Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism?

Andrologia

Volumn 44, Issue SUPPL.1, 2012, Pages 226-230

  Tambi, Mohd Ismail Bin Mohd ^a,b   Imran, M K ^b   Henkel, R R ^c  

^a Damai Service Hospital   (Malaysia)

^b SCHOOL OF PHYSICS   (Malaysia)

^c UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

Adaptogen; Eurycoma longifolia; Hypogonadism; Late onset hypogonadism; Testosterone; Tongkat ali

Indexed keywords

EURYCOMA LONGIFOLIA EXTRACT; TESTOSTERONE;

AGING; AGING MALE SYNDROME; ARTICLE; ENDOCRINE DISEASE; HUMAN; HYPOGONADISM; MAJOR CLINICAL STUDY; MALE; TESTOSTERONE BLOOD LEVEL; TREATMENT DURATION;

AGED; EURYCOMA; HUMANS; HYPOGONADISM; MALE; PLANT EXTRACTS; TESTOSTERONE; WATER;

EID: 84861520215     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/j.1439-0272.2011.01168.x     Document Type: Article

References (34)

1. Ali JM, Saad JM (1993) Biochemical effect of Eurycoma Longifolia Jack on the sexual behavior, fertility, sex hormone and glycolysis [Dissertation]. Department of Biochemistry, University of Malaya.
2. Ang HH, Lee KL (2002) Effect of Eurycoma longifolia Jack on orientation activities in middle-aged male rats. Fundam Clin Pharmacol16:479-483.
3. Ang HH, Ngai TH (2001) Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack. Fundam Clin Pharmacol15:265268.
4. Ang HH, Sim MK (1997) Eurycoma longifolia Jack enhances libido in sexually experienced male rats. Exp Anim46:287-290.
5. Ang HH, Sim MK (1998a) Eurycoma longifolia increases sexual motivation in sexually naive male rats. Arch Pharm Res21:779-781.
6. Ang HH, Sim MK (1998b) Eurycoma longifolia Jack and orientation activities in sexually experienced male rats. Biol Pharm Bull21:153-155.
7. Ang HH, Cheang HS, Yusof AP (2000) Effects of Eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats. Exp Anim49:35-38.
8. Ang HH, Hitotsuyanagi Y, Fukuya H, Takeya K (2002) Quassinoids from Eurycoma longifolia. Phytochemistry59:833-837.
9. Ang HH, Ngai TH, Tan TH (2003) Effects of Eurycoma longifolia Jack on sexual qualities in middle aged male rats. Phytomedicine10:590-593.
10. Asiah O, Nurhanan MY, Ilham MA (2007) Determination of bioactive peptide (4.3kDa) as an aphrodisiac marker in six Malaysia plants. J Tropical Forest Sci19:61-63.
11. Bedir E, Abou-Gazar H, Ngwendson JN, Khan IA (2003) Eurycomaoiside: a new quassinoid-type glycoside from the root of Eurycoma longifolia. Chem Pharm Bull (Tokyo)51:1301-1303.
12. Bhat R, Karim AA (2010) Tongkat ali (Eurycoma longifolia Jack): a review on its ethnobotany and pharmacological importance. Fitoterapia10:1-11.
13. Bratman S, Girman A (2003) Mosby's Handbook of Herbs and Supplements and their Therapeutic Uses. Mosby Inc., St. Louis, MO, pp 976-978.
14. Castleman M (1995) Healing Herbs. Bantam Books, New York, pp 1-5.
15. Ernst E (2000) The role of complementary and alternative medicine. BMJ321:1133-1135.
16. Gonzales GF, Valerio LG Jr (2006) Medicinal plants from Peru: a review of plants as potential agents against cancer. Anticancer Agents Med Chem6:429-444.
17. Gonzales GF, Cordova A, Vega K, Chung A, Villena A, Gonez C, Castillo S (2002) Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia34:367-372.
18. Hamzah S, Yusof A (2003) The ergogenic effects of Tongkat Ali (Eurycoma longifolia). Br J Sports Med37:465-466.
19. Heinemann LAJ, Zimmermann T, Vermeulen A, Thiel C (1999) A new 'Aging Male's Symptoms' (AMS) rating scale. The Aging Male2:105-114.
20. Jockenhövel F (2004) Male Hypogonadism. Uni-Med Verlag, Bremen, Germany, pp 118-134.
21. Lin LC, Peng CY, Wang HS, Lee KWW (2001) Reinvestigation of the chemical constituents of Eurycoma longifolia. Chin Pharm J53:97-106.
22. Low WY, Tan HM (2007) Asian traditional medicine for erectile dysfunction. JMHG4:245-250.
23. MacKay D (2004) Nutrients and botanicals for erectile dysfunction: examining the evidence. Altern Med Rev9:4-16.
24. Morita H, Kishi E, Takeya K, Itokawa H, Iitaka Y (1993) Squalene derivatives from Eurycoma longifolia. Phytochemistry4:765-771.
25. Nocerino E, Amato M, Izzo AA (2000) The aphrodisiac and adaptogenic properties of ginseng. Fitoterapia71:S1-S5.
26. Perry LM, Metzger J (1980) Medicinal Plants of Southeast Asia: Attributed Properties and Uses. MIT Press, Cambridge.
27. Sambandan TG, Rha C, Aminudim N, Saad JM, Kadir AA (2006) Bioactive fraction of Eurycoma longifolia. Patent number: WO0217946; Other reference numbers: JP2004521075, US2004087493, EP1313491, DK1313491, DE60125955.
28. Tambi MI (2006) Eurycoma Longifolia Jack: a potent adaptogen in the form of water-soluble extract with the effect of maintaining men's health. Asian J Androl8(Suppl. 1):49-50.
29. Tambi MI (2009) Nutrients and botanicals for optimizing men's health. Examining the evidence for Eurycoma longifolia Jack, the Malaysian Ginseng in men. Asian J Androl11(Suppl. 5):37-38.
30. Tambi MI, Imran MK (2010) Eurycoma longifolia Jack in managing idiopathic male infertility. Asian J Androl12:376-380.
31. Valerio LG Jr, Gonzales GF (2005) Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii): a critical synopsis. Toxicol Rev24:11-35.
32. Van Wyk B, Van Oudtshoorn B, Gericke N (1997) Medicinal Plants of South Africa. Briza Publishers, Pretoria, South Africa.
33. Wang C, Nieschlag E, Swerdloff R, Behre HM, Hellstrom WJ, Gooren LJ, Kaufman JM, Legros JJ, Lunenfeld B, Morales A, Morley JE, Schulman C, Thompson IM, Weidner W, Wu FCW (2008) Investigation, treatment and monitoring of late-onset hypogonadism in males. ISA, ISSAM, EAU, EAA and ASA recommendations. Eur J Endocrinol159:507-514.
34. Zanoli P, Zavatti M, Montanari C, Baraldi M (2009) Influence of Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats. J Ethnopharmacol126:308-313.