Lp (a), uric acid, oxidants and antioxidant vitamins in type 2 diabetic patients without cardiovascular complications

Journal of Clinical and Diagnostic Research

Volumn 5, Issue 6, 2012, Pages 1161-1164

  Suchitra, M M ^a   Pallavi, M ^a   Shivaprasad, P ^a   Sachan, A ^a   Madhusudhana, Rao A ^a   Bitla, Aparna R ^a   Srinivasa, Rao P V L N ^a  

^a SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Antioxidants; CVD risk factors; Lp (a); Oxidative stress; Serum uric acid; Type 2 diabetes mellitus

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BIOLOGICAL MARKER; CHOLESTEROL; GLUCOSE; LIPID PEROXIDE; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; URIC ACID; VITAMIN;

ADULT; AGED; ARTICLE; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE DURATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; LIPID ANALYSIS; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; RISK ASSESSMENT; TRIACYLGLYCEROL BLOOD LEVEL; URIC ACID BLOOD LEVEL; VITAMIN BLOOD LEVEL;

EID: 84861557099     PISSN: 2249782X     EISSN: 0973709X     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. International Diabetes Federation (IDF). Diabetes Atlas, 3rd ed., 2007.
2. Centers for Disease Control and Prevention. National Diabetes Fact Sheet, 2005. Atlanta, Ga: Centers for Disease Control and Prevention, U.S. Dept of Health and Human Services, 2005. http://www.cdc.gov./diabetes/pubs/pdf/ndfs_2005.pdf. Updated December 20,2005. Accessed October, 10, 2007.
3. Ceriello A. Oxidative stress and diabetes-associated complications. Endocr Pract. 2006; 12:60-2.
4. Bonnefont-Rousselot D, Bastard JP, Jaudon MC, Delattre J. Conse quences of the diabetic status on the oxidant/antioxidant balance. Diabetes Metab 2000; 26:163-76.
5. Suryawanshi NP, Bhutey AK, Nagdeote AN, Jadhav AA, Manoorkar GS. Study of lipid peroxide and the lipid profile in diabetes mellitus. Indian J of Clin Biochem 2006; 21: 126-30.
6. Pasupathi P, Saravanan G, Chinnaswamy P, Bakthavathsalam G. Evaluation of oxidative stress and the antioxidant status in patients with diabetes mellitus. J. App. Sci. Res 2009; 5: 770-5.
7. Deepa R, Mohan A, Rema M, Haranath SP, Saravanan G, Mohan V, et al. Lp (a) in south Indian type 2 diabetes mellitus subjects with respect to the diabetic vascular complications. J Assoc Physicians India 2002; 50: 57-61.
8. Mohan V, Deepa R, Haranath SP, Premalatha G, Rema M, Sastry NG et al. Lipoprotein (a) is an independent risk factor for coronary artery disease in NIDDM patients in south India. Diabetes Care 1998; 21:1819-23.
9. Butler R, Morris AD, Belch JJ, Hill A, Struthers AD. Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension 2000; 35: 746-51.
10. Baker H, Frank O, De Angelis B, Feingold S. Plasma tocopherol in man at various periods after ingesting free or acetylated tocopherol. Nutr. Rep. Int 1980; 21: 531-6.
11. Roe HJ, Kuether CA. Detection of ascorbic acid in whole blood and urine through the 2, 4-dinitrophenyl-hydrazine derivative of dehydro ascorbic acid. J Biol Chem 1943; 147: 399-407.
12. Okawaha H, Ohishi N and Yagi K. Assay for lipid peroxides in animal tissue by using the thiobarbituric acid reaction. Annal Biochem 1979; 95: 351-8.
13. Merzouk S, Hichami A, Madani S, Merzouk H, Berrouiguet AY, Prost J, et al. Antioxidant status and levels of different vitamins as determined by high perfomance liquid chromatography in diabetic subjects with multiple complications. Gen. Physiol. Biophys. 2003; 22: 15-27.
14. Goldberg J. Clinical review 124: Diabetic dyslipidemia: causes and consequences. J Clin Endocrinal Metab 2001; 86:965-71.
15. Solfrizzi V, Panza F, Colacicco AM, Capurso C, D'Intorno A, Torees et al. Correlation of Lipoprotein (a) as a coronary risk factor with type 2 diabetes mellitus and low density lipoprotein cholesterol in patients who are >or =65 years of age. Am J cardiol 2002; 89: 825-9.
16. Singla S, Kaur K, Kaur G, Kaur H, Kaur J, Jaswal S, et al. Lipoprotein (a) in type II diabetes mellitus: correlation with HDL: LDL ratio and glycemic control. Int J Diab Dev Ctries 2009; 29: 80-4.
17. Heller FR, Jamart J, Honore P, Derue G, Novik V, Galanti L, et.al. Serum lipoprotein (a) in patients with type 2 diabetes mellitus. Diabetes Care 1993; 16:819-23.
18. Wolffenbuttel BH, Leurs PB, Sels JP, Rondas-Collbers GJ, Menheere PP, Nieuwenhuijzen Kruseman AC,et al. Improved blood glucose control by insulin therapy in type 2 diabetic patients has no effect on the lipoprotein (a) levels. Diabetic Med 1993; 10: 427-30.
19. Albahrani A, Alkindi M, Marks E, Alyahyaee S, Shenkin A. Lipoprotein (a): an independent risk factor for ischemic heart disease that was dependent on triglycerides in subjects with type 2 diabetes mellitus. Lipids Health Dis 2007; 6:26.
20. Patterson RA, Horsley ET, Leake DS. The prooxidant and antioxidant properties of human serum ultra filtrates toward LDL: important role of uric acid. J Lipid Res 2003; 44:512-21.
21. Nieto FJ, Iribarren C, Gross MD, Comstock GW, Cutler RG. Uric acid and serum antioxidant capacity: A reaction to atherosclerosis. Atherosclerosis 2000; 148:131-9.
22. Feig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N. Engl. J. Med. 2008; 359: 1811-21.
23. Corry DB, Eslami P, Yamamoto K, Nyby MD, Makino H, Tuck ML, et al. Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin-angiotensin system. J. Hypertens. 2008; 26:269-75.
24. Hayden MR, Tyagi SC. Uric acid: a new look at an old risk marker for cardiovascular disease, metabolic syndrome, and type 2 diabetes mellitus: the urate redox shuttle. Nutr Metab 2004; 1:10.