The flavonoid resveratrol suppresses growth of human malignant pleural mesothelioma cells through direct inhibition of specificity protein 1

International Journal of Molecular Medicine

Volumn 30, Issue 1, 2012, Pages 21-27

  Lee, Kyung Ae ^a   Lee, Yong Jin ^a   Ban, Jung Ok ^b   Lee, Yoon Jin ^a   Lee, Sang Han ^a   Cho, Moon Kyun ^a   Nam, Hae Seon ^a   Hong, Jin Tae ^b   Shim, Jung Hyun ^a  

^a Soonchunhyang University   (South Korea)

^b Chungbuk National University   (South Korea)

Author keywords

Antitumor effect; Apoptosis; Human malignant pleural mesothelioma; Resveratrol; Specificity protein 1

Indexed keywords

BIM PROTEIN; CASPASE 3; CYCLIN D1; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL XL; PROTEIN BID; PROTEIN MCL 1; PROTEIN P21; PROTEIN P27; RESVERATROL; SURVIVIN; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL DEATH; CELL SUBPOPULATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; IC 50; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PLEURA MESOTHELIOMA; PRIORITY JOURNAL; PROTEIN INTERACTION; UPREGULATION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CELL LINE, TUMOR; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MEMBRANE PROTEINS; MESOTHELIOMA; MICE; MICE, INBRED BALB C; MICE, NUDE; PLEURAL NEOPLASMS; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA, MESSENGER; SP1 TRANSCRIPTION FACTOR; STILBENES; TRANSPLANTATION, HETEROLOGOUS;

EID: 84861476091     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2012.978     Document Type: Article

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