Doppler ultrasound and D-dimer: Friend or foe?

Hamostaseologie

Volumn 32, Issue 1, 2012, Pages 28-36

  Riopel, C ^a   Bounameaux, H ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Clinical probability; D dimer; Deep vein thrombosis; Ultrasonography

Indexed keywords

D DIMER;

COMPUTED TOMOGRAPHIC ANGIOGRAPHY; DEEP VEIN THROMBOSIS; DOPPLER FLOWMETRY; ECHOGRAPHY; HUMAN; LUNG EMBOLISM; NEOPLASM; OUTCOME ASSESSMENT; REVIEW; VENOUS THROMBOEMBOLISM;

FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; ULTRASONOGRAPHY, DOPPLER; VENOUS THROMBOEMBOLISM;

EID: 84861512873     PISSN: 07209355     EISSN: None     Source Type: Journal    
DOI: 10.5482/ha-1182     Document Type: Review

References (61)

1. Roy PM, Meyer G, Vielle B et al. Appropriateness of diagnostic management and outcomes of suspected pulmonary embolism. Ann Intern Med 2006; 144: 157-164.
2. Brown MD, Rowe BH, Reeves MJ et al. The accuracy of the enzyme-linked immunosorbent assay D-dimer test in the diagnosis of pulmonary embolism: a meta-analysis. Ann Emerg Med 2002; 40: 133-144.
3. Di Nisio M, Squizzato A, Rutjes AW et al. Diagnostic accuracy of D-dimer test for exclusion of venous thromboembolism: a systematic review. J Thromb Haemost 2007; 5: 296-304.
4. Pittet JL, de Moerloose P, Reber G et al. VIDAS D-dimer: fast quantitative ELISA for measuring D-dimer in plasma. Clin Chem 1996; 42: 410-415.
5. Brown MD, Lau J, Nelson RD, Kline JA. Turbidimetric D-dimer test in the diagnosis of pulmonary embolism: a metaanalysis. Clin Chem 2003; 49: 1846-1853.
6. De Monye W, Huisman MV, Pattynama PM. Observer dependency of the SimpliRed D-dimer assay in 81 consecutive patients with suspected pulmonary embolism. Thromb Res 1999; 96: 293-298.
7. Chunilal SD, Eikelboom JW, Attia J et al. Does this patient have pulmonary embolism? JAMA 2003; 290: 2849-2858.
8. Rodger MA, Maser E, Stiell I et al. The interobserver reliability of pretest probability assessment in patients with suspected pulmonary embolism. Thromb Res 2005; 116: 101-107.
9. Wells PS, Anderson DR, Bormanis J et al. Value of assessment of pretest probability of deep-vein thrombosis in clinical management. Lancet 1997; 350: 1795-1798.
10. Wells PS, Anderson DR, Rodger M et al. Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer. Thromb Haemost 2000; 83: 416-420.
11. Wicki J, Perneger TV, Junod AF et al. Assessing clinical probability of pulmonary embolism in the emergency ward: a simple score. Arch Intern Med 2001; 161: 92-97.
12. Chagnon I, Bounameaux H, Aujesky D et al. Comparison of two clinical prediction rules and implicit assessment among patients with suspected pulmonary embolism. Am J Med 2002; 113: 269-275.
13. Le Gal G, Righini M, Roy PM et al. Prediction of pulmonary embolism in the emergency department: the revised Geneva score. Ann Intern Med 2006; 144: 165-171.
14. Klok FA, Kruisman E, Spaan J et al. Comparison of the revised Geneva score with the Wells rule for assessing clinical probability of pulmonary embolism. J Thromb Haemost 2008; 6: 40-44.
15. Righini M, Le Gal G, Aujesky D et al. Diagnosis of pulmonary embolism by multidetector CT alone or combined with venous ultrasonography of the leg: a randomised non-inferiority trial. Lancet 2008; 371: 1343-1352.
16. Anderson DR, Kahn SR, Rodger MA et al. Computed tomographic pulmonary angiography vs ventilation-perfusion lung scanning in patients with suspected pulmonary embolism: a randomized controlled trial. JAMA 2007; 298: 2743-2753.
17. Van Belle A, Buller HR, Huisman MV et al. Effectiveness of managing suspected pulmonary embolism using an algorithm combining clinical probability, D-dimer testing, and computed tomography. JAMA 2006; 295: 172-179.
18. Ceriani E, Combescure C, Le Gal G et al. Clinical prediction rules for pulmonary embolism: a systematic review and meta-analysis. J Thromb Haemost 2010; 8: 957-970.
19. Carrier M, Righini M, Djurabi RK et al. VIDAS D-dimer in combination with clinical pre-test probability to rule out pulmonary embolism. A systematic review of management outcome studies. Thromb Haemost 2009; 101: 886-892.
20. Kruip MJ, Slob MJ, Schijen JH et al. Use of a clinical decision rule in combination with D-dimer concentration in diagnostic workup of patients with suspected pulmonary embolism: a prospective management study. Arch Intern Med 2002; 162: 1631-1635.
21. Perrier A, Desmarais S, Miron MJ et al. Non-invasive diagnosis of venous thromboembolism in outpatients. Lancet 1999; 353: 190-195.
22. Ten Wolde M, Hagen PJ, Macgillavry MR et al. Noninvasive diagnostic work-up of patients with clinically suspected pulmonary embolism; results of a management study. J Thromb Haemost 2004; 2: 1110-1117.
23. Miron MJ, Perrier A, Bounameaux H et al. Contribution of noninvasive evaluation to the diagnosis of pulmonary embolism in hospitalized patients. Eur Respir J 1999; 13: 1365-1370.
24. Righini M, Goehring C, Bounameaux H, Perrier A. Effects of age on the performance of common diagnostic tests for pulmonary embolism. Am J Med 2000; 109: 357-361. Epub 2000/10/06.
25. Righini M, Le Gal G, Perrier A, Bounameaux H. The challenge of diagnosing pulmonary embolism in elderly patients: influence of age on commonly used diagnostic tests and strategies. J Am Geriatr Soc 2005; 53: 1039-1045.
26. Righini M, Nendaz M, Le Gal G et al. Influence of age on the cost-effectiveness of diagnostic strategies for suspected pulmonary embolism. J Thromb Haemost 2007; 5: 1869-1877.
27. Douma RA, Le Gal G, Sohne M et al. Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohorts. Br Med J 2010; 340: c1475.
28. Carrier M, Lee AY, Bates SM et al. Accuracy and usefulness of a clinical prediction rule and D-dimer testing in excluding deep vein thrombosis in cancer patients. Thromb Res 2008; 123: 177-183.
29. Righini M, Le Gal G, De Lucia S et al. Clinical usefulness of D-dimer testing in cancer patients with suspected pulmonary embolism. Thromb Haemost 2006; 95: 715-719.
30. Ten Wolde M, Kraaijenhagen RA, Prins MH, Buller HR. The clinical usefulness of D-dimer testing in cancer patients with suspected deep venous thrombosis. Arch Intern Med 2002; 162: 1880-1884.
31. Di Nisio M, Sohne M, Kamphuisen PW, Buller HR. D-Dimer test in cancer patients with suspected acute pulmonary embolism. J Thromb Haemost 2005; 3: 1239-1242.
32. D'Angelo A, D'Alessandro G, Tomassini L et al. Evaluation of a new rapid quantitative D-dimer assay in patients with clinically suspected deep vein thrombosis. Thromb Haemost 1996; 75: 412-416.
33. Couturaud F, Kearon C, Bates SM, Ginsberg JS. Decrease in sensitivity of D-dimer for acute venous thromboembolism after starting anticoagulant therapy. Blood Coagul Fibrinolysis 2002; 13: 241-246.
34. Le Gal G, Righini M, Roy PM et al. Value of D-dimer testing for the exclusion of pulmonary embolism in patients with previous venous thromboembolism. Arch Intern Med 2006; 166: 176-180.
35. De Monye W, Sanson BJ, Mac Gillavry MR et al. Embolus location affects the sensitivity of a rapid quantitative D-dimer assay in the diagnosis of pulmonary embolism. Am J Respir Crit Care Med 2002; 165: 345-348.
36. Sijens PE, van Ingen HE, van Beek EJ et al. Rapid ELISA assay for plasma D-dimer in the diagnosis of segmental and subsegmental pulmonary embolism. A comparison with pulmonary angiography. Thromb Haemost 2000; 84: 156-159.
37. Jennersjo CM, Fagerberg IH, Karlander SG, Lindahl TL. Normal D-dimer concentration is a common finding in symptomatic outpatients with distal deep vein thrombosis. Blood Coagul Fibrinolysis 2005; 16: 517-523.
38. Bosson JL, Barro C, Satger B et al. Quantitative high D-dimer value is predictive of pulmonary embolism occurrence independently of clinical score in a well-defined low risk factor population. J Thromb Haemost 2005; 3: 93-99.
39. Douma RA, Kessels JB, Buller HR, Gerdes VE. Knowledge of the D-dimer test result influences clinical probability assessment of pulmonary embolism. Thromb Res 2010; 126: e271-e275.
40. Birdwell BG, Raskob GE,X Whitsett TL et al. The clinical validity of normal compression ultrasonography in outpatients suspected of having deep venous thrombosis. Ann Intern Med 1998; 128: 1-7.
41. Cogo A, Lensing AW, Koopman MM et al. Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study. Br Med J 1998; 316: 17-20.
42. Bernardi E, Prandoni P, Lensing AW et al. D-dimer testing as an adjunct to ultrasonography in patients with clinically suspected deep vein thrombosis: prospective cohort study. The Multicentre Italian D-dimer Ultrasound Study Investigators Group. Br Med J 1998; 317: 1037-1040.
43. Kraaijenhagen RA, Piovella F, Bernardi E et al. Simplification of the diagnostic management of suspected deep vein thrombosis. Arch Intern Med 2002; 162: 907-911.
44. Righini M, Paris S, Le Gal G et al. Clinical relevance of distal deep vein thrombosis. Review of literature data. Thromb Haemost 2006; 95: 56-64.
45. Perone N, Bounameaux H, Perrier A. Comparison of four strategies for diagnosing deep vein thrombosis: a cost-effectiveness analysis. Am J Med 2001; 110: 33-40.
46. Elias A, Mallard L, Elias M et al. A single complete ultrasound investigation of the venous network for the diagnostic management of patients with a clinically suspected first episode of deep venous thrombosis of the lower limbs. Thromb Haemost 2003; 9: 221-227.
47. Schellong SM, Schwarz T, Halbritter K et al. Complete compression ultrasonography of the leg veins as a single test for the diagnosis of deep vein thrombosis. Thromb Haemost 2003; 89: 228-234.
48. Stevens SM, Elliott CG, Chan KJ et al. Withholding anticoagulation after a negative result on duplex ultrasonography for suspected symptomatic deep venous thrombosis. Ann Intern Med 2004; 140: 985-991.
49. Subramaniam RM, Chou T, Heath R, Allen R. Importance of pretest probability score and D-dimer assay before sonography for lower limb deep venous thrombosis. AJR Am J Roentgenol 2006; 186: 206-212.
50. Johnson SA, Stevens SM, Woller SC et al. Risk of deep vein thrombosis following a single negative whole-leg compression ultrasound: a systematic review and meta-analysis. JAMA 2010; 303: 438-445.
51. Righini M. Is it worth diagnosing and treating distal deep vein thrombosis? No. J Thromb Haemost 2007; 5 (Suppl 1): 55-59.
52. Righini M, Bounameaux H. Clinical relevance of distal deep vein thrombosis. Curr Opin Pulm Med 2008; 14: 408-413.
53. Quere I, Galanaud JP, Becker F et al. Distal deep-venous thrombosis: diagnostic and therapeutic issues. Rev Med Interne 2008; 29: 491-497.
54. th ed). Chest 2008; 133(6 Suppl): 454S-545S.
55. Bernardi E, Camporese G, Buller HR et al. Serial 2-point ultrasonography plus D-dimer vs wholeleg color-coded Doppler ultrasonography for diagnosing suspected symptomatic deep vein thrombosis: a randomized controlled trial. JAMA 2008; 300: 1653-1659.
56. Kearon C, Julian JA, Newman TE, Ginsberg JS. Noninvasive diagnosis of deep venous thrombosis. McMaster Diagnostic Imaging Practice Guidelines Initiative. Ann Intern Med 1998; 128: 663-677.
57. Goodacre S, Sampson F, Thomas S et al. Systematic review and meta-analysis of the diagnostic accuracy of ultrasonography for deep vein thrombosis. BMC Med Imaging 2005; 5: 6.
58. Kassai B, Boissel JP, Cucherat M et al. A systematic review of the accuracy of ultrasound in the diagnosis of deep venous thrombosis in asymptomatic patients. Thromb Haemost 2004; 91: 655-666.
59. Schellong SM. Venous ultrasonography in symptomatic and asymptomatic patients: an updated review. Curr Opin Pulm Med 2008; 14: 374-380.
60. Prandoni P, Cogo A, Bernardi E et al. A simple ultrasound approach for detection of recurrent proximal-vein thrombosis. Circulation 1993; 88: 1730-1735.
61. Heijboer H, Jongbloets LM, Buller HR et al. Clinical utility of real-time compression ultrasonography for diagnostic management of patients with recurrent venous thrombosis. Acta Radiol 1992; 33: 297-300.