The views of patients and healthy volunteers on participation in clinical trials: An exploratory survey study

Contemporary Clinical Trials

Volumn 33, Issue 4, 2012, Pages 611-619

  Chu, Sang Hui ^a   Jeong, Seok Hee ^b   Kim, Eun Jung ^c   Park, Min Soo ^d   Park, Kyungsoo ^e   Nam, Moonsuk ^f   Shim, Jae Yong ^g   Yoon, Young Ran ^h  

^a Yonsei University   (South Korea)

^b Chonbuk National University   (South Korea)

^c Eulji University   (South Korea)

^d Yonsei University College of Medicine   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f Inha University Hospital   (South Korea)

^g Yonsei University College of Medicine   (South Korea)

^h Kyungpook National University Hospital   (South Korea)

Author keywords

Clinical trials; Healthy subjects; Patient; Views

Indexed keywords

ADULT; ARTICLE; BIOEQUIVALENCE; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; ECONOMIC ASPECT; EXPLORATORY RESEARCH; FEMALE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL PERSONNEL; OUTPATIENT DEPARTMENT; PATIENT ATTITUDE; PATIENT DECISION MAKING; PATIENT PARTICIPATION; PATIENT SATISFACTION; PERCEPTION; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PHASE 4 CLINICAL TRIAL (TOPIC); PHYSICIAN; SOUTH KOREA; STRUCTURED QUESTIONNAIRE; UNIVERSITY HOSPITAL; WARD;

ADULT; AGED; ATTITUDE TO HEALTH; CLINICAL TRIALS AS TOPIC; FEMALE; HEALTH CARE SURVEYS; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; INFORMED CONSENT; MALE; MIDDLE AGED; PATIENT PARTICIPATION; PATIENT SATISFACTION; PATIENTS; PROFESSIONAL-PATIENT RELATIONS; QUESTIONNAIRES; REPUBLIC OF KOREA; VOLUNTARY WORKERS;

EID: 84861531182     PISSN: 15517144     EISSN: 15592030     Source Type: Journal    
DOI: 10.1016/j.cct.2012.02.018     Document Type: Article

References (13)

1. Thiers F.A., Sinskey A.J., Berndt E.R. Trends in the globalization of clinical trials. Nat Rev Drug Discov 2008, 7:13-14.
2. Russell M.L., Moralejo D.G., Burgess E.D. Paying research subjects: participants' perspectives. J Med Ethics 2000, 26:126-130.
3. Ross S., Grant A., Counsell C., Gillespie W., Russell I., Prescott R. Barriers to participation in randomised controlled trials: a systematic review. J Clin Epidemiol 1999, 52:1143-1156.
4. Ellis P.M. Attitudes towards and participation in randomised clinical trials in oncology: a review of the literature. Ann Oncol 2000, 11:939-945.
5. Fallowfield L.J., Jenkins V., Brennan C., Sawtell M., Moynihan C., Souhami R.L. Attitudes of patients to randomised clinical trials of cancer therapy. Eur J Cancer 1998, 34:1554-1559.
6. Ulrich C.M., James J.L., Walker E.M., Stine S.H., Gore E., Prestidge B., et al. RTOG physician and research associate attitudes, beliefs and practices regarding clinical trials: implications for improving patient recruitment. Contemp Clin Trials 2010, 31:221-228. 10.1016/j.cct.2010.03.002.
7. Comis R.L., Miller J.D., Colaizzi D.D., Kimmel L.G. Physician-related factors involved in patient decisions to enroll onto cancer clinical trials. J Oncol Pract 2009, 5:50-56. 10.1200/JOP.0922001.
8. Mills E.J., Seely D., Rachlis B., Griffith L., Wu P., Wilson K., et al. Barriers to participation in clinical trials of cancer: a meta-analysis and systematic review of patient-reported factors. Lancet Oncol 2006, 7:141-148. 10.1016/S1470-2045(06)70576-9.
9. Stepan K.A., Gonzalez A.P., Dorsey V.S., Frye D.K., Pyle N.D., Smith R.F., et al. Recommendations for enhancing clinical trials education: a review of the literature. J Cancer Educ 2011, 26:64-71. 10.1007/s13187-010-0160-4.
10. Brown R.F., Shuk E., Leighl N., Butow P., Ostroff J., Edgerson S., et al. Enhancing decision making about participation in cancer clinical trials: development of a question prompt list. Support Care Cancer 2011, 19:1227-1238. 10.1007/s00520-010-0942-6.
11. Stryker J.E., Wray R.J., Emmons K.M., Winer E., Demetri G. Understanding the decisions of cancer clinical trial participants to enter research studies: factors associated with informed consent, patient satisfaction, and decisional regret. Patient Educ Couns 2006, 63:104-109. 10.1016/j.pec.2005.09.006.
12. Comis R.L., Miller J.D., Aldige C.R., Krebs L., Stoval E. Public attitudes toward participation in cancer clinical trials. J Clin Oncol 2003, 21:830-835.
13. Cox K., Moghaddam N., Bird L., Elkan R. Feedback of trial results to participants: a survey of clinicians' and patients' attitudes and experiences. Eur J Oncol Nurs 2011, 15:124-129. 10.1016/j.ejon.2010.06.009.