Noninvasive prenatal diagnosis of fetal trisomy 21 by allelic ratio analysis using targeted massively parallel sequencing of maternal plasma DNA

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Liao, Gary J W ^a   Chan, K C Allen ^a   Jiang, Peiyong ^a   Sun, Hao ^a   Leung, Tak Y ^a   Chiu, Rossa W K ^a   Dennis Lo, Y M ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENOMIC DNA;

ALLELE; ARTICLE; CHROMOSOME 13; CHROMOSOME 18; CHROMOSOME 21; CHROMOSOME 7; CLINICAL ARTICLE; COMPUTER SIMULATION; CONTROLLED STUDY; DNA EXTRACTION; DNA HYBRIDIZATION; DNA LIBRARY; DNA MICROARRAY; DNA SEQUENCE; FEASIBILITY STUDY; FEMALE; FETUS; GENE LOCUS; GENOTYPE; HUMAN; HUMAN CELL; NON INVASIVE MEASUREMENT; PRENATAL DIAGNOSIS; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; TARGETED MASSIVELY PARALLEL SEQUENCING; TRISOMY 21; BLOOD; DOWN SYNDROME; GENETICS; HIGH THROUGHPUT SCREENING; METABOLISM; METHODOLOGY; MOTHER; PREGNANCY;

ALLELES; COMPUTER SIMULATION; DNA; DOWN SYNDROME; FEMALE; FETUS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MOTHERS; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PRENATAL DIAGNOSIS; SEQUENCE ANALYSIS, DNA;

EID: 84861553409     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038154     Document Type: Article

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