Acute toxicity study of cisplatin loaded long-circulating and pH-sensitive liposomes administered in mice

Journal of Biomedical Nanotechnology

Volumn 8, Issue 2, 2012, Pages 229-239

  Leite, Elaine A ^a,b   Lana, Ângela M Q ^a   Carvalho, Álvaro D ^a,b   Coelho, Luiz G V ^a   De Oliveira, Mônica C ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b UNIVERSIDADE FEDERAL DOS VALES DO JEQUITINHONHA E MUCURI   (Brazil)

Author keywords

Cancer; Cisplatin; Intravenous administration; Liposomes; Toxicity

Indexed keywords

ANTHROPOMETRY; BLOOD; CREATININE; LIPOSOMES; MAMMALS; PH SENSORS; UREA;

ACUTE TOXICITY; BODY WEIGHT; CANCER; CIS-PLATIN; CISPLATIN; INTRAVENOUS ADMINISTRATION; LONG CIRCULATING; MAXIMUM TOLERATED DOSE; NEPHROTOXICITY; PH-SENSITIVE LIPOSOMES;

TOXICITY;

CISPLATIN; LIPOSOME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW TOXICITY; CONTROLLED STUDY; DRUG DOSAGE FORM COMPARISON; DRUG DOSE COMPARISON; FEMALE; HISTOPATHOLOGY; LD 50; LIPOSOMAL DELIVERY; LIVER TOXICITY; MALE; MAXIMUM TOLERATED DOSE; MORTALITY; MOUSE; NEPHROTOXICITY; NONHUMAN; WEIGHT CHANGE;

EID: 84861471008     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1388     Document Type: Article

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