Two-photon microscopy using an Yb3+-doped fiber laser with variable pulse widths

Optics Express

Volumn 20, Issue 11, 2012, Pages 12341-12349

  Kim, Dong Uk ^a   Song, Hoseong ^a   Song, Woosub ^a   Kwon, Hyuk Sang ^a   Sung, Miae ^b   Kim, Dug Young ^b  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Yonsei University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHIRP MODULATION; FIBER LASERS; LASER EXCITATION; MICROSCOPES; MODE-LOCKED FIBER LASERS;

3-DIMENSION; AVERAGE POWER; DORSAL ROOT GANGLIA; FEMTOSECONDS; FREQUENCY CHIRPING; GRATING PAIR; LASER OUTPUT; MICROSCOPE SYSTEMS; MODE-LOCKED; OBJECTIVE LENS; OPTIMUM CONDITIONS; PULSE COMPRESSORS; PULSEWIDTHS; REPETITION RATE; SAMPLE POSITION; TI: SAPPHIRE LASER; TWO PHOTON; TWO PHOTON FLUORESCENCE; TWO PHOTON MICROSCOPY; TWO-PHOTON EXCITATIONS;

PHOTONS;

ARTICLE; EQUIPMENT; EQUIPMENT DESIGN; FIBER OPTICS; FLUORESCENCE MICROSCOPY; IMAGE ENHANCEMENT; INSTRUMENTATION; LASER;

EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; FIBER OPTIC TECHNOLOGY; IMAGE ENHANCEMENT; LASERS; MICROSCOPY, FLUORESCENCE;

EID: 84861491051     PISSN: None     EISSN: 10944087     Source Type: Journal    
DOI: 10.1364/OE.20.012341     Document Type: Article

References (23)

1. W. Denk, J. H. Strickler, and W. W. Webb, "Two-photon laser scanning fluorescence microscopy, " Science 248(4951), 73-76 (1990).
2. A. Diaspro, G. Chirico, F. Federici, F. Cannone, S. Beretta, and M. Robello, "Two-photon microscopy and spectroscopy based on a compact confocal scanning head, " J. Biomed. Opt. 6(3), 300-310 (2001).
3. M. Sridhar, S. Basu, V. L. Scranton, and P. J. Campagnola, "Construction of a laser scanning microscope for multiphoton excited optical fabrication, " Rev. Sci. Instrum. 74(7), 3474-3477 (2003).
4. S. P. Tai, M. C. Chan, T. H. Tsai, S. H. Guol, L. J. Chen, and C. K. Sun; S-, "Two-photon fluorescence microscope with a hollow-core photonic crystal fiber, " Opt. Express 12(25), 6122-6128 (2004).
5. J. J. Mancuso, A. M. Larson, T. G. Wensel, and P. Saggau, "Multiphoton adaptation of a commercial low-cost confocal microscope for live tissue imaging, " J. Biomed. Opt. 14(3), 034048 (2009).
6. H. Yokoyama, H. Guo, T. Yoda, K. Takashima, K. Sato, H. Taniguchi, and H. Ito, "Two-photon bioimaging with picosecond optical pulses from a semiconductor laser, " Opt. Express 14(8), 3467-3471 (2006).
7. K. Taira, T. Hashimoto, and H. Yokoyama, "Two-photon fluorescence imaging with a pulse source based on a 980-nm gain-switched laser diode, " Opt. Express 15(5), 2454-2458 (2007).
8. J. R. Unruh, E. S. Price, R. G. Molla, R. Hui, and C. K. Johnson, "Evaluation of a femtosecond fiber laser for two-photon fluorescence correlation spectroscopy, " Microsc. Res. Tech. 69(11), 891-893 (2006).
9. J. R. Unruh, E. S. Price, R. G. Molla, L. Stehno-Bittel, C. K. Johnson, and R. Hui, "Two-photon microscopy with wavelength switchable fiber laser excitation, " Opt. Express 14(21), 9825-9831 (2006).
10. S. Tang, J. Liu, T. B. Krasieva, Z. Chen, and B. J. Tromberg, "Developing compact multiphoton systems using femtosecond fiber lasers, " J. Biomed. Opt. 14(3), 030508 (2009).
11. E. Büttner, V. Andresen, I. Rimke, and P. Friedl, "Infrared multiphoton microscopy beyond 1 micron: system design and biomedical applications, " Proc. SPIE 6630, 66300H1-66300H-8 (2007)
12. G. Lenz, K. Tamura, H. A. Haus, and E. P. Ippen, "All-solid-state femtosecond source at 155 μm, " Opt. Lett. 20(11), 1289-1291 (1995).
13. A. Chong, W. H. Renninger, and F. W. Wise, "All-normal-dispersion femtosecond fiber laser with pulse energy above 20 nJ, " Opt. Lett. 32(16), 2408-2410 (2007).
14. M. Hofer, M. E. Fermann, F. Haberl, M. H. Ober, and A. J. Schmidt, "Mode locking with cross-phase and self-phase modulation, " Opt. Lett. 16(7), 502-504 (1991).
15. P. Maine, D. Strickland, P. Bado, M. Pessot, and G. Mourou, "Generation of ultrahigh peak power pulses by chirped pulse amplification, " IEEE J. Quantum Electron. 24(2), 398-403 (1988).
16. R. L. Fork, C. H. Cruz, P. C. Becker, and C. V. Shank, "Compression of optical pulses to six femtoseconds by using cubic phase compensation, " Opt. Lett. 12(7), 483-485 (1987).
17. http://www.microscopyu.com/articles/optics/cfintro.html.
18. J. B. Pawley, Handbook of Biological Confocal Microscopy (Springer, 2006), Chap. 9.
19. D. U. Kim, S. Moon, H. Song, H.-S. Kwon, and D. Y. Kim, "Masked illumination scheme for a galvanometer scanning high-speed confocal fluorescence microscope, " Scanning 33(6), 455-462 (2011).
20. A. Diaspro, Confocal and Two-photon Microscopy Foundations, Applications, and Advances (Wiely-Liss, 2002), Chap. 8.
21. G. Koren, "Two-photon photoconductivity phenomena in semiconductors and insulators, " Phys. Rev. B 11(2), 802-821 (1975).
22. J. K. Ranka, A. L. Gaeta, A. Baltuska, M. S. Pshenichnikov, and D. A. Wiersma, "Autocorrelation measurement of 6-fs pulses based on the two-photon-induced photocurrent in a GaAsP photodiode, " Opt. Lett. 22(17), 1344-1346 (1997).
23. F. Träger, Handbook of Lasers and Optics (Springer, 2007), Chap. 12.