Assessment of atherosclerotic plaques in a rabbit model by delayed-phase contrast-enhanced CT angiography: Comparison with histopathology

International Journal of Cardiovascular Imaging

Volumn 28, Issue 2, 2012, Pages 353-363

  Hur, Jin ^a   Kim, Young Jin ^a   Shim, Hyo Sup ^b   Lee, Hye Jeong ^a   Nam, Ji Eun ^a   Choe, Kyu Ok ^a   Choi, Byoung Wook ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

Author keywords

Atherosclerotic plaque; Composition; Computed tomography angiography (CTA)

Indexed keywords

ABDOMINAL AORTA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; COMPUTED TOMOGRAPHIC ANGIOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DELAYED DIAGNOSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC TEST ACCURACY STUDY; DIFFERENTIAL DIAGNOSIS; EARLY DIAGNOSIS; EXPERIMENTAL RABBIT; HISTOPATHOLOGY; IMAGE ANALYSIS; IMAGE QUALITY; INTERMETHOD COMPARISON; MALE; NONHUMAN; SENSITIVITY AND SPECIFICITY;

ANIMALS; AORTA, ABDOMINAL; AORTIC DISEASES; AORTOGRAPHY; ATHEROSCLEROSIS; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; FIBROSIS; LIPIDS; MACROPHAGES; MALE; PLAQUE, ATHEROSCLEROTIC; PREDICTIVE VALUE OF TESTS; RABBITS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84861481385     PISSN: 15695794     EISSN: 15730743     Source Type: Journal    
DOI: 10.1007/s10554-011-9801-x     Document Type: Article

References (30)

1. Waxman S (1999) Characterization of the unstable lesion by angiography, angioscopy, and intravascular ultrasound. Cardiol Clin 17:295-305
2. Virmani R, Burke AP, Kolodgie FD, Farb A (2002) Vulnerable plaque: the pathology of unstable coronary lesions. J Interv Cardiol 15:439-446 (Pubitemid 35387383)
3. Kolodgie FD, Burke AP, Farb A et al (2001) The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes. Curr Opin Cardiol 16:285-292 (Pubitemid 32953605)
4. Goldstein JA, Demetriou D, Grines CL, Pica M, Shoukfeh M, O'Neill WW (2000) Multiple complex coronary plaques in patients with acute myocardial infarction. N Engl J Med 343:915-922
5. Newby AC, Libby P, van der Wal AC (1999) Plaque instability - the real challenge for atherosclerosis research in the next decade? Cardiovasc Res 41:321-322 (Pubitemid 29087328)
6. Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM (2000) Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20:1262-1275 (Pubitemid 30262927)
7. Fayad ZA, Fuster V (2001) Clinical imaging of the high-risk or vulnerable atherosclerotic plaque. Circ Res 89:305-316 (Pubitemid 34132668)
8. Caussin C, Ohanessian A, Ghostine S et al (2004) Characterization of vulnerable nonstenotic plaque with 16-slice computed tomography compared with intravascular ultrasound. Am J Cardiol 94:99-104 (Pubitemid 38813461)
9. Schroeder S, Kopp AF, Baumbach A et al (2001) Noninvasive detection and evaluation of atherosclerotic coronary plaques with multislice computed tomography. J Am Coll Cardiol 37:1430-1435
10. Leber AW, Knez A, Becker A et al (2004) Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques: a comparative study with intracoronary ultrasound. J Am Coll Cardiol 43:1241-1247 (Pubitemid 38452602)
11. Pohle K, Achenbach S, Macneill B et al (2007) Characterization of non-calcified coronary atherosclerotic plaque by multi-detector row CT: comparison to IVUS. Atherosclerosis 190:174-180 (Pubitemid 44908312)
12. Schroeder S, Flohr T, Kopp AF et al (2001) Accuracy of density measurements within plaques located in artificial coronary arteries by X-ray multislice CT: results of a phantom study. J Comput Assist Tomogr 25:900-906 (Pubitemid 33091668)
13. Yuan C, Kerwin WS, Ferguson MS et al (2002) Contrast-enhanced high resolution MRI for atherosclerotic carotid artery tissue characterization. J Magn Reson Imaging 15:52-67
14. Wasserman BA, Smith WI, Trout HH, Cannon RO, Balaban RS, Arai AE (2002) Carotid artery atherosclerosis: in vivo morphologic characterization with gadolinium enhanced double-oblique MR imaging - initial results. Radiology 223:566-573 (Pubitemid 34454344)
15. Cademartiri F, Mollet NR, Runza G et al (2005) Influence of intracoronary attenuation on coronary plaque measurements using multislice computed tomography: observations in an ex vivo model of coronary computed tomography angiography. Eur Radiol 15:1426-1431 (Pubitemid 40983527)
16. Halliburton SS, Schoenhagen P, Nair A et al (2006) Contrast enhancement of coronary atherosclerotic plaque: a high-resolution, multidetector-row computed tomography study of pressure-perfused, human ex vivo coronary arteries. Coron Artery Dis 17:553-560 (Pubitemid 44231684)
17. Nikolaou K, Flohr T, Knez A et al (2004) Advances in cardiac CT imaging: 64-slice scanner. Int J Cardiovasc Imaging 20:535-540 (Pubitemid 40372368)
18. Raff GL, Gallagher MJ, O'Neill WW, Goldstei JA (2005) Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol 46:552-557 (Pubitemid 41040301)
19. Nikolaou K, Becker CR, Flohr T et al (2004) Optimization of ex vivo CT- and MR-imaging of atherosclerotic vessel wall changes. Int J Cardiovasc Imaging 20:327-334
20. Libby P (2002) Inflammation in atherosclerosis. Nature 420:868-874
21. van der Wal AC, Becker AE, van der Loos CM, Das PK (1994) Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology. Circulation 89:36-44
22. Hansson GK (2005) Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352:1685-1695
23. Calcagno C, Cornily JC, Hyafil F et al (2008) Detection of neovessels in atherosclerotic plaques of rabbits using dynamic contrast enhanced MRI and 18F-FDG PET. Arterioscler Thromb Vasc Biol 28:1311-1317
24. Moselewski F, Ropers D, Pohle K et al (2004) Comparison of measurement of cross-sectional coronary atherosclerotic plaque and vessel areas by 16-slice multidetector computed tomography versus intravascular ultrasound. Am J Cardiol 94:1294-1297 (Pubitemid 39469953)
25. Leber AW, Knez A, von Ziegler F et al (2005) Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography; a comparative study with quantitative coronary angiography and intravascular ultrasound. J Am Coll Cardiol 46:147-154 (Pubitemid 40905143)
26. Leber AW, Becker A, Knez A et al (2006) Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system; a comparative study using intravascular ultrasound. J Am Coll Cardiol 47:672-677 (Pubitemid 43170862)
27. Chopard R, Boussel L, Motreff P et al (2010) How reliable are 40 MHz IVUS and 64-slice MDCT in characterizing coronary plaque composition? An ex vivo study with histopathological comparison. Int J Cardiovasc Imaging 26:373-383
28. Viles-Gonzalez JF, Poon M, Sanz J et al (2004) In vivo 16-slice, multidetectorrow computed tomography for the assessment of experimental atherosclerosis: comparison with magnetic resonance imaging and histopathology. Circulation 110:1467-1472 (Pubitemid 39238025)
29. McMahon AC, Kritharides L, Lowe HC (2005) Animal models of atherosclerosis progression: current concepts. Curr Drug Targets Cardiovasc Haematol Disord 5:433-440 (Pubitemid 43008517)
30. Bengel FM (2006) Atherosclerosis imaging on the molecular level. J Nucl Cardiol 13:111-118