A possible connection between adhesion regulating molecule 1 overexpression and nuclear factor kappa B activity in hepatocarcinogenesis

Oncology Reports

Volumn 28, Issue 1, 2012, Pages 283-290

  Yang, Xin ^a   Miao, Xiongying ^a   Wen, Yu ^a   Hu, Jixiong ^a   Dai, Weidong ^a   Yin, Bangliang ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Adhesion regulating molecule 1; Hepatocellular carcinoma; Nuclear factor kappa B; Overexpression; Short hairpin RNA

Indexed keywords

ADHESION REGULATING MOLECULE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADULT; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; LIVER NEOPLASMS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NEOPLASM INVASIVENESS; NF-KAPPA B; RNA INTERFERENCE; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84861564461     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1767     Document Type: Article

References (27)

1. Yao T, Song L, Xu W, DeMartino GN, Florens L, Swanson SK, Washburn MP, Conaway RC, Conaway JW and Cohen RE: Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1. Nat Cell Biol 8: 994-1002, 2006. (Pubitemid 44314731)
2. Jørgensen JP, Lauridsen AM, Kristensen P, Dissing K, Johnsen AH, Hendil KB and Hartmann-Petersen R: Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor. J Mol Biol 360: 1043-1052, 2006. (Pubitemid 44062521)
3. Hamazaki J, Iemura S, Natsume T, Yashiroda H, Tanaka K and Murata S: A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes. EMBO J 25: 4524-4536, 2006. (Pubitemid 44498126)
4. Qiu XB, Ouyang SY, Li CJ, Miao S, Wang L and Goldberg AL: hRpn13/ADRM1/GP110 is a novel proteasome subunit that binds the deubiquitinating enzyme, UCH37. EMBO J 25: 5742-5753, 2006. (Pubitemid 44967758)
5. Husnjak K, Elsasser S, Zhang N, Chen X, Randles L, Shi Y, Hofmann K, Walters KJ, Finley D and Dikic I: Proteasome subunit Rpn13 is a novel ubiquitin receptor. Nature 453: 481-488, 2008. (Pubitemid 351733317)
6. Simins AB, Weighardt H, Weidner KM, Weidle UH and Holzmann B: Functional cloning of ARM-1, an adhesion-regulating molecule upregulated in metastatic tumor cells. Clin Exp Metastasis 17: 641-648, 1999. (Pubitemid 30450185)
7. Lamerant N and Kieda C: Adhesion properties of adhesionregulating molecule 1 protein on endothelial cells. FEBS J 272: 1833-1844, 2005. (Pubitemid 40547242)
8. Kim T, Ha HI, Kim N, Yi O, Lee SH and Choi Y: Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation. Biochem Biophys Res Commun 390: 585-590, 2009.
9. Al-Shami A, Jhaver KG, Vogel P, Wilkins C, Humphries J, Davis JJ, Xu N, Potter DG, Gerhardt B, Mullinax R, Shirley CR, Anderson SJ and Oravecz T: Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development. PLoS One 5: e13654, 2010.
10. Pilarsky C, Wenzig M, Specht T, Saeger HD and Grützmann R: Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia 6: 744-750, 2004. (Pubitemid 40041492)
11. Carvalho B, Postma C, Mongera S, Hopmans E, Diskin S, van de Wiel MA, van Criekinge W, Thas O, Matthäi A, Cuesta MA, Terhaar Sive Droste JS, Craanen M, Schröck E, Ylstra B and Meijer GA: Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression. Gut 58: 79-89, 2009.
12. Fejzo MS, Dering J, Ginther C, Anderson L, Ramos L, Walsh C, Karlan B and Slamon DJ: Comprehensive analysis of 20q13 genes in ovarian cancer identifies ADRM1 as amplification target. Genes Chromosomes Cancer 47: 873-883, 2008.
13. Sen R and Baltimore D: Inducibility of kappa immunoglobulin enhancer-binding protein NF-kappa B by a posttranslational mechanism. Cell 47: 921-928, 1986. (Pubitemid 17005065)
14. Karin M, Lawrence T and Nizet V: Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 124: 823-835, 2006. (Pubitemid 43261455)
15. Pacifico F and Leonardi A: NF-kappaB in solid tumors. Biochem Pharmacol 72: 1142-1152, 2006.
16. Liu P, Kimmoun E, Legrand A, Sauvanet A, Degott C, Lardeux B and Bernuau D: Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas. J Hepatol 37: 63-71, 2002. (Pubitemid 34713056)
17. Tai DI, Tsai SL, Chang YH, Huang SN, Chen TC, Chang KS and Liaw YF: Constitutive activation of nuclear factor kappaB in hepatocellular carcinoma. Cancer 89: 2274-2281, 2000.
18. Chan CF, Yau TO, Jin DY, Wong CM, Fan ST and Ng IO: Evaluation of nuclear factor-kappaB, urokinase-type plasminogen activator, and HBx and their clinicopathological significance in hepatocellular carcinoma. Clin Cancer Res 10: 4140-4149, 2004.
19. Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E and Ben-Neriah Y: NF-kappaB functions as a tumor promoter in inflammation-associated cancer. Nature 431: 461-466, 2006. (Pubitemid 39329586)
20. Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A and Heikenwalder M: A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell 16: 295-308, 2009.
21. Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001. (Pubitemid 34164012)
22. Schmittgen TD and Livak KJ: Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3: 1101-1108, 2008. (Pubitemid 351818697)
23. Chen Q, Gong B, Mahmoud-Ahmed AS, Zhou A, Hsi ED, Hussein M and Almasan A: Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma. Blood 98: 2183-2192, 2001.
24. Li Y, Tang ZY, Ye SL, Liu YK, Chen J, Xue Q, Chen J, Gao DM and Bao WH: Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97. World J Gastroenterol 7: 630-636, 2001. (Pubitemid 32994410)
25. Chen W, Hu XT, Shi QL, Zhang FB and He C: Knockdown of the novel proteasome subunit Adrm1 located on the 20q13 amplicon inhibits colorectal cancer cell migration, survival and tumorigenicity. Oncol Rep 21: 531-537, 2009.
26. Wang P, Mariman E, Keijer J, Bouwman F, Noben JP, Robben J and Renes J: Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines. Cell Mol Life Sci 61: 2405-2417, 2004. (Pubitemid 39382030)
27. Mazumdar T, Gorgun FM, Sha Y, Tyryshkin A, Zeng S, Hartmann-Petersen R, Jørgensen JP, Hendil KB and Eissa NT: Regulation of NF-kappaB activity and inducible nitric oxide synthase by regulatory particle non-ATPase subunit 13 (Rpn13). Proc Natl Acad Sci USA 107: 13854-13859, 2010.