAS mutations in human melanoma
-
Goydos JS, Mann B, Kim HJ, Gabriel EM, Alsina J, Germino FJ, Shih W, Gorski DH,. Detection of B-RAF and N-RAS mutations in human melanoma. J Am Coll Surg 2005; 200: 362-70.
-
(2005)
J Am Coll Surg
, vol.200
, pp. 362-370
-
-
Goydos, J.S.1
Mann, B.2
Kim, H.J.3
Gabriel, E.M.4
Alsina, J.5
Germino, F.J.6
Shih, W.7
Gorski, D.H.8
-
15
-
-
79952006295
-
Immunotherapy for melanoma
-
Weber J,. Immunotherapy for melanoma. Curr Opin Oncol 2011; 23: 163-9.
-
(2011)
Curr Opin Oncol
, vol.23
, pp. 163-169
-
-
Weber, J.1
-
16
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, Haanen JB, Ascierto P, Larkin J, Drummer R, Garbe C, Testori A, Maio M, Hogg D, Lorogan P, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011; 364: 2507-16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
Haanen, J.B.4
Ascierto, P.5
Larkin, J.6
Drummer, R.7
Garbe, C.8
Testori, A.9
Maio, M.10
Hogg, D.11
Lorogan, P.12
-
17
-
-
77957982878
-
Analysis of the genome to personalize therapy for melanoma
-
Davies MA, Samuels Y,. Analysis of the genome to personalize therapy for melanoma. Oncogene 2010; 29: 5545-55.
-
(2010)
Oncogene
, vol.29
, pp. 5545-5555
-
-
Davies, M.A.1
Samuels, Y.2
-
18
-
-
0028178840
-
RAS mutations in human melanoma: A marker of malignant progression
-
Ball NJ, Yohn JJ, Morelli JG, Norris DA, Golitz LE, Hoeffler JP,. RAS mutations in human melanoma: a marker of malignant progression. J Invest Dermatol 1994; 102: 285-90.
-
(1994)
J Invest Dermatol
, vol.102
, pp. 285-290
-
-
Ball, N.J.1
Yohn, J.J.2
Morelli, J.G.3
Norris, D.A.4
Golitz, L.E.5
Hoeffler, J.P.6
-
19
-
-
58149360787
-
NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma
-
Uffort DG, Grimm EA, Ellerhorst JA,. NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma. J Invest Dermatol 2009; 129: 148-54.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 148-154
-
-
Uffort, D.G.1
Grimm, E.A.2
Ellerhorst, J.A.3
-
20
-
-
58149181363
-
Cell line data base: Structure and recent improvements towards molecular authentication of human cell lines
-
Romano P, Manniello A, Aresu O, Armento M, Cesaro M, Parodi B,. Cell line data base: structure and recent improvements towards molecular authentication of human cell lines. Nucleic Acids Res 2009; 37: D925-32.
-
(2009)
Nucleic Acids Res
, vol.37
-
-
Romano, P.1
Manniello, A.2
Aresu, O.3
Armento, M.4
Cesaro, M.5
Parodi, B.6
-
21
-
-
79251474400
-
Clinical correlates of NRAS and BRAF mutations in primary human melanoma
-
Ellerhorst JA, Greene VR, Ekmekcioglu S, Warneke CL, Johnson MM, Cooke CP, Wang LE, Prieto VG, Gershenwald JE, Wei Q, Grimm EA,. Clinical correlates of NRAS and BRAF mutations in primary human melanoma. Clin Cancer Res 2011; 17: 229-35.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 229-235
-
-
Ellerhorst, J.A.1
Greene, V.R.2
Ekmekcioglu, S.3
Warneke, C.L.4
Johnson, M.M.5
Cooke, C.P.6
Wang, L.E.7
Prieto, V.G.8
Gershenwald, J.E.9
Wei, Q.10
Grimm, E.A.11
-
22
-
-
0037083273
-
Loss of MDA-7 expression with progression of melanoma
-
Ellerhorst JA, Prieto VG, Ekmekcioglu S, Broemeling L, Yekell S, Chada S, Grimm EA,. Loss of MDA-7 expression with progression of melanoma. J Clin Oncol 2002; 20: 1069-74.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1069-1074
-
-
Ellerhorst, J.A.1
Prieto, V.G.2
Ekmekcioglu, S.3
Broemeling, L.4
Yekell, S.5
Chada, S.6
Grimm, E.A.7
-
23
-
-
50249160548
-
Small molecule c-MET inhibitor PHA665752: Effect on cell growth and motility in papillary thyroid carcinoma
-
Chattopadhyay C, el-Naggar AK, Williams MD, Clayman GL,. Small molecule c-MET inhibitor PHA665752: effect on cell growth and motility in papillary thyroid carcinoma. Head Neck 2008; 30: 991-1000.
-
(2008)
Head Neck
, vol.30
, pp. 991-1000
-
-
Chattopadhyay, C.1
El-Naggar, A.K.2
Williams, M.D.3
Clayman, G.L.4
-
24
-
-
77956251704
-
Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells
-
Matsubara D, Ishikawa S, Oguni S, Aburatani H, Fukayama M, Niki T,. Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells. J Thorac Oncol 2010; 5: 1317-24.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1317-1324
-
-
Matsubara, D.1
Ishikawa, S.2
Oguni, S.3
Aburatani, H.4
Fukayama, M.5
Niki, T.6
-
25
-
-
32944467848
-
Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors
-
Burgess T, Coxon A, Meyer S, Sun J, Rex K, Tsuruda T, Chen Q, Ho SY, Li L, Kaufman S, McDorman K, Cattley RC, et al. Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors. Cancer Res 2006; 66: 1721-29.
-
(2006)
Cancer Res
, vol.66
, pp. 1721-1729
-
-
Burgess, T.1
Coxon, A.2
Meyer, S.3
Sun, J.4
Rex, K.5
Tsuruda, T.6
Chen, Q.7
Ho, S.Y.8
Li, L.9
Kaufman, S.10
McDorman, K.11
Cattley, R.C.12
-
26
-
-
49249100382
-
MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival
-
Jin H, Yang R, Zheng Z, Romero M, Ross J, Bou-Reslan H, Carano RA, Kasman I, Mai E, Young J, Zha J, Zhang Z, et al. MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival. Cancer Res 2008; 68: 4360-8.
-
(2008)
Cancer Res
, vol.68
, pp. 4360-4368
-
-
Jin, H.1
Yang, R.2
Zheng, Z.3
Romero, M.4
Ross, J.5
Bou-Reslan, H.6
Carano, R.A.7
Kasman, I.8
Mai, E.9
Young, J.10
Zha, J.11
Zhang, Z.12
-
27
-
-
0034636444
-
Dominant negative Met reduces tumorigenicity-metastasis and increases tubule formation in mammary cells
-
Firon M, Shaharabany M, Altstock RT, Horev J, Abramovici A, Resau JH, Vande Woude GF, Tsarfaty I,. Dominant negative Met reduces tumorigenicity- metastasis and increases tubule formation in mammary cells. Oncogene 2000; 19: 2386-97.
-
(2000)
Oncogene
, vol.19
, pp. 2386-2397
-
-
Firon, M.1
Shaharabany, M.2
Altstock, R.T.3
Horev, J.4
Abramovici, A.5
Resau, J.H.6
Vande Woude, G.F.7
Tsarfaty, I.8
-
28
-
-
7444231680
-
RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival
-
Shinomiya N, Gao CF, Xie Q, Gustafson M, Waters DJ, Zhang YW, Vande Woude GF,. RNA interference reveals that ligand-independent met activity is required for tumor cell signaling and survival. Cancer Res 2004; 64: 7962-70.
-
(2004)
Cancer Res
, vol.64
, pp. 7962-7970
-
-
Shinomiya, N.1
Gao, C.F.2
Xie, Q.3
Gustafson, M.4
Waters, D.J.5
Zhang, Y.W.6
Vande Woude, G.F.7
-
29
-
-
37549059613
-
Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma
-
Christensen JG, Zou HY, Arango ME, Li Q, Lee JH, McDonnell SR, Yamazaki S, Alton GR, Mroczkowski B, Los G,. Cytoreductive antitumor activity of PF-2341066, a novel inhibitor of anaplastic lymphoma kinase and c-Met, in experimental models of anaplastic large-cell lymphoma. Mol Cancer Ther 2007; 6: 3314-22.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 3314-3322
-
-
Christensen, J.G.1
Zou, H.Y.2
Arango, M.E.3
Li, Q.4
Lee, J.H.5
McDonnell, S.R.6
Yamazaki, S.7
Alton, G.R.8
Mroczkowski, B.9
Los, G.10
-
30
-
-
34249324494
-
An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms
-
Zou HY, Li Q, Lee JH, Arango ME, McDonnell SR, Yamazaki S, Koudriakova TB, Alton G, Cui JJ, Kung PP, Nambu MD, Los G, et al. An orally available small-molecule inhibitor of c-Met, PF-2341066, exhibits cytoreductive antitumor efficacy through antiproliferative and antiangiogenic mechanisms. Cancer Res 2007; 67: 4408-17.
-
(2007)
Cancer Res
, vol.67
, pp. 4408-4417
-
-
Zou, H.Y.1
Li, Q.2
Lee, J.H.3
Arango, M.E.4
McDonnell, S.R.5
Yamazaki, S.6
Koudriakova, T.B.7
Alton, G.8
Cui, J.J.9
Kung, P.P.10
Nambu, M.D.11
Los, G.12
-
31
-
-
73149091443
-
SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo
-
Buchanan SG, Hendle J, Lee PS, Smith CR, Bounaud PY, Jessen KA, Tang CM, Huser NH, Felce JD, Froning KJ, Peterman MC, Aubol BE, et al. SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Mol Cancer Ther 2009; 8: 3181-90.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3181-3190
-
-
Buchanan, S.G.1
Hendle, J.2
Lee, P.S.3
Smith, C.R.4
Bounaud, P.Y.5
Jessen, K.A.6
Tang, C.M.7
Huser, N.H.8
Felce, J.D.9
Froning, K.J.10
Peterman, M.C.11
Aubol, B.E.12
-
32
-
-
44449131293
-
ARQ197, a highly selective small molecule inhibitor of c-Met, with selective antitumor properties in a broad spectrum of human cancer cells
-
abstract
-
Jeay S, Munshi N, Hill J, Moussa M, Ashwell M, Leggett D, Li C,. ARQ197, a highly selective small molecule inhibitor of c-Met, with selective antitumor properties in a broad spectrum of human cancer cells. 2007 AACR Annual Meeting 2007 (abstract).
-
(2007)
AACR Annual Meeting 2007
-
-
Jeay, S.1
Munshi, N.2
Hill, J.3
Moussa, M.4
Ashwell, M.5
Leggett, D.6
Li, C.7
-
33
-
-
0027285320
-
Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target
-
Polakis P, McCormick F,. Structural requirements for the interaction of p21ras with GAP, exchange factors, and its biological effector target. J Biol Chem 1993; 268; 9157-60.
-
(1993)
J Biol Chem
, vol.268
, pp. 9157-9160
-
-
Polakis, P.1
McCormick, F.2
-
34
-
-
0032558793
-
Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis
-
Webb CP, Taylor GA, Jeffers M, Fiscella M, Oskarsson M, Resau JH, Vande Woude GF,. Evidence for a role of Met-HGF/SF during Ras-mediated tumorigenesis/metastasis. Oncogene 1998; 17: 2019-25.
-
(1998)
Oncogene
, vol.17
, pp. 2019-2025
-
-
Webb, C.P.1
Taylor, G.A.2
Jeffers, M.3
Fiscella, M.4
Oskarsson, M.5
Resau, J.H.6
Vande Woude, G.F.7
-
35
-
-
0038288765
-
Hepatocyte growth factor modulates motility and invasiveness of ovarian carcinomas via ras mediated pathway
-
Ueoka Y, Kato K, Wake N,. Hepatocyte growth factor modulates motility and invasiveness of ovarian carcinomas via ras mediated pathway. Mol Cell Endocrinol 2003; 202: 81-8.
-
(2003)
Mol Cell Endocrinol
, vol.202
, pp. 81-88
-
-
Ueoka, Y.1
Kato, K.2
Wake, N.3
|