Neuroprotective effects of minocycline on double-stranded RNA-induced neurotoxicity in cultured cortical neurons

Hong Kong Medical Journal

Volumn 18, Issue SUPP2, 2012, Pages 42-44

  Yik, S Y ^a   Yu, M S ^a   Ho, Y S ^a   Lai, C S W ^a   Cheung, Y T ^a   So, K F ^a   Chang, R C C ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DOUBLE STRANDED RNA; GLYCOCONJUGATE; MEMANTINE; MINOCYCLINE; RNA DERIVATIVE; AMINO ACID RECEPTOR BLOCKING AGENT; ANTIINFECTIVE AGENT; LACTATE DEHYDROGENASE; NEUROPROTECTIVE AGENT;

ARTICLE; BRAIN CELL; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LYCIUM; NEUROPROTECTION; NEUROTOXICITY; TREATMENT RESPONSE; ANALYSIS OF VARIANCE; APOPTOSIS; DRUG EFFECT; ENZYMOLOGY; JAPANESE ENCEPHALITIS; METABOLISM; NERVE CELL; PATHOLOGY; TOXICITY AND INTOXICATION; TUMOR CELL LINE;

ANALYSIS OF VARIANCE; ANTI-BACTERIAL AGENTS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; ENCEPHALITIS, JAPANESE; EXCITATORY AMINO ACID ANTAGONISTS; GLYCOCONJUGATES; HUMANS; L-LACTATE DEHYDROGENASE; MEMANTINE; MINOCYCLINE; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; RNA, DOUBLE-STRANDED;

EID: 84861563075     PISSN: 10242708     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Tikka TM, Koistinaho JE. Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia. J Immunol 2001;166:7527-33.
2. Tikka TM, Vartiainen NE, Goldsteins G, et al. Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease. Brain 2002;125:722-31.
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6. Lai CS, Yu MS, Yuen WH, So KF, Zee SY, Chang RC. Antagonizing beta-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum. Brain Res 2008;1190:215-24.