The heat shock response in FAP: The role of the extracellular chaperone clusterin

Amyloid

Volumn 19, Issue SUPPL. 1, 2012, Pages 3-4

  Magalhães, Joana ^a,b   Saraiva, Maria João ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Amyloid; Clusterin; Heat shock; Transthyretin

Indexed keywords

CHAPERONE; CLUSTERIN; PREALBUMIN;

CANCER CELL CULTURE; CLUSTER ANALYSIS; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FAMILIAL AMYLOID POLYNEUROPATHY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

AMYLOID NEUROPATHIES, FAMILIAL; CELL LINE, TUMOR; CLUSTERIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEAT-SHOCK RESPONSE; HUMANS; NEUROBLASTOMA; PREALBUMIN;

EID: 84861451360     PISSN: 13506129     EISSN: 17442818     Source Type: Journal    
DOI: 10.3109/13506129.2012.675370     Document Type: Conference Paper

References (4)

1. Saraiva MJ, Birken S, Costa PP, Goodman DS. Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin). J Clin Invest 1984;74:104-119. (Pubitemid 14086050)
2. Yerbury JJ, Stewart EM, Wyatt AR, Wilson MR. Quality control of protein folding in extracellular space. EMBO Rep 2005;6:1131-1136. (Pubitemid 41741695)
3. Poon S, Easterbrook-Smith SB, Rybchyn MS, Carver JA, Wilson MR. Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state. Biochemistry 2000;39:15953-15960. (Pubitemid 32038257)
4. Magalhäes J, Saraiva MJ. Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy. J Neuropathol Exp Neurol 2011;70:1097-1106.