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Volumn 28, Issue 1, 2012, Pages 319-323

L-carnitine and cancer cachexia. I. L-carnitine distribution and metabolic disorders in cancer cachexia

Author keywords

Cancer cachexia; Fatty acid; L carnitine; Lipid emulsion

Indexed keywords

CARNITINE; LIPID; LONG CHAIN TRIACYLGLYCEROL; MEDIUM CHAIN TRIACYLGLYCEROL;

EID: 84861558882     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1804     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 0031305060 scopus 로고    scopus 로고
    • Biological variation of free and total carnitine in serum of healthy subjects
    • Alberty R and Albertyova D: Biological variation of free and total carnitine in serum of healthy subjects. Clin Chem 43: 2441-2443, 1997.
    • (1997) Clin Chem , vol.43 , pp. 2441-2443
    • Alberty, R.1    Albertyova, D.2
  • 2
    • 33846386102 scopus 로고    scopus 로고
    • Total carnitine and acylated carnitine ratio: Relationship of free carnitine with lipid parameters in pediatric dialysis patients
    • Marin VB, Azocar M, Molina M, Guerrero JL, Ratner R and Cano F: Total carnitine and acylated carnitine ratio: relationship of free carnitine with lipid parameters in pediatric dialysis patients. Adv Perit Dial 22: 130-135, 2006.
    • (2006) Adv Perit Dial , vol.22 , pp. 130-135
    • Marin, V.B.1    Azocar, M.2    Molina, M.3    Guerrero, J.L.4    Ratner, R.5    Cano, F.6
  • 3
    • 77954248039 scopus 로고    scopus 로고
    • Altered metabolism in cancer
    • Locasale JW and Cantley LC: Altered metabolism in cancer. BMC Biol 8: 88, 2010.
    • (2010) BMC Biol , vol.8 , pp. 88
    • Locasale, J.W.1    Cantley, L.C.2
  • 4
    • 52649107626 scopus 로고    scopus 로고
    • Cancer cell metabolism: Warburg and beyond
    • Hsu PP and Sabatini DM: Cancer cell metabolism: Warburg and beyond. Cell 134: 703-707, 2008.
    • (2008) Cell , vol.134 , pp. 703-707
    • Hsu, P.P.1    Sabatini, D.M.2
  • 5
    • 18044361914 scopus 로고    scopus 로고
    • Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care - Correlations with food intake, metabolism, exercise capacity, and hormones
    • DOI 10.1002/cncr.21013
    • Fouladiun M, Körner U, Bosaeus I, Daneryd P, Hyltander A and Lundholm KG: Body composition and time course changes in regional distribution of fat and lean tissue in unselected cancer patients on palliative care - correlations with food intake, metabolism, exercise capacity, and hormones. Cancer 103: 2189-2198, 2005. (Pubitemid 40605128)
    • (2005) Cancer , vol.103 , Issue.10 , pp. 2189-2198
    • Fouladiun, M.1    Korner, U.2    Bosaeus, I.3    Daneryd, P.4    Hyltander, A.5    Lundholm, K.G.6
  • 6
    • 79955399340 scopus 로고    scopus 로고
    • Definition and classifi- cation of cancer cachexia: An international consensus
    • Fearon K, Strasser F, Anker SD, et al: Definition and classifi- cation of cancer cachexia: an international consensus. Lancet Oncol 12: 489-495, 2011.
    • (2011) Lancet Oncol , vol.12 , pp. 489-495
    • Fearon, K.1    Strasser, F.2    Anker, S.D.3
  • 8
    • 0036896836 scopus 로고    scopus 로고
    • Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle
    • DOI 10.1172/JCI200215715
    • Rasmussen BB, Holmback UC, Volpi E, Morio-Liondore B, Paddon-Jones D and Wolfe RR: Malonyl coenzyme A and the regulation of functional carnitine palmitoyltransferase-1 activity and fat oxidation in human skeletal muscle. J Clin Invest 110: 1687-1693, 2002. (Pubitemid 35424247)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.11 , pp. 1687-1693
    • Rasmussen, B.B.1    Holmback, U.C.2    Volpi, E.3    Morio-Liondore, B.4    Paddon-Jones, D.5    Wolfe, R.R.6
  • 9
    • 33845335159 scopus 로고    scopus 로고
    • Molecular system bioenergetics: Regulation of substrate supply in response to heart energy demands
    • DOI 10.1113/jphysiol.2006.120584
    • Saks V, Favier R, Guzun R, Schlattner U and Wallimann T: Molecular system bioenergetics: regulation of substrate supply in response to heart energy demands. J Physiol 577: 769-777, 2006. (Pubitemid 44873644)
    • (2006) Journal of Physiology , vol.577 , Issue.3 , pp. 769-777
    • Saks, V.A.1    Favier, R.2    Guzun, R.3    Schlattner, U.4    Wallimann, T.5
  • 10
    • 0033978634 scopus 로고    scopus 로고
    • Cancer and anticancer therapy-induced modifications on metabolism mediated by carnitine system
    • DOI 10.1002/(SICI)1097-4652(200003)182:3<339::AID-JCP4>3.0.CO;2-B
    • Peluso G, Nicolai R, Reda E, Benatti P, Barbarisi A and Calvani M: Cancer and anticancer therapy-induced modifications on metabolism mediated by carnitine system. J Cell Physiol 182: 339-350, 2000. (Pubitemid 30054367)
    • (2000) Journal of Cellular Physiology , vol.182 , Issue.3 , pp. 339-350
    • Peluso, G.1    Nicolai, R.2    Reda, E.3    Benatti, P.4    Barbarisi, A.5    Calvani, M.6
  • 11
    • 34247385833 scopus 로고    scopus 로고
    • Urinary excretion of l-carnitine and its short-chain acetyl-l-carnitine in patients undergoing carboplatin treatment
    • DOI 10.1007/s00280-006-0341-3
    • Mancinelli A, D'Iddio S, Bisonni R, Graziano F, Lippe P and Calvani M: Urinary excretion of L-carnitine and its short-chain acetyl-L-carnitine in patients undergoing carboplatin treatment. Cancer Chemother Pharmacol 60: 19-26, 2007. (Pubitemid 46643713)
    • (2007) Cancer Chemotherapy and Pharmacology , vol.60 , Issue.1 , pp. 19-26
    • Mancinelli, A.1    D'Iddio, S.2    Bisonni, R.3    Graziano, F.4    Lippe, P.5    Calvani, M.6
  • 12
    • 3042743712 scopus 로고    scopus 로고
    • Role of nutritional intervention in patients treated with radiotherapy for pelvic malignancy
    • McGough C, Baldwin C, Frost G and Andreyev HJ: Role of nutritional intervention in patients treated with radiotherapy for pelvic malignancy. Br J Cancer 90: 2278-2287, 2004. (Pubitemid 38961889)
    • (2004) British Journal of Cancer , vol.90 , Issue.12 , pp. 2278-2287
    • McGough, C.1    Baldwin, C.2    Frost, G.3    Andreyev, H.J.N.4
  • 13
    • 0021963816 scopus 로고
    • Critical evaluation of the role of nutritional support for radiation therapy patients
    • Pezner R and Archambeau JO: Critical evaluation of the role of nutritional support for radiation therapy patients. Cancer 55: 263-267, 1985. (Pubitemid 15155452)
    • (1985) Cancer , vol.55 , Issue.1 SUPPL. , pp. 263-267
    • Pezner, R.1    Archambeau, J.O.2
  • 14
    • 0022885154 scopus 로고
    • Spectrophotometry of carnitine in biological fluids and tissue with Cobas Bio centrifugal analyzer
    • Cederblad G, Harper P and Lindgren K: Spectrophotometry of carnitine in biological fluids and tissue with a Cobas Bio centrifugal analyzer. Clin Chem 32: 342-346, 1986. (Pubitemid 17025655)
    • (1986) Clinical Chemistry , vol.32 , Issue.2 , pp. 342-346
    • Cederblad, G.1    Harper, P.2    Lindgren, K.3
  • 17
    • 0019310364 scopus 로고
    • Tissue distribution of carnitine biosynthetic enzymes in man
    • Rebouche CJ and Engel AG: Tissue distribution of carnitine biosynthetic enzymes in man. Biochim Biophys Acta 630: 22-29, 1980. (Pubitemid 10019432)
    • (1980) Biochimica et Biophysica Acta , vol.630 , Issue.1 , pp. 22-29
    • Rebouche, C.J.1    Engel, A.G.2
  • 18
    • 0020410190 scopus 로고
    • Sites and regulation of carnitine biosynthesis in mammals
    • Rebouche CJ: Sites and regulation of carnitine biosynthesis in mammals. Fed Proc 41: 2848-2852, 1982.
    • (1982) Fed Proc , vol.41 , pp. 2848-2852
    • Rebouche, C.J.1
  • 20
    • 0019161270 scopus 로고
    • The twenty-four-hour urinary excretion of carnitine and creatinine in normal and hypothyroid children
    • DOI 10.1016/0006-2944(80)90002-2
    • Eanes RZ and Biniek RL: The twenty-four-hour urinary excretion of carnitine and creatinine in normal and hypothyroid children. Biochem Med 24: 110-117, 1980. (Pubitemid 11238896)
    • (1980) Biochemical Medicine , vol.24 , Issue.2 , pp. 110-117
    • Eanes, R.Z.1    Biniek, R.L.2
  • 21
    • 0012738864 scopus 로고    scopus 로고
    • Pharmacokinetics of L-carnitine
    • DOI 10.2165/00003088-200342110-00002
    • Evans AM and Fornasini G: Pharmacokinetics of L-carnitine. Clin Pharmacokinet 42: 941-967, 2003. (Pubitemid 37056103)
    • (2003) Clinical Pharmacokinetics , vol.42 , Issue.11 , pp. 941-967
    • Evans, A.M.1    Fornasini, G.2
  • 25
    • 0025887050 scopus 로고
    • Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells
    • Matthys P, Dijkmans R, Proost P, et al: Severe cachexia in mice inoculated with interferon-gamma-producing tumor cells. Int J Cancer 49: 77-82, 1991.
    • (1991) Int J Cancer , vol.49 , pp. 77-82
    • Matthys, P.1    Dijkmans, R.2    Proost, P.3
  • 26
    • 0032947267 scopus 로고    scopus 로고
    • Muscle protein breakdown and the critical role of the ubiquitinproteasome pathway in normal and disease states
    • Lecker SH, Solomon V, Mitch WE and Goldberg AL: Muscle protein breakdown and the critical role of the ubiquitinproteasome pathway in normal and disease states. J Nutr 129: S227-S237, 1999.
    • (1999) J Nutr , vol.129
    • Lecker, S.H.1    Solomon, V.2    Mitch, W.E.3    Goldberg, A.L.4
  • 27
    • 34147166505 scopus 로고    scopus 로고
    • Skeletal muscle atrophy, a link between depression of protein synthesis and increase in degradation
    • DOI 10.1074/jbc.M610378200
    • Eley HL and Tisdale MJ: Skeletal muscle atrophy, a link between depression of protein synthesis and increase in degradation. J Biol Chem 282: 7087-7097, 2007. (Pubitemid 47093637)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.10 , pp. 7087-7097
    • Eley, H.L.1    Tisdale, M.J.2
  • 28
    • 67649982995 scopus 로고    scopus 로고
    • Mechanisms of cancer cachexia
    • Tisdale MJ: Mechanisms of cancer cachexia. Physiol Rev 89: 381-410, 2009.
    • (2009) Physiol Rev , vol.89 , pp. 381-410
    • Tisdale, M.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.