Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163

Journal of Controlled Release

Volumn 160, Issue 1, 2012, Pages 72-80

  Etzerodt, Anders ^a   Maniecki, MacIej Bogdan ^b   Graversen, Jonas Heilskov ^c   Moller, Holger Jon ^b   Torchilin, Vladimir P ^d   Moestrup, Soren Kragh ^a,b  

^a AARHUS UNIVERSITY   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c Cytoguide ApS   (Denmark)

^d NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Cancer; CD163; Inflammation; Macrophage; Stealth liposomes; Tumor associated macrophages

Indexed keywords

CALCEIN; CANCER; CD163; CHEMOTHERAPEUTIC AGENTS; CYTOTOXIC EFFECTS; DOXORUBICIN; DRUG-TARGETING; HUMAN MONOCYTES; INFLAMMATION; SCAVENGER RECEPTOR; STEALTH LIPOSOMES; TRANSFECTED CELLS; TUMOR GROWTH;

CONFOCAL MICROSCOPY; CYTOTOXICITY; FLOW CYTOMETRY; HEMOGLOBIN; MACROPHAGES; MONOCLONAL ANTIBODIES; PATHOLOGY; POLYETHYLENE GLYCOLS; TUMORS;

LIPOSOMES;

CALCEIN; CD163 ANTIGEN; DOXORUBICIN; LIPOSOME; LONG CIRCULATING LIPOSOME; MACROGOL; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ARTICLE; CELL TYPE; CONFOCAL MICROSCOPY; CYTOTOXICITY; DRUG TARGETING; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BINDING SITES; CELL CULTURE TECHNIQUES; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCEINS; HEK293 CELLS; HEMOGLOBINS; HUMANS; LIPOSOMES; MACROPHAGES; MICROSCOPY, CONFOCAL; RECEPTORS, CELL SURFACE; RECEPTORS, SCAVENGER; SURFACE PLASMON RESONANCE;

EID: 84861526023     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.01.034     Document Type: Article

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