Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells

Human Reproduction

Volumn 27, Issue 6, 2012, Pages 1790-1800

  Reverchon, Maxime ^a   Cornuau, Marion ^b   Ram, Christelle ^a   Guerif, Fabrice ^a,b   Royre, Dominique ^a,b   Dupont, Jolle ^a  

^a UMR85 PHYSIOLOGIE DE LA REPRODUCTION ET DES COMPORTEMENTS   (France)

^b UNIVERSITY HOSPITAL OF TOURS   (France)

Author keywords

Adipokine; Growth factors; Ovary; Signalling pathways; Steroidogenesis

Indexed keywords

ADIPOCYTOKINE; AROMATASE; CHEMERIN; CHEMOKINE RECEPTOR CCR1; ESTRADIOL; FOLLITROPIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROGESTERONE; RECOMBINANT CHEMERIN; RECOMBINANT PROTEIN; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TYROSINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; DRUG EFFECT; ENZYME ACTIVATION; ESTROGEN RELEASE; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GRANULOSA CELL; GRANULOSA CELL TUMOR; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; OVARY FOLLICLE FLUID; PROGESTERONE RELEASE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEROIDOGENESIS;

EID: 84861548206     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des089     Document Type: Article

References (43)

1. Abir R, Ao A, Jin S, Barnett M, Raanani H, Ben-Haroush A, Fisch B. Leptin and its receptors in human fetal and adult ovaries. Fertil Steril 2005; 84:1779-1782.
2. Adashi EY. Endocrinology of the ovary. Hum Reprod 1994;9:815-827.
3. Adashi EY. The IGF family and folliculogenesis. J Reprod Immunol 1998; 39:13-19.
4. Bergh C, Olsson JH, Hillensjo T. Effect of insulin-like growth factor I on steroidogenesis in cultured human granulosa cells. Acta Endocrinol (Copenh) 1991;125:177-185.
5. Bozaoglu K, Bolton K, McMillan J, Zimmet P, Jowett J, Collier G,Walder K, Segal D. Chemerin is a novel adipokine associated with obesity and metabolic syndrome. Endocrinology 2007;148:4687-4694.
6. Bozaoglu K, Curran JE, Stocker CJ, Zaibi MS, Segal D, Konstantopoulos N, Morrison S, Carless M, Dyer TD, Cole SA et al. Chemerin, a novel adipokine in the regulation of angiogenesis. J Clin Endocrinol Metab 2010;95:2476-2485.
7. Brannstrom M, Norman RJ. Involvement of leukocytes and cytokines in the ovulatory process and corpus luteum function. Hum Reprod 1993; 8:1762-1775.
8. Chabrolle C, Tosca L, Rame C, Lecomte P, Royere D, Dupont J. Adiponectin increases insulin-like growth factor I-induced progesterone and estradiol secretion in human granulosa cells. Fertil Steril 2009;92:1988-1996.
9. Chen R, Fisch B, Ben-Haroush A, Kaplan B, Hod M, Orvieto R. Serum and follicular fluid leptin levels in patients undergoing controlled ovarian hyperstimulation for in vitro fertilization cycle. Clin Exp Obstet Gynecol 2004;31:103-106.
10. Chen YC, Tsai EM, Chen HS, Liu YH, Lee CH, Chou FH, Chen IJ, Chen SY, Jong SB, Chan TF. Serum resistin level is a predictor of ovarian response in in vitro fertilisation cycle. Acta Obstet Gynecol Scand 2007;86:963-967.
11. Dupont J, Karas M, LeRoith D. The potentiation of estrogen on insulin-like growth factor I action in MCF-7 human breast cancer cells includes cell cycle components. J Biol Chem 2000;275:35893-35901.
12. Ernst MC, Issa M, Goralski KB, Sinal CJ. Chemerin exacerbates glucose intolerance in mouse models of obesity and diabetes. Endocrinology 2010;151:1998-2007.
13. Gantz I, Konda Y, Yang YK, Miller DE, Dierick HA, Yamada T. Molecular cloning of a novel receptor (CMKLR1) with homology to the chemotactic factor receptors. Cytogenet Cell Genet 1996;74:286-290.
14. Goralski KB, McCarthy TC, Hanniman EA, Zabel BA, Butcher EC, Parlee SD, Muruganandan S, Sinal CJ. Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism. J Biol Chem 2007;282:28175-28188.
15. Goto M, Iwase A, Harata T, Takigawa S, Suzuki K, Manabe S, Kikkawa F. IGF1-induced AKT phosphorylation and cell proliferation are suppressed with the increase in PTEN during luteinization in human granulosa cells. Reproduction 2009;137:835-842.
16. Guerif F, Bidault R, Gasnier O, Couet ML, Gervereau O, Lansac J, Royere D. Efficacy of blastocyst transfer after implantation failure. Reprod Biomed Online 2004;9:630-636.
17. Gurbuz B, Yalti S, Ficicioglu C, Tasdemir S. The relation of serum and follicular fluid leptin and ovarian steroid levels in response to induction of ovulation in in vitro fertilization cycles. Eur J Obstet Gynecol Reprod Biol 2005;118:214-218.
18. Hegyi K, Fulop K, Kovacs K, Toth S, Falus A. Leptin-induced signal transduction pathways. Cell Biol Int 2004;28:159-169.
19. Hu W, Feng P. Elevated serum chemerin concentrations are associated with renal dysfunction in type 2 diabetic patients. Diabetes Res Clin Pract 2011;91:159-163.
20. Karamouti M, Kollia P, Karligiotou E, Kallitsaris A, Prapas N, Kollios G, Seferiadis K, Vamvakopoulos N, Messinis IE. Absence of leptin expression and secretion by human luteinized granulosa cells. J Mol Endocrinol 2003;31:233-239.
21. Maillard V, Froment P, Rame C, Uzbekova S, Elis S, Dupont J. Expression and effect of resistin on bovine and rat granulosa cell steroidogenesis and proliferation. Reproduction 2011;141:467-479.
22. Mantzoros CS, Cramer DW, Liberman RF, Barbieri RL. Predictive value of serum and follicular fluid leptin concentrations during assisted reproductive cycles in normal women and in women with the polycystic ovarian syndrome. Hum Reprod 2000;15:539-544.
23. Michalakis KG, Segars JH. The role of adiponectin in reproduction: from polycystic ovary syndrome to assisted reproduction. Fertil Steril 2010; 94:1949-1957.
24. Mitchell M, Armstrong DT, Robker RL, Norman RJ. Adipokines: implications for female fertility and obesity. Reproduction 2005; 130:583-597.
25. Moschos S, Chan JL, Mantzoros CS. Leptin and reproduction: a review. Fertil Steril 2002;77:433-444.
26. Nagpal S, Patel S, Jacobe H, DiSepio D, Ghosn C, Malhotra M, Teng M, Duvic M, Chandraratna RA. Tazarotene-induced gene 2 (TIG2), a novel retinoid-responsive gene in skin. J Invest Dermatol 1997; 109:91-95.
27. Nishi Y, Yanase T, Mu Y, Oba K, Ichino I, Saito M, Nomura M, Mukasa C, Okabe T, Goto K. Establishment and characterization of a steroidogenic human granulosa-like tumor cell line, KGN, that expresses functional follicle-stimulating hormone receptor. Endocrinology 2001; 142:437-445.
28. Parlee SD, Ernst MC, Muruganandan S, Sinal CJ, Goralski KB. Serum chemerin levels vary with time of day and are modified by obesity and tumor necrosis factor-{alpha}. Endocrinology 2010;151:2590-2602.
29. Pasceri V, Yeh ET. A tale of two diseases: atherosclerosis and rheumatoid arthritis. Circulation 1999;100:2124-2126.
30. Pierre P, Froment P, Negre D, Rame C, Barateau V, Chabrolle C, Lecomte P, Dupont J. Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN. Hum Reprod 2009;24:2890-2901.
31. Ress C, Tschoner A, Engl J, Klaus A, Tilg H, Ebenbichler CF, Patsch JR, Kaser S. Effect of bariatric surgery on circulating chemerin levels. Eur J Clin Invest 2010;40:277-280.
32. Richards JS, Russell DL, Ochsner S, Hsieh M, Doyle KH, Falender AE, Lo YK, Sharma SC. Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization. Recent Prog Horm Res 2002;57:195-220.
33. Roh SG, Song SH, Choi KC, Katoh K,Wittamer V, Parmentier M, Sasaki S. Chemerin-a new adipokine that modulates adipogenesis via its own receptor. Biochem Biophys Res Commun 2007;362:1013-1018.
34. Sell H, Laurencikiene J, Taube A, Eckardt K, Cramer A, Horrighs A, Arner P, Eckel J. Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells. Diabetes 2009;58:2731-2740.
35. Sell H, Divoux A, Poitou C, Basdevant A, Bouillot JL, Bedossa P, Tordjman J, Eckel J, Clement K. Chemerin correlates with markers for fatty liver in morbidly obese patients and strongly decreases after weight loss induced by bariatric surgery. J Clin Endocrinol Metab 2010; 95:2892-2896.
36. Seow KM, Juan CC, Hsu YP, Ho LT, Wang YY, Hwang JL. Serum and follicular resistin levels in women with polycystic ovarian syndrome during IVF-stimulated cycles. Hum Reprod 2005;20:117-121.
37. Seto-Young D, Zajac J, Liu HC, Rosenwaks Z, Poretsky L. The role of mitogen-activated protein kinase in insulin and insulin-like growth factor I (IGF-I) signaling cascades for progesterone and IGF-binding protein-1 production in human granulosa cells. J Clin Endocrinol Metab 2003;88:3385-3391.
38. Stepan H, Philipp A, Roth I, Kralisch S, Jank A, Schaarschmidt W, Lö ssner U, Kratzsch J, Blüher M, Stumvoll M et al. Fasshauer M. Serum levels of the adipokine chemerin are increased in preeclampsia during and 6 months after pregnancy. Regul Pept 2011; 168:69-72.
39. Tan BK, Chen J, Farhatullah S, Adya R, Kaur J, Heutling D, Lewandowski KC, O'Hare JP, Lehnert H, Randeva HS. Insulin and metformin regulate circulating and adipose tissue chemerin. Diabetes 2009;58:1971-1977.
40. Tosca L, Froment P, Solnais P, Ferre P, Foufelle F, Dupont J. Adenosine 5′-monophosphate-activated protein kinase regulates progesterone secretion in rat granulosa cells. Endocrinology 2005;146:4500-4513.
41. Wittamer V, Franssen JD, Vulcano M, Mirjolet JF, Le Poul E, Migeotte I, Brezillon S, Tyldesley R, Blanpain C, Detheux M et al. Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. J Exp Med 2003; 198:977-985.
42. Yoshimura T, Oppenheim JJ. Chemokine-like receptor 1 (CMKLR1) and chemokine (C-C motif) receptor-like 2 (CCRL2); two multifunctional receptors with unusual properties. Exp Cell Res 2011;317:674-684.
43. Zabel BA, Allen SJ, Kulig P, Allen JA, Cichy J, Handel TM, Butcher EC. Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades. J Biol Chem 2005; 280:34661-34666.