A comparative study of loratadine syrup and cyproheptadine HCL solution for treating perennial allergic rhinitis in taiwanese children aged 2-12 years

International Journal of Immunopathology and Pharmacology

Volumn 25, Issue 1, 2012, Pages 231-237

  Wu, Keh Gong ^a   Li, T H ^a,b   Wang, T Y ^a   Hsu, C L ^a   Chen, C J ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b HUALIEN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

Children; Cyproheptadine; Loratadine; Perennial allergic rhinitis; Visual analogue scales

Indexed keywords

CYPROH; CYPROHEPTADINE; LORATADINE; UNCLASSIFIED DRUG;

ARTICLE; BODY HEIGHT; BODY WEIGHT; CHILD; CONTROLLED STUDY; DRUG EFFICACY; DRUG SOLUTION; FEMALE; GROUPS BY AGE AND SEX; HUMAN; MAJOR CLINICAL STUDY; MALE; MITE; NASAL PRURITUS; PERENNIAL RHINITIS; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; STATISTICAL SIGNIFICANCE; SYMPTOMATOLOGY; SYRUP; TAIWAN; VISUAL ANALOG SCALE; AGE; CLINICAL EVALUATION; COMPARATIVE STUDY; DROWSINESS; DRUG EFFECT; DRUG SAFETY; EPIPHORA; EYE PAIN; EYE REDNESS; FOLLOW UP; GENDER; INCREASED APPETITE; MOUTH BREATHING; NOSE OBSTRUCTION; OCULAR PRURITUS; OPEN STUDY; OUTCOME ASSESSMENT; PRURITUS; RHINORRHEA; SNEEZING; SNIFFING; SYMPTOM; TAIWANESE; TREATMENT OUTCOME; VISUAL DISORDER;

EID: 84861462648     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201202500125     Document Type: Article

References (26)

1. Skoner DP. Allergic rhinitis: definition, epidemiology, pathophysiology, detection, and diagnosis. J Allergy Clin Immunol 2001; 108:2-8.
2. Lee YL, Shaw CK, Su HJ, Lai JS, Ko YC, Huang SL, Sung FC, Guo YL. Climate, traffic-related air pollutants and allergic rhinitis prevalence in middle-school children in Taiwan. Eur Respir J 2003; 21:964-70.
3. Yan DC, Ou LS, Tsai TL, Wu WF, Huang JL. Prevalence and severity of symptoms of asthma, rhinitis, and eczema in 13- to 14-year-old children in Taipei, Taiwan. Ann Allergy Asthma Immunol 2005; 95:579-85.
4. Liao PF, Sun HL, Lu KH, Lue KH. Prevalence of Childhood Allergic Diseases in Central Taiwan over the Past 15 Years. Pediatr Neonatol 2009; 50:18-25.
5. Simons F, Estelle R. Advances in H1-Anti-histamines. N Engl J Med 2004; 351:2203-17.
6. Vuurman EFPM, van Veggel LMA, Uiterwijk MMC, Leutner D, O'Hanlon JF. Seasonal allergic rhinitis and anti-histamine effects on children's learning. Ann Allergy 1993; 71:121-6. (Pubitemid 23245942)
7. Kay GG, Harris AG. Loratadine: a non-sedating anti-histamine. Review of its effects on cognition, psychomotor performance, mood and sedation. Clin Exp Allergy 1999; 29:147-50. (Pubitemid 29333349)
8. Salmun L, Herron J, Banfield C, Padhi D, Lorber R, Affrime MB. The pharmacokinetics, electrocardiographic effects, and tolerability of loratadine syrup in children aged 2 to 5 years. Clin Ther 2000; 22:613-21. (Pubitemid 30434313)
9. Crawford WW, Klaustermeyer WB, Lee PH, Placik IM. Comparative efficacy of terfenadine, loratadine, and astemizole in perennial allergic rhinitis. Otolaryng Head Neck 1998; 118:668-73. (Pubitemid 28222211)
10. Bender BG, McCormick DR, Milgrom H. Children's school performance is not impaired by short-term administration of diphenhydramine or loratadine. J Pediatr 2001; 138:656-60. (Pubitemid 32417664)
11. Skassa-Brociek W, Bousquet J, Montes F, Verdier M, Schwab D, Lherminier M, Michel FB. Double-blind placebo-controlled study of loratadine, mequitazine, and placebo in the symptomatic treatment of seasonal allergic rhinitis. J Allergy Clin Immun 1988; 81:725-30.
12. Homnick DN, Marks JH, Hare KL, Bonnema SK. Long-term trial of Cyproheptadine as an appetite stimulant in cystic fibrosis. Pedatr Pulmonol 2005; 40:251-6. (Pubitemid 41254498)
13. Couluris M, Mayer JLR, Freyer DR, Sandler E, Xu P, Krischer JP. The effect of cyproheptadine hydrochloride (Periactin®) and megesterol acetate (Megace®) on weight in children with cancer/treatment-related cachecia. J Pediatr Hematol Oncol 2008; 30:791-7.
14. Spector SL, Nicklas RA, Chapman JA, et al; and the Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma, and Immunology; American College of Allergy, Asthma, and Immunology; Joint council of Allergy, Asthma, and Immunology. Symptom severity assessment of allergic rhinitis: part 1. Ann Allergy Asthma Immunol 2003; 91:105-14.
15. Bousquet PJ, Combescure C, Neukirch F, Klossek JM, Méchin H, Daures JP, Bousquet J. Visual analog scales can assess the severity of rhinitis graded according to ARIA guidelines. Allergy 2007; 62:367-72. (Pubitemid 46398791)
16. Simons FE. H1-anti-histamine in children. Clin Allergy Immunol 2002; 17:437-64.
17. Plaut M, Valentine MD. Clinical practice. Allergic rhinitis. N Engl J Med 2005; 353:1934-44.
18. Phan H, Moeller ML, Nahata MC. Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast. Drugs 2009; 69:2541-76.
19. Gillman SA, Blatter M, Condemi JJ, Collins M, Olufade AO, Leidy NK, Chapman D, Kramer B. The health-related quality of life effects of once-daily cetirizine HCl syrup in children with seasonal allergic rhinitis. Clin Pediatr 2002; 41:687-96. (Pubitemid 35351170)
20. Simons FE, Silas P, Portnoy JM, Catuogno J, Chapman D, Olufade AO, Pharmd. Safety of cetirizine in infants 6 to 11 months of age: a randomized, double-blind, placebo-controlled study. J Allergy Clin Immunol 2003; 111:1244-8. (Pubitemid 36683677)
21. Simons FE, Early Prevention of Asthma in Atopic Children (EPAAC) Study Group. Safety of levocetirizine treatment in young atopic children: An 18-month study. Pediatr Allergy Immunol 2007; 18:535-42. (Pubitemid 47206747)
22. Salmun LM, Herron JM, Banfield C, Padhi D, Lorber R, Affrime MB. The pharmacokinetics, electrocardiographic effects, and tolerability of Loratadine Syrup in Children Aged 2 to 5 Years. Clin Ther 2000; 22:613-21. (Pubitemid 30434313)
23. Bloom M, Staudinger H, Herron J. Safety of desloratadine syrup in children. Curr Med Res Opin 2004; 20:1959-65. (Pubitemid 40179635)
24. Rossi GA, Tosca MA, Passalacqua G, Bianchi B, Le Grazie C, Canonica GW. Evidence of desloratadine syrup efficacy and tolerability in children with pollen-induced allergic rhinitis. Allergy 2005; 60:416-17. (Pubitemid 40293370)
25. Yang YH, Lin YT, Lu MY, Tsai MJ, Chiang BL. A Double-Blind, Placebo-Controlled, and Randomized Study of Loratadine (Clarityne) Syrup for the Treatment of Allergic Rhinitis in Children Aged 3 to 12 Years. Asian Pac J Allergy 2001; 19:171-5.
26. Bousquet J, Khaltaev N, Cruz AA, et al. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 Update. Allergy 2008; 63:8-160.