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Volumn 9, Issue 6, 2012, Pages 315-316

Pharmacogenetics: Point-of-care genetic testing - A new frontier explored

Author keywords

[No Author keywords available]

Indexed keywords

CLOPIDOGREL; CYTOCHROME P450 2C19;

EID: 84861479130     PISSN: 17595002     EISSN: 17595010     Source Type: Journal    
DOI: 10.1038/nrcardio.2012.63     Document Type: Short Survey
Times cited : (5)

References (10)
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    • Roberts, J. D. et al. Point-of-care genetic testing for personalisation of antiplatelet treatment (RAPID GENE): a prospective, randomised, proof-of-concept trial. Lancet http://dx.doi.org/ 10.1016/S0140-6736(12)60161-5.
    • Lancet
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  • 2
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    • Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
    • Mega, J. L. et al. Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA 304, 1821-1830 (2010).
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    • Mega, J.L.1
  • 3
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    • Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation
    • Price, M. J. et al. Prognostic significance of post-clopidogrel platelet reactivity assessed by a point-of-care assay on thrombotic events after drug-eluting stent implantation. Eur. Heart J. 29, 992-1000 (2008).
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    • Price, M.J.1
  • 4
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    • Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation
    • Breet, N. J. et al. Comparison of platelet function tests in predicting clinical outcome in patients undergoing coronary stent implantation. JAMA 303, 754-762 (2010).
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    • Breet, N.J.1
  • 5
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    • Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate
    • Bonello, L. et al. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. J. Am. Coll. Cardiol. 56, 919-933 (2010).
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    • Bonello, L.1
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    • Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: A time-dependent analysis of the Gauging Responsiveness with a VerifyNow P2Y12 assay: Impact on Thrombosis and Safety (GRAVITAS) trial
    • Price, M. J. et al. Platelet reactivity and cardiovascular outcomes after percutaneous coronary intervention: a time-dependent analysis of the Gauging Responsiveness with a VerifyNow P2Y12 assay: Impact on Thrombosis and Safety (GRAVITAS) trial. Circulation 124, 1132-1137 (2011).
    • (2011) Circulation , vol.124 , pp. 1132-1137
    • Price, M.J.1
  • 7
    • 84555195438 scopus 로고    scopus 로고
    • CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: A systematic review and meta-analysis
    • Holmes, M. V., Perel, P., Shah, T., Hingorani, A. D. & Casas, J. P. CYP2C19 genotype, clopidogrel metabolism, platelet function, and cardiovascular events: a systematic review and meta-analysis. JAMA 306, 2704-2714 (2011).
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    • Patay, B. A. & Topol, E. J. The unmet need of education in genomic medicine. Am. J. Med. 125, 5-6 (2012).
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.