Antifertility effect of chronically administered Tabernaemontana divaricata leaf extract on male rats

Asian Pacific Journal of Tropical Medicine

Volumn 5, Issue 7, 2012, Pages 547-551

  Jain, Sachin ^a   Jain, Ankit ^a   Paliwal, Pritesh ^a   Solanki, Shailendra Singh ^a  

^a IPS Academy   (India)

Author keywords

50 ethanol extract; Anti fertility; Hormone levels; Male rats; Reproduction; Tabernaemontana divaricata

Indexed keywords

CONTRACEPTIVE AGENT; FOLLITROPIN; HEMOGLOBIN; PLANT EXTRACT; TABERNAEMONTANA DIVARICATA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CELL MATURATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; EPIDIDYMIS; ERYTHROCYTE COUNT; FOLLITROPIN BLOOD LEVEL; GERM CELL; HEMATOCRIT; HEMOGLOBIN DETERMINATION; MALE; MALE FERTILITY; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; PROSTATE; RAT; REPRODUCTIVE SUCCESS; SEMINAL VESICLE; SEMINIFEROUS TUBULE EPITHELIUM; SERTOLI CELL; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TABERNAEMONTANA; TABERNAEMONTANA DIVARICATA; TESTIS SIZE; TREATMENT DURATION; WEIGHT GAIN;

ANIMALS; BODY WEIGHT; CONTRACEPTIVE AGENTS, MALE; FERTILITY; GONADAL STEROID HORMONES; MALE; ORGAN SIZE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, SPRAGUE-DAWLEY; SEMINAL VESICLES; SEMINIFEROUS TUBULES; SPERM COUNT; SPERM MOTILITY; TABERNAEMONTANA; TESTIS;

EID: 84861489953     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(12)60096-0     Document Type: Article

References (16)

1. Benzophenous Arvind Naphthophenones and related compounds as spermicidal agents. Indian J Pharm Sci 1994, 56(3):105-108.
2. Bagul MS, Niranjan SK, Rajani M Evaluation of free radical scavenging properties of two classical polyherbal formulations. Indian J Exp Biol 2005, 43:732-736.
3. Chatterjee A, Pakrashi SC The treatise on Indian medicinal plants 1995, Vol II. Publication and Information Directorate, New Delhi.
4. Chase DJ, Karle JA, Fogg RE Maintenance or stimulation of steroidogenic enzymes and testosterone production in rat Leydig cell by continuous and pulsatile infusions of luteinizing harmone during passive immunization against gonadrotrophin releasing harmone. J Reprod Fertil 1992, 95:657-667.
5. Cooper TG The epididymis as a site of contraceptive attack. Spermatogenesis, fertilization, contraception 1992, 419-460. Springer, Berlin. E. Nieschlag, U.F. Habenicbt (Eds.).
6. Evans WC Pharmacognosy 2001, 247. WB Saunders Company Ltd, London. 15th ed.
7. Ewing LL, Davis JC, Zirkin BR Regulating testicular fungtion: a special and temporal view. Int Rev Physiol 1980, 22:41-115.
8. Jagadish VK, Rana AC Preliminary study on antifertility activity of Calotropis procera roots in female rats. Fitoterapia 2002, 73:111-115.
9. Lohiya NK, Goyal RB, Jayaprakash D, Sharma S, Kumar M, Ansari AS Introduction of reversible antifertility with a crude ethanol extract of Carica papaya seed in albino male rats. Int J Pharmacog 1992, 30:308-320.
10. Mali PC, Ansari AS, Chaturvedi M Antifertility effect of chronically administered Martynia annua root extract on male rats. J Ethnopharmacol 2002, 82:61-67.
11. Orgebin-Crist MC, Hoffman LH, Olson GE, Skudlarek MD Secretion of protein and glycoprotein by perifused rabbit corpus epididymal tubules and effect of castration. Am J Anat 1987, 180:49-55.
12. Prasad MRN, Chinoy NJ, Kadam KM Changes in sussinate dehydrogenate levels in rat epididymis under normal and altered physiological conditions. Fertil Sterl 1972, 23:186-190.
13. Shan LX, Hardy MP Developmental changes in level of luteinizing harmone receptor and androgen receptor in in rat Leydig cells. Endocrinology 1992, 131:1107-1114.
14. Toney TW, Danzo BJ Estrogen and androgen regulation of protein synthesis by the immature rat epididymis. Endocrinology 1989, 125:231-242.
15. Verhoeven G Local control system within the testis. In: Tindall B. (ed.). Baillier's Clin Endocrinol Metab 1992, 6(2):313-333.
16. Warrier PK, Nambiar VPK, Ramankutty C Indian medicinal plants 1996, Vol II. Orient Longman Ltd, Madras.