In Vivo experiments and numerical investigations on nanocryosurgical freezing of target tissues with large blood vessels

Journal of Biomedical Nanotechnology

Volumn 8, Issue 1, 2012, Pages 10-18

  Sun, Zi Qiao ^a   Yang, Yang ^a   Liu, Jing ^a,b  

^a TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY   (China)

^b Tsinghua University ^*  (China)

Author keywords

Bioheat transfer; In Vivo experiment; Large blood vessel; Nano medicine; Nano Cryosurgery; Phase change

Indexed keywords

BIO-HEAT TRANSFER; IN-VIVO EXPERIMENTS; NANO-CRYOSURGERY; NANOMEDICINES; PHASE CHANGE;

CRYOSURGERY; EXPERIMENTS; FREEZING; HISTOLOGY; NANOPARTICLES; THREE DIMENSIONAL COMPUTER GRAPHICS; TUMORS;

BLOOD VESSELS;

NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD FLOW; CANCER TISSUE; CRYOSURGERY; FEMORAL ARTERY; FREEZING; GREAT BLOOD VESSEL; HEAT TRANSFER; IN VIVO STUDY; MATHEMATICAL COMPUTING; NANOCRYOSURGERY; NONHUMAN; PREDICTION; RABBIT; SIMULATION; TARGET ORGAN; THERMAL CONDUCTIVITY;

ANIMALS; COMPUTER SIMULATION; CRYOSURGERY; FEMALE; FEMORAL ARTERY; HINDLIMB; MAGNETITE NANOPARTICLES; NANOMEDICINE; RABBITS; THERMODYNAMICS; THERMOGRAPHY;

EID: 84861474801     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1362     Document Type: Article

References (38)

1. B. Rubinsky, Cryosurgery. Annu. Rev. Biomed. Eng. 2, 157 (2000).
2. J. C. Bischof, Quantitative measurement and prediction of biophysical response during freezing in tissues. Annu. Rev. Biomed. Eng. 2, 257 (2000).
3. A. A. Gage and J. G. Baust, Mechanisms of tissue injury in cryosurgery. Cryobiology 37, 171 (1998).
4. X. L. Chen, Y. Ma, Y. Wan, and L. G. Duan, Experimental study of the safety of pancreas cryosurgery the comparison of 2 different techniques of cryosurgery. Pancreas 39, 92 (2010).
5. C. W. Kessinger, C. Khemtong, O. Togao, M. Takahashi, B. D. Sumer, and J. Gao, In vivo angiogenesis imaging of solid tumors by alpha(v)beta(3)-targeted, dual-modality micellar nanoprobes. Exp. Biol. Med. 235, 957 (2010).
6. M. Welter, K. Bartha, and H. Rieger, Vascular remodelling of an arterio-venous blood vessel network during solid tumour growth. J. Theor. Biol. 259, 405 (2009).
7. Y. T. Zhang, J. Liu, and Y. X. Zhou, Pilot study on cryogenic heat transfer in biological tissues embedded with large blood vessels. Forsch. Ingenieurwes 67, 188 (2002).
8. J. Crezee and J. J. W. Lagendijk, Temperature uniformity during hyperthermia - The impact of large vessels. Phys. Med. Biol. 37, 1321 (1992).
9. A. Ogulu, Effect of heat generation on low Reynolds number fluid and mass transport in a single lymphatic blood vessel with uniform magnetic field. Int. Commun. Heat. Mass. 33, 790 (2006).
10. H. P. Wu, A. A. Exner, T. M. Krupka, B. D. Weinberg, and J. R. Haaga, Vasomodulation of tumor blood flow: Effect on perfusion and thermal ablation size, Ann. Biomed. Eng. 37, 552 (2009).
11. S. K. Calderwood and J. A. Dickson, Effect of high blood-sugar levels on blood-flow and thermal responses of animal tumors. Brit. J. Cancer 42, 181 (1980).
12. R. J. Rawnsley, R. B. Roemer and A. W. Dutton, The simulation of discrete vessel effects in experimental hyperthermia. ASME J. Biomech. Eng. 116, 256 (1994).
13. C. Kim, A. P. O'Rourke, J. A. Will, D. M. Mahvi, and J. G. Webster, Finite-element analysis of hepatic cryoablation around a large blood vessel. IEEE. Trans. Bio-Med. Eng. 55, 2087 (2008).
14. B. Paliwal, P. D. Higgins, E. L. Madsen, J. A. Zagzebski, M. Seaburg, and R. A. Steeves, Simulation of perfusion and large vessel blood-flow in hyperthermia. Int. J. Radiat. Oncol. 8, 1840 (1982).
15. Z. P. Chen and R. B. Roemer, The effects of large blood-vessels on temperature distributions during simulated hyperthermia. ASME J. Biomech. Eng. 114, 473 (1992).
16. O. I. Craciunescu and S. T. Clegg, Pulsatile blood flow effects on temperature distribution and heat transfer in rigid vessels. ASME J. Biomech. Eng. 123, 500 (2001).
17. Q. H. He, L. Zhu, and S. Weinbaum, Effect of blood flow on thermal equilibration and venous rewarming. Ann. Biomed. Eng. 31, 659 (2003).
18. J. C. Chato, Heat-transfer to blood-vessels. ASME J. Biomech. Eng. 102, 110 (1980).
19. J. K. Seifert and D. L. Morris, Indicators of recurrence following cryotherapy for hepatic metastases from colorectal cancer. Brit. J. Surg. 86, 234 (1999).
20. T. Mala, L. Frich, L. Aurdal, O. P. Clausen, B. Edwin, O. Soreide, and I. P. Gladhaug, hepatic vascular inflow occlusion enhances tissue destruction during cryoablation of porcine liver. J. Surg. Res. 115, 265 (2003).
21. Z. S. Deng, J. Liu, and H. W. Wang, Disclosure of the significant thermal effects of large blood vessels during cryosurgery through infrared temperature mapping. Int. J. Therm. Sci. 47, 530 (2008).
22. J. Liu, Principle of Cryobiomedical Engineering, Science Press, Beijing (2004).
23. A. Shitzer, Cryosurgery: Analysis and experimentation of cryoprobes in phase changing media. ASME J. Heat 133, 011005 (2011).
24. A. A. Gage, J. M. Baust, and J. G. Baust, Experimental cryosurgery investigations in vivo. Cryobiology 59, 229 (2009).
25. D. Chiu, L. Z. Niu, F. Mu, X. Peng, L. Zhou, H. B. Li, R. Li, J. Ni, N. Jiang, Y. Hu, Z. Hao, and K. Xu, The experimental study for efficacy and safety of pancreatic cryosurgery. Cryobiology 60, 281 (2010).
26. T. H. Yu, J. Liu, and Y. X. Zhou, Selective freezing of target biological tissues after injection of solutions with specific thermal properties. Cryobiology 50, 174 (2005).
27. Z. S. Deng and J. Liu, Numerical simulation of selective freezing of target biological tissues following injection of solutions with specific thermal properties. Cryobiology 50, 183 (2005).
28. Z. S. Deng and J. Liu, Numerical study of the effects of large blood vessels on three-dimensional tissue temperature profiles during cryosurgery. Numer. Heat. Trans. A-Appl. 49, 47 (2006).
29. G. Beckerman, A. Shitzer, and D. Degani, Numerical simulation of the effects of a thermally significant blood vessel on freezing by a circular surface cryosurgical probe compared with experimental data. ASME J. Heat. Trans. 131, 051101 (2009).
30. J. Liu, J. F. Yan, and Z. S. Deng, Nano-cryosurgery: A basic way to enhance freezing treatment of tumor, Proceedings of IMECE2007-43916 ASME International Mechanical Engineering Congress and Exposition, Seattle, Washington, USA, November (2007).
31. J. F. Yan and J. Liu, Nanocryosurgery and its mechanisms for enhancing freezing efficiency of tumor tissues. Nanomedicine: Nanotechnology, Biology, and Medicine 4, 79 (2008).
32. Z. S. Deng, J. Liu, J. F. Yan, Z. Q. Sun, and Y. X. Zhou, Experimental and numerical investigation on simulating nano-cryosurgery of target tissues embedded with large blood vessels. Advances in Numerical Heat Transfer, edited by W. J. Minkowycz, E. M. Sparrow, and J. P. Abraham, Taylor & Francis, Washingtan DC (2009), Vol. 3, pp. 221-256.
33. J. Liu, Y. X. Zhou, T. Yu, L. Gui, Z. S. Deng, and Y. G. Lv, Minimally invasive probe system capable of performing both cryosurgery and hyperthermia treatment on target tumor in deep tissues. Minim. Invasiv. Ther. 13, 47 (2004).
34. H. H. Pennes, Analysis of tissue and arterial blood temperatures in the resting human forearm. J. Appl. Physiol. 1, 93 (1948).
35. Z. Q. Sun, Y. X. Zhou, and J. Liu, Concentration effects of nanoparticles on enhancing nanocryosurgery, Proceedings of The 2nd IEEE International Conference on Nano/Molecular Medicine and Engineering, Suzhou, China, November (2008).
36. H. Hao and Y. F. Chen, Atomistic simulations of the load dependant friction force between silicon tip and diamond substrate. J. Nanosci. Nanotechnol. 10, 7501 (2010).
37. Y. Li and L. Gu, Computer simulation of the inclusion of hydrophobic nanoparticles into a lipid bilayer. J. Nanosci. Nanotechnol. 10, 7616 (2010).
38. J. H. Ryu, H. Y. Kim, D. H. Kim, S. K. Choi, and H. M. Lee, Segregation and tnternal structures in the bimetallic clusters: Density functional theory and molecular dynamics simulation. J. Nanosci. Nanotechnol. 9, 2553 (2009).