Electrocardiographic changes during vasodilator SPECT myocardial perfusion imaging: Does it affect diagnosis or prognosis?

Journal of Nuclear Cardiology

Volumn 19, Issue 1, 2012, Pages 84-91

  Azemi, Talhat ^a   Rai, Mridula ^a,b   Parwani, Purvi ^a,b   Baghdasarian, Sarkis ^c   Kazi, Fawad ^a   Ahlberg, Alan W ^a   Cyr, Giselle ^a   Katten, Deborah ^a   O'Sullivan, David ^a   Fram, Daniel ^a   Heller, Gary V ^a  

^a Henry Low Heart Center   (United States)

^b UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Coronary artery disease; Diagnosis and prognosis application; Outcomes research; SPECT; Vasodilator stress

Indexed keywords

ADENOSINE; DIPYRIDAMOLE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; DIAGNOSTIC AGENT; VASODILATOR AGENT;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; DIAGNOSTIC VALUE; ELECTROCARDIOGRAM; EVENT FREE SURVIVAL; FEMALE; FOLLOW UP; HEART DEATH; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HUMAN; MAJOR CLINICAL STUDY; MALE; MYOCARDIAL PERFUSION IMAGING; PHARMACOLOGIC STRESS TESTING; PRIORITY JOURNAL; PROGNOSIS; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; ST SEGMENT DEPRESSION; ELECTROCARDIOGRAPHY; EXERCISE TEST; INCIDENCE; METHODOLOGY; MIDDLE AGED; MORTALITY; RISK ASSESSMENT; RISK FACTOR; STATISTICS; SURVIVAL; SURVIVAL RATE; UNITED STATES;

ADENOSINE; AGED; CONNECTICUT; CORONARY ARTERY DISEASE; DIPYRIDAMOLE; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MYOCARDIAL PERFUSION IMAGING; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SURVIVAL ANALYSIS; SURVIVAL RATE; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; VASODILATOR AGENTS;

EID: 84861498481     PISSN: 10713581     EISSN: 15326551     Source Type: Journal    
DOI: 10.1007/s12350-011-9457-x     Document Type: Article

References (34)

1. Wackers FJ, Russo DJ, Russo D, Clements JP. Prognostic significance of normal quantitative planar thallium-201 stress scintigraphy in patients with chest pain. J Am Coll Cardiol. 1985;6:27-30. (Pubitemid 15069237)
2. Krishnan R, Lu J, Daw MW, Botvinick EH. Does myocardial perfusion scintigraphy demonstrate clinical usefulness in patients with markedly positive exercise tests? An assessment of the method in a high risk subset. Am Heart J. 1994;127:804-16. (Pubitemid 24140017)
3. Raiker K, Sinusas AJ, Wackers FJ, Zaret BL. One-year prognosis of patients with normal planar or SPECT technetium 99m-labeled sestamibi exercise imaging. J Nucl Cardiol. 1994;1:449-56. (Pubitemid 24330041)
4. Hachamovitch R, Berman DS, Kiat H, Cohen I, Lewin H, Amanullah A, et al. Incremental prognostic value of adenosine stress myocardial perfusion SPECT and impact on subsequent management in patients with or suspected of having myocardial ischemia. Am J Cardiol. 1997;80:426-33. (Pubitemid 27371746)
5. Hachamovitch R, Berman DS, Shaw LJ, Kiat H, Cohen I, Cabico JA, et al. Incremental prognostic value of myocardial perfusion SPECT for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. Circulation. 1998;97:535-43. (Pubitemid 28090682)
6. Gibbons RJ, Hodge DO, Berman DS, Akinboboye OO, Heo J, Hachamovitch R, et al. Long-term outcome of patients with intermediate-risk exercise electrocardiograms who do not have myocardial perfusion defects on radionuclide imaging. Circulation. 1999;100:2140-5.
7. Verani MS, Mahmarian JJ, Hixson JB, Boyce TM, Staudacher RA. Diagnosis of coronary artery disease with adenosine and thallium- 201 scintigraphy in patients unable to exercise. Circulation. 1990;82:80-7. (Pubitemid 20216318)
8. Laarman G, Verzijllbergen JF, Ascoop CA. Ischemic ST changes after dipyridamole infusion. Int J Cardiol. 1987;14:384.
9. Chambers CE, Brown KA. Dipyridamole-induced ST segment depressing during thallium-201 imaging in patients with coronary artery disease: Angiographic and hemodynamic determinants. J Am Coll Cardiol. 1988;12:7-41.
10. Nguyen T, Heo J, Ogilby JD, Iskandrian AS. SPECT with thallium-201 during adenosine-induced coronary hyperemia: Correlation with coronary arteriography, exercise thallium and two-dimensional echocardiography. J Am Coll Cardiol. 1990;16: 1375-83.
11. Iskandrian AS, Heo J, Nguyen T, Beer SG, Cave V, Ogilby JD, et al. Assessment of coronary artery disease using SPECT with thallium-201 during adenosine induced coronary hyperemia. Am J Cardiol. 1991;67:1190-4.
12. Klodas E, Miller TD, Christian TF, Hodge DO, Gibbons RJ. Prognostic significance of ischemic electrocardiographic changes during vasodilator stress testing in patients with normal SPECT images. J Nucl Cardiol. 2003;10:4-8. (Pubitemid 36335846)
13. Abbott BG, Afshar M, Berger AK, Wackers FJ. Prognostic significance of ischemic electrocardiographic changes during adenosine infusion in patients with normal myocardial perfusion imaging. J Nucl Cardiol. 2003;10:9-16. (Pubitemid 36335847)
14. Hage F, Dubovsky E, Jaekyeong H, Iskandrian A. Outcome of patients with adenosine-induced ST-segment depression but with normal perfusion on tomographic imaging. Am J Cardiol. 2006; 98:1009-11. (Pubitemid 44486135)
15. Sharma J, Roncari C, Giedd KN, Fox JT, Kanei Y. Patients with adenosine-induced ST-segment depressions and normal myocardial perfusion imaging: Cardiac outcomes at 24 months. J Nucl Cardiol. 2010;17:874-80.
16. Henzlova MJ, Cerqueira MD, Mahmarian JJ, Yao SS. Quality Assurance Committee of the American Society of Nuclear Cardiology. Stress protocols and tracers. J Nucl Cardiol. 2006;13:e80-90.
17. American Society of Nuclear Cardiology. Imaging guidelines for nuclear cardiology procedures, part 2. JNuclCardiol. 1999;6:G47-84.
18. Cerqueria MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002;105:539-42. (Pubitemid 34262671)
19. Sharir T,GermanoG,KavanaughPB,Lai S,Cohen I,LewinHC, et al. Incremental prognostic value of post-stress left ventricular ejection fraction and volume by gated myocardial perfusion single photon emission computed tomography. Circulation. 1999;100:1035-42. (Pubitemid 29416228)
20. Petix NR, Sestini S, Marcucci G, Coppola A, Arena A, Nassi F, et al. Can the reversible regional wall motion abnormalities on stress gated Tc-99m sestamibi SPECT predict a future cardiac event? J Nucl Cardiol. 2005;12:20-31.
21. Petix NR, Sestini S, Coppola A, Marcucci G, Nassi F, Taiti A, et al. Prognostic value of combined perfusion and function by stress technetium-99m sestamibi gated SPECT myocardial perfusion imaging in patients with suspected or known coronary artery disease. Am J Cardiol. 2005;95:1351-7. (Pubitemid 40719868)
22. Stratmann HG, Younis LT, Wittry MD, Amato M, Miller DD. Dipyridamole technetium-99m sestamibi myocardial tomography in patients evaluated for elective vascular surgery: Prognostic value of perioperative and late cardiac events. Am Heart J. 1996;131:923-9. (Pubitemid 26135755)
23. Germano G, Kiat H, Kavanagh PB, Moriel M, Mazzanti M, Su HT, et al. Automatic quantification of ejection fraction from gated myocardial perfusion SPECT. J Nucl Med. 1995;36:2138-47.
24. Iskandrian AS, Heo J, Lemlek J, Ogilby JD, Untereker WJ, Iskandrian B, et al. Identification of high risk patients with left main and three vessel coronary artery disease by adenosine SPECT thallium imaging. Am Heart J. 1993;125:1130-5. (Pubitemid 23117349)
25. O'Keefe JH Jr, Bateman TM, Ligon RW, Case J, Cullom J, Barnhart C, et al. Outcome of medical versus invasive treatment strategies for non-high-risk ischemic heart disease. J Nucl Cardiol. 1998;5:28-33. (Pubitemid 28084963)
26. He ZX, Cwajg E, Hwang W, Hartley CJ, Funk E, Michael LH, et al. Myocardial blood flow and myocardial uptake of 201-Tl and 99m-Tc-sestamibi during coronary vasodilation induced by CGS- 21680, a selective adenosine A2A receptor agonist. Circulation. 2000;102:438-44. (Pubitemid 30490683)
27. Chow BJW, Wong JW, Yoshinaga K, Ruddy TD, Williams K, deKemp RA, et al. Prognostic significance of dipyridamoleinduced ST depression in patients with normal 82Rb PET myocardial perfusion imaging. J Nucl Med. 2005;46:1095-101. (Pubitemid 43741070)
28. Aksut SV, Mallavarapu C, Russell J, Heo J, Iskandrian AS. Implications of increased lung thallium uptake during exercise single photon emission computed tomography imaging. Am Heart J. 1995;l30:367-73.
29. Moralidis E, Spyridonidis T, Arsos G, Anagnostopoulos C. Identification of advanced coronary with exercise myocardial perfusion imaging: the clinical value of a novel approach for assessing lung thallium-201 uptake. Eur J NuclMed Mol Imaging. 2007;34:573-83. (Pubitemid 46426983)
30. Chae SC, Heo J, Iskandrian AS, Wasserleben V, Cave V. Identification of extensive coronary artery disease in women by exercise single-photon emission computed tomographic (SPECT) thallium imaging. J Am Coll Cardiol. 1993;21:1305-11. (Pubitemid 23138694)
31. Boyne TS, Koplan BA, Parsons WJ, Smith WH, Watson DD, Beller GA. Predicting adverse outcome with exercise SPECT technetium-99m sestamibi imaging in patients with suspected or known coronary artery disease. Am J Cardiol. 1997;79:270-4. (Pubitemid 27093299)
32. Acampa W, Petretta M, Florimonte L, Mattera A, Cuocolo A. Prognostic value of exercise cardiac tomography performed late after percutaneous coronary intervention in symptomatic and symptom-free patients. Am J Cardiol. 2003;91:259-63. (Pubitemid 36143862)
33. Schalet BD, Kegel JG, Heo J, Segal BL, Iskandrian AS. Prognostic implications of normal exercise SPECT Thallium images in patients with strongly positive exercise electrocardiograms. Am J Cardiol. 1993;72:1201-3. (Pubitemid 24050063)
34. Sharir T, Rabinowitz B, Livschitz S, Moalem I, Baron J, Kaplinsky E, et al. Underestimation of extent and severity of coronary artery disease by dipyridamole stress thallium-201 single photon emission computed tomographic myocardial perfusion imaging in patients taking antianginal drugs. J Am Coll Cardiol. 1998;31:1540-6. (Pubitemid 28273296)