A novel "Reactomics" approach for cancer diagnostics

Sensors (Switzerland)

Volumn 12, Issue 5, 2012, Pages 5572-5585

  Kolusheva, Sofiya ^a   Yossef, Rami ^a   Kugel, Aleksandra ^a   Hanin Avraham, Nirit ^a   Cohen, Meital ^a   Rubin, Eitan ^a   Porgador, Angel ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

Author keywords

Bioinformatics; Biomarker; Cancer; Diagnostics; Polydiacetylene; Serum

Indexed keywords

ARTICLE; BLOOD; HUMAN; METABOLISM; NEOPLASM; SPECTROFLUOROMETRY;

HUMANS; NEOPLASMS; SPECTROMETRY, FLUORESCENCE;

EID: 84861538791     PISSN: 14248220     EISSN: None     Source Type: Journal    
DOI: 10.3390/s120505572     Document Type: Article

References (17)

1. Rai, A.J.; Chan, D.W. Cancer proteomics: Serum diagnostics for tumor marker discovery. Ann. N. Y. Acad. Sci. 2004, 1022, 286-294.
2. Diamandis, E.P. Cancer biomarkers: Can we turn recent failures into success? J. Natl. Cancer Inst. 2010, 102, 1462-1467.
3. Ransohoff, D.F. Promises and limitations of biomarkers. Recent Results Cancer Res. 2009, 181, 55-59.
4. Sikaroodi, M.; Galachiantz, Y.; Baranova, A. Tumor markers: The potential of "omics" approach. Curr. Mol. Med. 2010, 10, 249-257.
5. Kolusheva, S.; Wachtel, E.; Jelinek, R. Bio-mimetic lipid/polymer colorimetric membranes: Molecular and cooperative properties. J. Lipid Res. 2003, 44, 65-71.
6. Kolusheva, S.; Shahal, T.; Jelinek, R. Peptide-membrane interactions studied by a new phospholipid/polydiacetylene colorimetric vesicle assay. Biochemistry 2000, 39, 15851-15859.
7. Ringsdorf, H.; Schlarb, B.; Venzmer, J. Molecular architecture and function of polymeric oriented systems: Models for the study of organization, surface recognition, and dynamics of biomembranes. Angew. Chem. Int. Ed. 1988, 27, 113-158.
8. Hanin-Avraham, N.; Fuhrman, B.; Mech-Dorosz, A.; Kolusheva, S.; Porgador, A.; Aviram, M.; Jelinek, R. Lipoprotein interactions with chromatic membranes as a novel marker for oxidative stress-Related diseases. Biochim. Biophy. Acta Biomembr. 2009, 1788, 2436-2443.
9. Alpaydin, E. Introduction to Machine Learning; MIT Press: Cambridge, MA, USA, 2004.
10. Chang, C.C.; Lin, C.J. LIBSVM-A Library for Support Vector Machines, 2009. Available online: http://www.csie.ntu.edu.tw/~cjlin/libsvm/ (accessed on 3 February 2012).
11. Chen, J.; Anderson, M.; Misek, D.E.; Simeone, D.M.; Lubman, D.M. Characterization of apolipoprotein and apolipoprotein precursors in pancreatic cancer serum samples via two-dimensional liquid chromatography and mass spectrometry. J. Chromatogr. 2007, A1162, 117-125.
12. Yamamoto-Ishikawa, K.; Suzuki, H.; Nezu, M.; Kamiya, N.; Imamoto, T.; Komiya, A.; Sogawa, A.; Tomonaga, T.; Nomura, F.; Ichikawa, T. The isolation and identification of apolipoprotein C-I in hormone-refractory prostate cancer using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry. Asian J. Androl. 2009, 11, 299-307.
13. Engwegen, J.Y.; Helgason, H.H.; Cats, A.; Harris, N.; Bonfrer, J.M.; Schellens, J.H.; Beijnen, J.H. Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry. World J. Gastroenterol. 2006, 12, 1536-1544.
14. Gobel, T.; Vorderwulbecke, S.; Hauck, K.; Fey, H.; Haussinger, D.; Erhardt, A. New multi protein patterns differentiate liver fibrosis stages and hepatocellular carcinoma in chronic hepatitis C serum samples. World J. Gastroenterol. 2006, 12, 7604-7612.
15. McComb, M.E.; Perlman, D.H.; Huang, H.; Costello, C.E. Evaluation of an on-target sample preparation system for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in conjunction with normal-flow peptide high-performance liquid chromatography for peptide mass fingerprint analyses. Rapid Commun. Mass. Spectrom. 2006, 21, 44-58.
16. Gennis, R.B. Biomembranes: Molecular Structure and Function; Springer: New York, NY, USA, 1989.
17. Cohen, M.; Yossef, R.; Erez, T.; Kugel, A.; Welt, M.; Karpasas, M.M.; Bones, J.; Rudd, P.M.; Taieb, J.; Boissin, H.; Harats, D.; Noy, K.; Tekoah, Y.; Lichtenstein, R.G.; Rubin, E.; Porgador, A. Serum apolipoproteins C-I and C-III are reduced in stomach cancer patients: Results from MALDI-based peptidome and immuno-based clinical assays. PLoS One 2011, doi: 10.1371/journal.pone.0014540.