Inhibitory effects of acetylmelodorinol, chrysin and polycarpol from mitrella kentii on prostaglandin E2 and thromboxane B2 production and platelet activating factor receptor binding

Molecules

Volumn 17, Issue 5, 2012, Pages 4824-4835

  Saadawi, Sakina ^a   Jalil, Juriyati ^a   Jasamai, Malina ^a   Jantan, Ibrahim ^a  

^a UNIVERSITI KEBANGSAAN MALAYSIA   (Malaysia)

Author keywords

Acetylmelodorinol; Chrysin; Mitrella kentii; Platelet activating factor (PAF) antagonist; Polycarpol; Prostaglandin E 2 (PGE 2); Thromboxane B 2 (TXB 2)

Indexed keywords

ALKENE; CHRYSIN; CYCLOOXYGENASE 1; FIBRINOGEN RECEPTOR; FLAVONOID; G PROTEIN COUPLED RECEPTOR; PLANT EXTRACT; POLYCARPOL; POLYCYCLIC AROMATIC HYDROCARBON; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; THROMBOCYTE ACTIVATING FACTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; THROMBOXANE B2;

ANIMAL; ANNONACEAE; ARTICLE; BIOSYNTHESIS; CHEMISTRY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; IC 50; ISOLATION AND PURIFICATION; METABOLISM; PLANT LEAF; RABBIT; RADIOIMMUNOASSAY; THROMBOCYTE;

ALKENES; ANIMALS; ANNONACEAE; BLOOD PLATELETS; CYCLOOXYGENASE 1; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; HUMANS; INHIBITORY CONCENTRATION 50; PLANT EXTRACTS; PLANT LEAVES; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; POLYCYCLIC HYDROCARBONS, AROMATIC; RABBITS; RADIOIMMUNOASSAY; RECEPTORS, G-PROTEIN-COUPLED; THROMBOXANE B2;

EID: 84861494109     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules17054824     Document Type: Article

References (30)

1. Smith, H.S. Arachidonic acid pathways in nociception. J. Support. Oncol. 2006, 4, 277-287.
2. Arita, H.; Nakano, T.; Hanasaki, K. Thromboxane A2: Its generation and role in platelet activation. Prog. Lipid Res. 1989, 28, 273-301.
3. Gilmer, J.F.; Murphy, M.A.; Shannon, J.A.; Breen, C.G.; Ryder, S.A.; Clancy, J.M. Single oral dose study of two isosorbide-based aspirin prodrugs in the dog. J. Pharm. Pharmacol. 2003, 55, 1351-1357.
4. Dogne, J.M.; Hanson, J.; de Leval, X.; Pratico, D.; Pace-Asciak, C.R.; Drion, P.; Pirotte, B.; Ruan, K.H. From the design to the clinical application of thromboxane modulators. Curr. Pharm. Des. 2006, 12, 903-923.
5. Reed, R.; Holmes, D.; Weyers, J.; Jones, A. Practical Skill in Biomolecular Science, 3th ed.; Pearson Benjamin Cummings: Toronto, ON, Canada, 2007.
6. Stafforini, D.M.; Mclntyre, T.M.; Zimmerman, G.A.; Prescott, S.M. Platelet-activating factor, a pleiotrophic mediator of physiological and pathological processes. Crit. Rev. Clin. Lab. Sci. 2003, 40, 643-672.
7. Petersen, L.J.; Church, M.K.; Skov, P.S. Platelet-activating factor induces histamine release from human skin mast cells in vivo, which is reduced by local nerve blockade. J. Allergy Clin. Immunol. 1997, 99, 640-647.
8. Kasperska-Zajac, A.; Brzoza, Z.; Rogala, B. Platelet-activating factor: A review of its role in asthma and clinical efficacy of PAF antagonists in the disease therapy. Recent Pat. Inflamm. Allergy Drug Discov. 2008, 2, 72-76.
9. Zhang, J.; Li, C.; Guo, X.; Wang, G. Effect of buying huanwu decoction on platelet activating factor content in arterial blood pre- and post-arterial thrombosis in rats. J. Tradit. Chin. Med. 2001, 21, 299-302.
10. Esquenazi, S.; Bazan, H.E. Role of platelet-activating factor in cell death signaling in the cornea: A review. Mol. Neurobiol. 2010, 42, 32-38.
11. Moharam, B.A.; Jantan, I.; Jalil, J.; Shaari, K. Inhibitory Effects of Phylligenin and Quebrachitol Isolated from Mitrephora vulpina on Platelet Activating Factor Receptor Binding and Platelet Aggregation. Molecules 2010, 15, 7840-7848.
12. Schlondorff, D.; Neuwirth, R. Platelet-activating factor and the kidney. Am. J. Physiol. 1986, 251, 1-11.
13. Badr, K.F.; DeBoer, D.K.; Takahasjhi, K.; Harris, R.C.; Fogo, A.; Jacobson, H.R. Glomerular responses to platelet-activating factor in the rat: Role of thromboxane A2. Am. J. Physiol. 1989, 256, 35-43.
14. Arribas-Gomez, I.; Duque-Marin, I.; Perez de Lema, G.; Diez-MarquCs, M.L.; Lucio-Cazaiia, J.; Rodriguez-Puyol, M.; Rodriguez-Puyo, D. A possible role for platelet-activating factor in the hydrogen peroxide-induced TXB2 and PGE2 glomerular synthesis. J. Lipid Res. 1995, 36, 260-265.
15. Wiart, C. Medicinal Plants of the Asia-Pacific: Drugs for the Future? World Scientific Publishing Co. Pte. Ltd: Singapore, 2006.
16. Ellis, J.; Gellert, E.; Summons, R.E. The alkaloids of Mitrella Kentii (Annonaceae). Aust. J. Chem. 1972, 25, 2735-2736.
17. Benosman, A.; Oger, J.M.; Richomme, P.; Bruneton, J. New Terpenylated dihydrochalcone derivatives isolated from Mitrella kentii. J. Nat. Prod. 1997, 60, 921-924.
18. Murphy, B.T. Isolation and Structure Elucidation of Antiproliferative Natural Products from Madagascar; Faculty of Virginia Polytechnic Institute and State University: Blacksburg, VA, USA, 2007.
19. El Antri, A.; Messouri, I.; Tlemçani, R.C.; Bouktaib, M.; El Alami, R.; El Bali, B.; Lachkar, M. Flavone glycosides from Calycotome Villosa subsp. Molecules 2004, 9, 568-573.
20. Jin, S.; Sato, N. Benzoquinone, the substance essential for antibacterial activity in aqueous extracts from succulent young shoots of the pear Pyrus spp. Phytochemistry 2003, 62, 101-107.
21. Ahmed, Y.; Sohrab, H.; Al-Reza, S.M.; Tareq, F.S.; Hasan, C.M.; Sattar, M.A. Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum. Food Chem. Toxicol. 2010, 48, 549-552.
22. Olatunji, L.A.; Soladoye, A.O. Effects of chronic treatment with cyclooxygenase inhibitor, indomethacin on oral contraceptive-induced high blood pressure in female rats. Afr. J. Med. Med. Sci. 2010, 39, 21-27.
23. Shin, J.; Kim, K.; Kim, M.; Jeong, J.; Kim, B. Synthesis and hypoglycemic effect of chrysin derivatives. Bioorg. Med. Chem. Lett. 1999, 9, 869-874.
24. Akihisa, T.; Yasukawa, K. Antitumor-promoting and anti-inflammatory activities of triterpenoids and sterols from plants and fungi. Stud. Nat. Prod. Chem. 2001, 25, 43-87.
25. Gómez, M.A.; Sáenz, M.T.; García, M.D.; Fernández, M.A. Study of the topical anti-inflammatory activity of Achillea ageratum on chronic and acute inflammation models. Z. Naturforsch C. 1999, 54, 937-941.
26. Jantan, I.; Pisar, M.; Sirat, H.M.; Basar, N.; Jamil, S.; Ali, R.M.; Jalil, J. Inhibitory effects of compounds from Zingiberaceae species on platelet activating factor receptor binding. Phytother. Res. 2004, 18, 1005-1007.
27. Koltai, M.; Hosford, D.; Guinot, P.; Esanu, A.; Braquet, P. Platelet activating factor (PAF). A review of its effects, antagonists and possible future clinical implications (Part I). Drugs 1991, 42, 9-29.
28. Ngantchou, I.; Nkwengoua, E.; Nganso, Y.; Nyasse, B.; Denier, C.; Hannaert, V.; Schneider, B. Antitrypanosomal activity of polycarpol from Piptostigma preussi (Annonaceae). Fitoterapia 2009, 80, 188-191.
29. Patrignani, P.; Panara, M.R.; Greco, A.; Fusco, O.; Natoli, C.; Iacobelli, S.; Cipollone, F.; Ganci, A.; Crèminon, C.; Maclouf, J.; Patrono, C. Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J. Pharmacol. Exp. Ther. 1994, 271, 1705-1712.
30. Jantan, I.; Jalil, J.; Abdul Warif, N.M. Platelet-activating factor (PAF) antagonistic activities of compounds isolated from Guttiferae species. Pharm. Biol. 2001, 39, 243-246.