Antileishmanial, antitrypanosomal, and cytotoxic screening of ethnopharmacologically selected Peruvian plants

Parasitology Research

Volumn 110, Issue 4, 2012, Pages 1381-1392

  González Coloma, Azucena ^a   Reina, Matías ^b   Sáenz, Claudia ^a   Lacret, Rodney ^c   Ruiz Mesia, Lastenia ^d   Arán, Vicente J ^e   Sanz, Jesús ^f   Martínez Díaz, Rafael A ^g  

^a INSTITUTO DE CIENCIAS AGRARIAS   (Spain)

^b INSTITUTO DE PRODUCTOS NATURALES Y AGROBIOLOGÍA   (Spain)

^c UNIVERSITY OF CÁDIZ   (Spain)

^d UNIVERSIDAD NACIONAL DE LA AMAZONÍA PERUANA   (Peru)

^e INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^f INSTITUTO DE QUÍMICA ORGÁNICA GENERAL   (Spain)

^g UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 NAPHTHOQUINONE 2 ACETYL 4H,9H NAPHTHO[2,3 B]FURAN 4,9 DIONE; 12 O METHYL CURINE; 2 (1 HYDROXETHYL) 4H,9H NAPHTHO[2,3 B]FURAN 4,9 DIONE; ALCOHOL; AMPHOTERICIN B; ANTILEISHMANIAL AGENT; ANTITRYPANOSOMAL AGENT; ARISTOLOQUIA PILOSA EXTRACT; BRUNFELSIA GRANDIFLORA EXTRACT; CEDRELA ODORATA EXTRACT; CHLOROFORM; CHONDODENDRON TOMENTOSUM EXTRACT; CHONDROCURINE; CYCLEANINE; HEXANE; METHYLAZOXYMETHANOL GLUCOSIDE; NIFURTIMOX; PAULLINIA CLAVIGERA EXTRACT; PLANT EXTRACT; TABEBUIA SERRATIFOLIA EXTRACT; TRADESCANTIA ZEBRINA EXTRACT; UNCLASSIFIED DRUG; WATER; ZAMIA ULEI EXTRACT;

ANTILEISHMANIAL ACTIVITY; ANTITRYPANOSOMAL ACTIVITY; ARISTOLOQUIA PILOSA; ARTICLE; BARK; BRUNFELSIA GRANDIFLORA; CARBON NUCLEAR MAGNETIC RESONANCE; CEDRELA ODORATA; CELL VIABILITY; CHONDODENDRON TOMENTOSUM; COLUMN CHROMATOGRAPHY; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; EPIMASTIGOTE; ETHNOPHARMACOLOGY; EXTRACTION; IN VITRO STUDY; LEISHMANIA INFANTUM; MASS FRAGMENTOGRAPHY; MEDICINAL PLANT; NONHUMAN; PARASITE VIABILITY; PAULLINIA CLAVIGERA; PERU; PHYTOCHEMISTRY; PLANT LEAF; PRIORITY JOURNAL; PROMASTIGOTE; PROTON NUCLEAR MAGNETIC RESONANCE; RURAL AREA; SPECTROSCOPY; TABEBUIA SERRATIFOLIA; TRADESCANTIA ZEBRINA; TRADITIONAL MEDICINE; TRYPANOSOMA CRUZI; ZAMIA ULEI;

ANIMALS; ANTIPROTOZOAL AGENTS; CHO CELLS; CRICETINAE; CYTOTOXINS; ETHNOPHARMACOLOGY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HEXANES; LEISHMANIA INFANTUM; MEDICINE, TRADITIONAL; PERU; PLANT BARK; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; TRYPANOSOMA CRUZI;

CEDRELA ODORATA; LEISHMANIA INFANTUM; MAMMALIA; TABEBUIA SERRATIFOLIA; TRADESCANTIA ZEBRINA; TRYPANOSOMA; TRYPANOSOMA CRUZI; ZAMIA;

EID: 84861567692     PISSN: 09320113     EISSN: 14321955     Source Type: Journal    
DOI: 10.1007/s00436-011-2638-3     Document Type: Article

References (49)

1. Angerhofer C, Guinaudeau H, Wongpanich V, Pezzuto JM, Cordell A (1999) Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids. J Nat Prod 62:59-66 (Pubitemid 29071377)
2. Cao S, Schilling JK, Miller JS, Andriantsiferana R, Rasamison VE, Kingston DG (2004) Cytotoxic compounds from Mundulea chapelieri from the Madagascar Rainforest. J Nat Prod 67:454-456 (Pubitemid 38405714)
3. Colman de Saizarbitoria T, Anderson JE, Alfonso D, MacLaughlin JL (1997) Bioactive furonaphtoquinones from Tabebuia barbata, Bignoniaceae. Acta Cient Venez 48:42-46 (Pubitemid 127472609)
4. Correa DS, Tempone AG, Reimao JQ, Taniwaki NN, Romoff P, Fávero OA, Sartorelli P, Mecchi MC, Lago JHG (2011) Antileishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis. Parasitol Res 109:231-236
5. Croft SL, Barrett MP, Urbina JA (2005) Chemotherapy of trypanosomiases and leishmaniasis. Trends Parasitol 21:508-512 (Pubitemid 41447021)
6. Do Campo R, Lopes JN, Cruz FS, De Soua W (1977) Trypanosoma cruzi: Ultrastructural and metabolic alterations of epimastigotes by β-lapachone. Exp Parasitol 42:142-149 (Pubitemid 8118199)
7. Do Campo R, Cruz FS, Boveris A, Muniz RP, Esquibel DM (1978) Lipid peroxidation and the generation of free radicals, superoxide anion, and hydrogen peroxide in beta-lapachone-treated Trypanosoma cruzi epimastigotes. Arch Biochem Biophys 186:292-297 (Pubitemid 8311794)
8. Everette AJ, Lowe LA, Wilkinson S (1970) Revision of the structure of (+)-tubocurarine chloride and (+)-chondrocurine. J Chem Soc D 1970:1020-1021
9. Estevez Y, Castillo D, Pisango MT, Arevalo J, Rojas R, Alban J, Deharo E, Bourdy G, Sauvain M (2007) Evaluation of the leishmanicidal activity of plants used by Peruvian Chayahuita ethnic group. J Ethnopharmacol 114:254-259 (Pubitemid 47554611)
10. Fournet A, Muñoz V (2002) Natural products as trypanocidal, antileishmanial and antimalarial drugs. Curr Top Med Chem 2:1215-1237
11. Fournet A, Ferreira ME, Rojas de Arias A, Schinini A, Nakayama H, Torres S, Sanabria R, Guinaudeau H, Bruneton J (1997) The effects of bisbenzylisoquinoline alkaloids in T. cruzi infections in mice. Int J Antimicrob Agents 8:163-170 (Pubitemid 27242773)
12. Fournet A, Inchaustti A, Yaluff G, Rojas de Arias A, Guinaudeau H, Bruneton J, Breidenbach MA, Karplus PA, Faerman CH (1998) Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductasa. J Enzyme Inhib 13:1-9 (Pubitemid 28154261)
13. Gascon J, Bern C, Pinazo MJ (2010) Chagas disease in Spain, the United States and other non-endemic countries. Acta Trop 115:22-27
14. González-Coloma A, Guadaño A, de Inés C, Martínez-Díaz R, Cortés D (2002) Selective action of acetogenin mitochondrial Complex I inhibitors. Z Naturforsch 57C:1028-1034 (Pubitemid 36137347)
15. Ghosh S, Debnath S, Hazra S, Hartung A, Thomale K, Schutheis M, Kapkova P, Schurigt U, Moll H, Holzgrabe U, Hazra B (2011) Valeriana wallichii root extracts and fractions with activity against Leishmania spp. Parasitol Res 108:861-871
16. Haynes LJ, Herbert EJ, Plimmer JR (1966) (+ +)-4?-O-Methylcurine from Cissampelos pareira. J Chem Soc C 1966:615-617
17. Hussain H, Krohn K, Uddin Ahmad V, Abbas Miana G, Robert Green I (2007) Lapachol: An overview. ARKIVOC 2:145-171
18. Karabay NU, Sukatar A, Ozdemir G, Horzum Z (2007) Antimicrobial activity of volatile components and various extracts of the red alga Jania rubens. Phytother Res 21:153-156
19. Kuete V, Eyong KO, Folefoc GN, Beng VP, Hussain H, Krohn K, Nkengfack AE (2007) Antimicrobial activity of the methanolic extract and the chemical constituents isolated from Newbouilda laevis. Die Pharmazie 62:552-556 (Pubitemid 47083631)
20. Kuiate JR, Bessiere JM, Zollo PHA, Kuate SP (2006) Chemical composition and antidermatophytic properties of volatile fractions of hexanic extract from leaves of Cupressus lusitanica Mill. from Cameroon. J Ethnopharmacol 103:160-165 (Pubitemid 41796912)
21. Kvist LP, Christensen SB, Rasmussen HB, Mejía K, González A (2006) Identification and evaluation of Peruvian plants used to treat malaria and leishmaniasis. J Ethnopharmacol 106:390-402
22. Leboeuf M, Cavé A, Bhaunik PK, Mukherjee B, Mukherjee R (1982) The phytochemistry of the Annonaceae. Phytochemistry 21:2783-2813
23. Lin LZ, Shied HL, Angerhofer CK, Pezzuto JM, Cordell GA (1993) Citotoxic and antimalarial bisbenzylisoquinoline alkaloids from Cyclea barbata. J Nat Prod 56:22-29 (Pubitemid 23066674)
24. Lohombo-Ekomba ML, Okusa PN, Penge O, Kabongo C, Iqbal M, Kasende OE (2004) Antibacterial, antifungal, antiplasmodial and cytotoxic activities of Albertisia villosa. J Ethnopharmacol 93:331-335 (Pubitemid 38962425)
25. Mackinnon S, Durst T, Arnason JT (1997) Antimalarial activity of tropical Meliaceae extracts and gedunin derivatives. J Nat Prod 60:336-341 (Pubitemid 27184907)
26. Mazutti M, Mossi AJ, Cansian RL, Corazza ML, Dariva C, Oliveira V (2008) Chemical profile and antimicrobial activity of Boldo (Peumus boldus Molina). Extracts obtained by compressed carbon dioxide extraction. Braz J Chem Eng 25:427-434
27. Mejia K, Rengifo E (2000) Plantas medicinales de uso popular en la Amazonía Peruana. Instituto de Investigación de la Amazonía Peruana-Gobierno Regional de Loreto-Agencia Española de Cooperación Internacional, Lima
28. Mossman T (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
29. Muelas Serrano S, Nogal JJ, Martínez Díaz RA, Escario JA, Martínez Fernández AR, Gómez Barrio A (2000) In vitro screening of American plant extracts on Trypanosoma cruzi and Trichomonas vaginalis. J Ethnopharmacol 71:101-107 (Pubitemid 30440658)
30. Muñoz J, Portús M, Corachan M, Fumadó V, Gascona J (2007) Congenital Trypanosoma cruzi infection in a non-endemic area. Trans R Soc Trop Med Hyg 101:1161-1162 (Pubitemid 47454411)
31. Murray HW, Berman JD, Davies CR, Saravia NG (2005) Advances in leishmaniasis. Lancet 366:1561-1577 (Pubitemid 41540115)
32. Nishida K, Kobayashi A, Nagahama T (1955) Studies on cycasin, a new toxic glycoside of Cycas revoluta Thunb. Part I. Isolation and structure of cycasin. Bull Agric Chem Soc Japan 19:77-83
33. Nishida K, Kobayashi A, Nagahama T (1956) Studies on cycasin, a new toxic glycoside of Cycas revoluta Thunb. Part III. Isolatión of cycasin from the stem of Japanese cycad. Seikagaku 28:70-74
34. Osorio J, Montoya G, Arango G (2006) Productos naturales alcaloidales con actividad antiprotozoaria. Vitae 13:61-84
35. Passero LFD, Bonfim-Melo A, Corbett CEP, Laurenti MD, Toyama MH, de Toyama DO, Romoff P, Fávero OA, dos Grecco SS, Zalewsky CA, Lago JHG (2011) Anti-leishmanial effects of purified compounds from aerial parts of Baccharis uncinella C. (Asteraceae). Parasitol Res 108:529-536
36. Perez D, Iannacone J (2006) Effectiveness of botanical extracts from ten plants on mortality and larval repellency of Rhynchophorus palmarum L., an insect pest of the Peach palm Bactris gasipaes Kunth in Amazonian Peru. Agric Tec 66:21-30
37. Rao MM, Kingston DGI (1982) Plant anticancer agents. XII. Isolation and structure elucidation of new cytotoxic quinones from Tabebuia cassinoides. J Nat Prod 45:600-604 (Pubitemid 13142614)
38. Reina M, González-Coloma A, Gutiérrez C, Cabrera R, Rodríguez ML, Villarroel L, Fajardo V (2001) Defensive chemistry of Senecio miser Hook. J Nat Prod 64:6-11 (Pubitemid 32109266)
39. Rojas R, Bustamante B, Bauer J, Fernández I, Albán J, Lock O (2003) Antimicrobial activity of selected Peruvian medicinal plants. J Ethnopharmacol 88:199-204 (Pubitemid 37083447)
40. Sánchez-Cañete MP, Carvalho L, Pérez-Victoria FJ, Gamarro F, Castanys S (2009) Low plasma membrane expression of the miltefosine transport complex renders Leishmania braziliensis refractory to the drug. Antimicrob Agents Chemother 53:1305-1313
41. Schneider D, Wink M, Sporer F (2002) Cycads: Their evolution, toxins, herbivores and insect pollinators. Naturwissenschaften 89:281-294 (Pubitemid 34827943)
42. Scheinmann F, Scriven EFV, Ogbeibe ON (1980) Cycleanine from Synclisia scabrida: Conformational information from the 1H NMR spectrum at 300 MHz. Phytochemistry 19:1837-1840
43. Sra KK, Sracic J, Tyring SK (2004) Treatment of protozoan infections. Dermatol Ther 17:513-516 (Pubitemid 39657280)
44. Thornber CW (1970) Alkaloids of the Menispermaceae. Phytochemistry 9:157-187
45. Tshibangu JN, Wright AD, Köning GM (2003) HPLC isolation of the antiplasmodially active bisbenzylisoquinoline alkaloids present in roots of Cissampelos mucronata. Phytochem Anal 14:13-22 (Pubitemid 36193286)
46. Weiss CR, Moideen SVK, Croft SL, Houghton PJ (2000) Activity of extracts and isolated naphthoquinones from Kigelia pinnata against Plasmodium falciparum. J Nat Prod 63:1306-1309
47. Yagi F (2004) Azoxyglycoside content and β-glycosidase activities in leaves of various cycads. Phytochemistry 65:3243-3247 (Pubitemid 39550391)
48. Zai-Chang Y, Bo-Chu W, Xio-Sheng Y, Qiang W (2005) Chemical composition of the volatile oil from Cynanchum stauntonii and its activities of anti-influenza virus. Colloid Surf B Biointerfaces 43:198-202 (Pubitemid 40909842)
49. Zani CL, De Oliveira AB, De Oliveira GG (1991) Furonaphthoquinones from Tabebuia ochracea. Phytochemistry 30:2379-2381