Fenugreek with reduced bitterness prevents diet-induced metabolic disorders in rats

Lipids in Health and Disease

Volumn 11, Issue , 2012, Pages

  Muraki, Etsuko ^a   Chiba, Hiroshige ^a   Taketani, Keiko ^b   Hoshino, Shohei ^b   Tsuge, Nobuaki ^b   Tsunoda, Nobuyo ^a   Kasono, Keizo ^a  

^a JOSAI UNIVERSITY   (Japan)

^b House Foods Corporation   (Japan)

Author keywords

Diet induced metabolic disorders; FRB; High fat high sucrose diet; Rats

Indexed keywords

BETA GLUCOSIDASE; CHOLESTEROL; FAT; FECES LIPID; FENUGREEK EXTRACT; GLUCOSE; LIPID; PLANT EXTRACT; SUCROSE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BITTER TASTE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIET; DYSLIPIDEMIA; FABALES; FATTY LIVER; FENUGREEK; FOOD INTAKE; GLUCOSE METABOLISM; INSULIN RESISTANCE; KIDNEY; LIPID LIVER LEVEL; LIPID METABOLISM; LIVER; MALE; METABOLIC DISORDER; MUSCLE MASS; NONHUMAN; RAT; SOLEUS MUSCLE; WEIGHT GAIN; WHITE ADIPOSE TISSUE;

ANIMALS; DIET, HIGH-FAT; EATING; LIPID METABOLISM; MALE; METABOLIC DISEASES; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; TRIGONELLA;

RATTUS; TRIGONELLA FOENUM-GRAECUM;

EID: 84861473911     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/1476-511X-11-58     Document Type: Article

References (27)

1. Fenugreek (Trigonella foenum-graecum): A review of health beneficial physiological effects. Srinivasan K, Food Rev Int 2006 22 203 224 10.1080/87559120600586315
2. Dietary fenugreek seed regresses preestablished cholesterol gallstones in mice. Reddy RL, Srinivasan K, Can J Physiol Pharmacol 2009 87 684 693 10.1139/Y09-062 19794519
3. Fenugreek seeds reduce atherogenic diet-induced cholesterol gallstone formation in experimental mice. Reddy RL, Srinivasan K, Can J Physiol Pharmacol 2009 87 933 943 10.1139/Y09-084 19935901
4. Trigonellafoenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reversing the altered glycolytic, gluconeogenic and lipogenic enzymes. Raju J, Gupta D, Rao AR, Yadava PK, Baquer NZ, Mol Cell Biochem 2001 224 45 51 10.1023/A:1011974630828 11693199
5. Lower doses of vanadate in combination with trigonella restore altered carbohydrate metabolism and antioxidant status in alloxan-diabetic rats. Mohamad S, Taha A, Bamezai RN, Basir SF, Baquer NZ, Clin Chim Acta 2004 342 105 114 10.1016/j.cccn.2003.12.005 15026271
6. Biochemical study of the anti-diabetic action of the Egyptian plants Fenugreek and Balanites. Gad MZ, El-Sawalhi MM, Ismail MF, El-Tanbouly ND, Mol Cell Biochem 2006 281 173 183 10.1007/s11010-006-0996-4 16328970
7. 4-Hydroxyisoleucine: experimental evidence of its insulinotropic and antidiabetic properties. Broca C, Gross R, Petit P, Sauvaire Y, Manteghetti M, Tournier M, Masiello P, Gomis R, Ribes G, Am J Physiol 1999 277 617 E623 10516120
8. 4-Hydroxyisoleucine: a plant-derived treatment for metabolic syndrome. Jette L, Harvey L, Eugeni K, Levens N, Curr Opin Investig Drugs 2009 10 353 358 19337956
9. In vitro intestinal glucose uptake is inhibited by galactomannan from Canadian fenugreek seed (Trigonella foenum graecum L) in genetically lean and obese rats. Srichamroen A, Thomson AB, Field CJ, Basu TK, Nutr Res 2009 29 49 54 10.1016/j.nutres.2008.11.002 19185777
10. The modifying effects of galactomannan from Canadian-grown fenugreek (Trigonella foenum-graecum L.) on the glycemic and lipidemic status in rats. Srichamroen A, Field CJ, Thomson AB, Basu TK, J Clin Biochem Nutr 2008 43 167 174 10.3164/jcbn.2008060 19015751
11. Fenugreek improves diet-induced metabolic disorders in rats. Muraki E, Chiba H, Tsunoda N, Kasono K, Horm Metab Res 2011 43 950 955 22113420
12. Dose-dependent effects, safety and tolerability of fenugreek in diet-induced metabolic disorders in rats. Muraki E, Hayashi Y, Chiba H, Tsunoda N, Kasono K, Lipids Health Dis 2011 10 240 10.1186/1476-511X-10-240 22188728
13. Regarding bitter components in fenugreek (Trigonella foenum-graecum L.) seeds. Masamura N, Sawada H, Abstract of the 14 th Annual Meeting of Japan Society for Spice Research (Nihon Koshinryo Kenkyukai koen yoshisu) 1999 22 23 cf. Preparing additional file
14. Diosgenin present in fenugreek improves glucose metabolism by promoting adipocyte differentiation and inhibiting inflammation in adipose tissues. Uemura T, Hirai S, Mizoguchi N, Goto T, Lee JY, Taketani K, Nakano Y, Shono J, Hoshino S, Tsuge N, Narukami T, Takahashi N, Kawada T, Mol Nutr Food Res 2010 54 1596 1608 10.1002/mnfr.200900609 20540147
15. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. Reeves PG, Nielsen FH, Fahey GC, J Nutr 1993 123 1939 1951 8229312
16. Determination of soluble and insoluble dietary fiber in psyllium-containing cereal products. Lee SC, Rodriguez F, Storey M, Farmakalidis E, Prosky L, J AOAC Int 1995 78 724 729 7756888
17. A rapid method of total lipid extraction and purification. Bligh EG, Dyer WJ, Can J Biochem Physiol 1959 37 911 917 10.1139/o59-099 13671378
18. A simple method for the isolation and purification of total lipides from animal tissues. Folch J, Lees M, Sloane Stanley GH, J Biol Chem 1957 226 497 509 13428781
19. Ten different dietary fibers have significantly different effects on serum and liver lipids of cholesterol-fed rats. Anderson JW, Jones AE, Riddell-Mason S, J Nutr 1994 124 78 83 8283297
20. Colonic health: fermentation and short chain fatty acids. Wong JM, de Souza R, Kendall CW, Emam A, Jenkins DJ, J Clin Gastroenterol 2006 40 235 243 10.1097/00004836-200603000-00015 16633129
21. The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype. Comalada M, Bailán E, de Haro O, Lara-Villoslada F, Xaus J, Zarzuelo A, Gálvez JM, J Cancer Res Clin Oncol 2006 132 487 497 10.1007/s00432-006-0092-x 16788843
22. In vitro fermentation of various food fiber fractions. Casterline JL, Oles CJ, Ku Y, J Agr Food Chem 1997 45 2463 2467 10.1021/jf960846f
23. Major determinants of plasma glucose-flattening activity of a water-soluble dietary fiber: Effects of konjac mannan on gastric emptying and intraluminal glucose-diffusion. Ebihara K, Masuhara R, Kiriyama S, Nutr Rep Int 1981 23 1145 1156
24. Diosgenin attenuates inflammatory changes in the interaction between adipocytes and macrophages. Hirai S, Uemura T, Mizoguchi N, Lee JY, Taketani K, Nakano Y, Hoshino S, Tsuge N, Narukami T, Yu R, Takahashi N, Kawada T, Mol Nutr Food Res 2010 54 797 804 19998383
25. Anti-metabolic syndrome and immunostimulant activities of Egyptian fenugreek seeds in diabetic/obese and immunosuppressive rat models. Ramadan G, El-Beih NM, Abd El-Kareem HF, Br J Nutr 2010 23 1 10
26. Effect of dietary fenugreek seeds on biliary proteins which influence nucleation of cholesterol crystals in bile. Reddy RR, Srinivasan K, Steroids 2011 76 455 463 10.1016/j.steroids.2010.12.015 21215764
27. Diosgenin, the main aglycon of fenugreek, inhibits LXR activity in HepG2 cells and decreases plasma and hepatic triglycerides in obese diabetic mice. Uemura T, Goto T, Kang MS, Mizoguchi N, Hirai S, Lee JY, Nakano Y, Shono J, Hoshino S, Taketani K, Tsuge N, Narukami T, Makishima M, Takahashi N, Kawada T, J Nutr 2011 141 17 23 10.3945/jn.110.125591 21106928